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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2012-09-11 18:37:02 UTC
Update Date2022-03-07 02:53:52 UTC
HMDB IDHMDB0033844
Secondary Accession Numbers
  • HMDB0240576
  • HMDB33844
Metabolite Identification
Common Namebeta-Cryptoxanthin
Descriptionbeta-Cryptoxanthin has been isolated from abalone, fish eggs, and many higher plants. beta-Cryptoxanthin is a major source of vitamin A, often second only to beta-carotene, and is present in fruits such as oranges, tangerines, and papayas (PMID: 8554331 ). Frequent intake of tropical fruits that are rich in beta-cryptoxanthin is associated with higher plasma beta-cryptoxanthin concentrations in Costa Rican adolescents. Papaya intake was the best food predictor of plasma beta-cryptoxanthin concentrations. Subjects that frequently consumed (i.e. greater or equal to 3 times/day) tropical fruits with at least 50 micro g/100 g beta-cryptoxanthin (e.g. papaya, tangerine, orange, watermelon) had twofold the plasma beta-cryptoxanthin concentrations of those with intakes of less than 4 times/week (PMID: 12368412 ). A modest increase in beta-cryptoxanthin intake, equivalent to one glass of freshly squeezed orange juice per day, is associated with a reduced risk of developing inflammatory disorders such as rheumatoid arthritis (PMID: 16087992 ). Higher prediagnostic serum levels of total carotenoids and beta-cryptoxanthin were associated with lower smoking-related lung cancer risk in middle-aged and older men in Shanghai, China (PMID: 11440962 ). Consistent with inhibition of the lung cancer cell growth, beta-cryptoxanthin induced the mRNA levels of retinoic acid receptor beta (RAR-beta) in BEAS-2B cells, although this effect was less pronounced in A549 cells. Furthermore, beta-cryptoxanthin transactivated the RAR-mediated transcription activity of the retinoic acid response element. These findings suggest a mechanism of anti-proliferative action of beta-cryptoxanthin and indicate that beta-cryptoxanthin may be a promising chemopreventive agent against lung cancer (PMID: 16841329 ). Cryptoxanthin is a natural carotenoid pigment. It has been isolated from a variety of sources including the petals and flowers of plants in the genus Physalis, orange rind, papaya, egg yolk, butter, apples, and bovine blood serum. In a pure form, cryptoxanthin is a red crystalline solid with a metallic lustre. It is freely soluble in chloroform, benzene, pyridine, and carbon disulfide. In the human body, cryptoxanthin is converted into vitamin A (retinol) and is therefore considered a provitamin A. As with other carotenoids, cryptoxanthin is an antioxidant and may help prevent free radical damage to cells and DNA, as well as stimulate the repair of oxidative damage to DNA. Structurally, cryptoxanthin is closely related to beta-carotene, with only the addition of a hydroxyl group. It is a member of the class of carotenoids known as xanthophylls.
Structure
Data?1580939542
Synonyms
ValueSource
CryptoxanthinChEBI
b-CryptoxanthinGenerator
Β-cryptoxanthinGenerator
Beta CryptoxanthinHMDB
CryptoxanthinsHMDB
beta-Caroten-3-olHMDB
Beta Caroten 3 olHMDB
(3R)-CryptoxanthinHMDB
(3R)-beta,beta-Caroten-3-olHMDB
(3R)-beta-CryptoxanthinHMDB
(3R)-Β,β-caroten-3-olHMDB
(3R)-Β-cryptoxanthinHMDB
(R)-all-trans-beta-Caroten-3-olHMDB
(R)-all-trans-Β-caroten-3-olHMDB
3-Hydroxy-beta-caroteneHMDB
3-Hydroxy-β-caroteneHMDB
CaricaxanthinHMDB
CryptoxanthineHMDB
CryptoxantholHMDB
KryptoxanthinHMDB
Neo-beta-cryptoxanthinHMDB
Neo-β-cryptoxanthinHMDB
all-trans-CryptoxanthinHMDB
all-trans-CryptoxantholHMDB
all-trans-NeocryptoxanthinHMDB
all-trans-NeocryptoxantholHMDB
all-trans-beta-CryptoxanthinHMDB
all-trans-Β-cryptoxanthinHMDB
trans-CryptoxanthinHMDB
trans-beta-CrytoxanthinHMDB
trans-Β-crytoxanthinHMDB
Β-caroten-3-olHMDB
beta-CryptoxanthinHMDB
Chemical FormulaC40H56O
Average Molecular Weight552.887
Monoisotopic Molecular Weight552.433116423
IUPAC Name(1R)-3,5,5-trimethyl-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-3-en-1-ol
Traditional Namecryptoxanthin
CAS Registry Number472-70-8
SMILES
C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C
InChI Identifier
InChI=1S/C40H56O/c1-30(18-13-20-32(3)23-25-37-34(5)22-15-27-39(37,7)8)16-11-12-17-31(2)19-14-21-33(4)24-26-38-35(6)28-36(41)29-40(38,9)10/h11-14,16-21,23-26,36,41H,15,22,27-29H2,1-10H3/b12-11+,18-13+,19-14+,25-23+,26-24+,30-16+,31-17+,32-20+,33-21+/t36-/m1/s1
InChI KeyDMASLKHVQRHNES-FKKUPVFPSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassTetraterpenoids
Direct ParentXanthophylls
Alternative Parents
Substituents
  • Xanthophyll
  • Secondary alcohol
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Alcohol
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
DispositionNot Available
ProcessNot Available
RoleNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting Point172 - 173 °CNot Available
Boiling Point682.90 °C. @ 760.00 mm Hg (est)The Good Scents Company Information System
Water Solubility1.9e-11 mg/L @ 25 °C (est)The Good Scents Company Information System
LogP13.670 (est)The Good Scents Company Information System
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.0005 g/LALOGPS
logP9.08ALOGPS
logP9.74ChemAxon
logS-6ALOGPS
pKa (Strongest Acidic)18.91ChemAxon
pKa (Strongest Basic)-1.1ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area20.23 ŲChemAxon
Rotatable Bond Count10ChemAxon
Refractivity193.28 m³·mol⁻¹ChemAxon
Polarizability72.71 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DeepCCS[M+H]+262.96130932474
DeepCCS[M-H]-260.99730932474
DeepCCS[M-2H]-294.23830932474
DeepCCS[M+Na]+268.70130932474
AllCCS[M+H]+255.632859911
AllCCS[M+H-H2O]+253.832859911
AllCCS[M+NH4]+257.232859911
AllCCS[M+Na]+257.732859911
AllCCS[M-H]-228.032859911
AllCCS[M+Na-2H]-231.432859911
AllCCS[M+HCOO]-235.332859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
beta-CryptoxanthinC\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C5621.7Standard polar33892256
beta-CryptoxanthinC\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C4703.0Standard non polar33892256
beta-CryptoxanthinC\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C4303.6Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
beta-Cryptoxanthin,1TMS,isomer #1CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O[Si](C)(C)C)CC2(C)C)C(C)(C)CCC14639.0Semi standard non polar33892256
beta-Cryptoxanthin,1TBDMS,isomer #1CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O[Si](C)(C)C(C)(C)C)CC2(C)C)C(C)(C)CCC14822.3Semi standard non polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - beta-Cryptoxanthin GC-MS (1 TMS) - 70eV, PositiveNot Available2020-06-30Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - beta-Cryptoxanthin GC-MS ("beta-Cryptoxanthin,1TMS,#1" TMS) - 70eV, PositiveNot Available2021-10-14Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - beta-Cryptoxanthin GC-MS (TBDMS_1_1) - 70eV, PositiveNot Available2021-10-15Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QIT 20V, positive-QTOFsplash10-03e2-0000940000-3f294d1b8006a14a01ff2020-07-21HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QIT 1V, positive-QTOFsplash10-0gw0-0000590000-7d729e39216a9256dd6e2020-07-21HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 4V, negative-QTOFsplash10-001i-0100390000-6e3ca267c63ed4a7b9672020-07-21HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 7V, positive-QTOFsplash10-0udi-0410290000-a5c664cfd06c2fdd33242020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 10V, positive-QTOFsplash10-0udi-0510490000-039320bed3c92cf5f0882020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 15V, positive-QTOFsplash10-0ik9-1940330000-b3ae219429ec53cbcd4d2020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 17V, positive-QTOFsplash10-0ik9-1920320000-485587903906f2b18dcb2020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 20V, positive-QTOFsplash10-0901-1930100000-4fd08614a2f7381f53d52020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 23V, positive-QTOFsplash10-0cka-1930000000-7f32a39aee17b0a4d9b72020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 25V, positive-QTOFsplash10-07i2-1920000000-83c4e90e75123b21d4e92020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 27V, positive-QTOFsplash10-0aos-1920000000-689e947f9f91e455db442020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 33V, positive-QTOFsplash10-0avj-2910000000-1f4da5545dbcc6e234432020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QTOF 35V, positive-QTOFsplash10-0apj-2910000000-2880fa73a258081c15142020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 10V, positive-QTOFsplash10-0udi-0000090000-0a3807d0b0e0fcf40e232020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 12V, positive-QTOFsplash10-0udi-0000190000-c531fb31efc607bca5392020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 14V, positive-QTOFsplash10-0udi-0000290000-9dcfda517e5c18de5c132020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 16V, positive-QTOFsplash10-0w29-0100590000-8b0595fe54a9ba02ae842020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 18V, positive-QTOFsplash10-0w29-0531890000-cf871a68617fa49216362020-07-22HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - beta-Cryptoxanthin QqQ 20V, positive-QTOFsplash10-0ik9-0961640000-22863b9e3dbec1d448002020-07-22HMDB team, MONAView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 10V, Positive-QTOFsplash10-0f79-0423290000-bf7a8e40a11eff7bfe3c2017-06-28Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 20V, Positive-QTOFsplash10-0002-0649100000-9c3f50cab7f2d02e22fd2017-06-28Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 40V, Positive-QTOFsplash10-002k-0569000000-8a2e2a50f957c26b3ab12017-06-28Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 10V, Negative-QTOFsplash10-0udi-0000090000-d34ae69e503c3f3819112017-06-28Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 20V, Negative-QTOFsplash10-0udi-0000090000-2fe3377fd40bc851dfc42017-06-28Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - beta-Cryptoxanthin 40V, Negative-QTOFsplash10-000i-0546190000-d1d53215d44121d136842017-06-28Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Extracellular
  • Membrane
Biospecimen Locations
  • Blood
  • Breast Milk
  • Feces
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.16 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.18 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.094 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.181 +/- 0.00500 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.150 +/- 0.0800 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.180 +/- 0.120 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.136 +/- 0.150 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.160 +/- 0.110 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.270 +/- 0.170 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.107 +/- 0.130 uMAdult (>18 years old)Male
Normal
details
BloodDetected and Quantified0.180 +/- 0.100 uMAdult (>18 years old)Male
Normal
details
BloodDetected and Quantified0.200 +/- 0.120 uMAdult (>18 years old)Male
Normal
details
BloodDetected and Quantified0.130 +/- 0.180 uMAdult (>18 years old)Not Specified
Normal
details
BloodDetected and Quantified0.327 +/- 0.175 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.620 +/- 0.330 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.700 +/- 0.310 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.09 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.09 uMAdult (>18 years old)Male
Normal
details
BloodDetected and Quantified170 +/- 50 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.313 +/- 0.172 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.147 +/- 0.102 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.14 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.16 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.091 uMAdult (>18 years old)Both
Normal
details
BloodDetected and Quantified0.196 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.245 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.289 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.209 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.23 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.283 uMAdult (>18 years old)Female
Normal
details
BloodDetected and Quantified0.14 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.141 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.422 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.0400 +/- 0.0300 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.130 +/- 0.190 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.150 +/- 0.0850 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.170 +/- 0.112 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.250 +/- 0.350 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.324 +/- 0.174 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.169 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.177 uMAdolescent (13-18 years old)FemaleNormal details
BloodDetected and Quantified0.18 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.215 uMChildren (1-13 years old)FemaleNormal details
BloodDetected and Quantified0.27 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.34 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.190 +/- 0.160 uMAdolescent (13-18 years old)FemaleNormal details
BloodDetected and Quantified0.194 +/- 0.121 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.225 +/- 0.167 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.275 +/- 0.295 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.295 +/- 0.279 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.374 +/- 0.190 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.465 +/- 0.351 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified221.751 +/- 113.408 uMAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.152 uMAdolescent (13-18 years old)MaleNormal details
BloodDetected and Quantified0.16 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.17 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.174 uMChildren (1-13 years old)MaleNormal details
BloodDetected and Quantified0.23 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.116 +/- 0.0778 uMAdult (>18 years old)MaleNormal details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)FemaleNormal details
BloodDetected and Quantified0.125 +/- 0.0742 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.148 +/- 0.101 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.150 +/- 0.160 uMAdolescent (13-18 years old)MaleNormal details
BloodDetected and Quantified0.167 +/- 0.132 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.181 +/- 0.202 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.203 +/- 0.165 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.259 +/- 0.123 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified130 +/- 90 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified240 +/- 160 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified240.381 +/- 118.291 uMAdult (>18 years old)MaleNormal details
BloodDetected and Quantified0.220 +/- 0.210 uMChildren (1 - 13 years old)Not SpecifiedNormal details
Breast MilkDetected but not QuantifiedNot QuantifiedAdult (>18 years old)FemaleNormal details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal
details
Abnormal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.103 +/- 0.110 uMAdult (>18 years old)Not Specified
Obese
details
BloodDetected and Quantified0.135 +/- 0.160 uMAdult (>18 years old)Not Specified
Overweight
details
BloodDetected and Quantified0.420 +/- 0.330 uMAdult (>18 years old)BothType I diabetes details
BloodDetected and Quantified0.100 +/- 0.0500 uMChildren (1 - 13 years old)Not SpecifiedObese details
BloodDetected and Quantified0.180 +/- 0.110 uMChildren (1 - 13 years old)Not SpecifiedOverweight details
Associated Disorders and Diseases
Disease References
Obesity
  1. Vioque J, Weinbrenner T, Asensio L, Castello A, Young IS, Fletcher A: Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects. Br J Nutr. 2007 May;97(5):977-86. [PubMed:17408529 ]
  2. Burrows TL, Warren JM, Colyvas K, Garg ML, Collins CE: Validation of overweight children's fruit and vegetable intake using plasma carotenoids. Obesity (Silver Spring). 2009 Jan;17(1):162-8. doi: 10.1038/oby.2008.495. Epub 2008 Nov 6. [PubMed:18997681 ]
Diabetes mellitus type 1
  1. Granado-Lorencio F, Olmedilla-Alonso B, Blanco-Navarro I, Botella-Romero F, Simal-Anton A: Assessment of carotenoid status and the relation to glycaemic control in type I diabetics: a follow-up study. Eur J Clin Nutr. 2006 Aug;60(8):1000-8. Epub 2006 Feb 1. [PubMed:16452910 ]
Associated OMIM IDs
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB097255
KNApSAcK IDC00000920
Chemspider ID4444647
KEGG Compound IDC08591
BioCyc IDCPD-7409
BiGG IDNot Available
Wikipedia LinkCryptoxanthin
METLIN IDNot Available
PubChem Compound5281235
PDB IDNot Available
ChEBI ID10362
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDrw1701401
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Wingerath T, Stahl W, Sies H: beta-Cryptoxanthin selectively increases in human chylomicrons upon ingestion of tangerine concentrate rich in beta-cryptoxanthin esters. Arch Biochem Biophys. 1995 Dec 20;324(2):385-90. [PubMed:8554331 ]
  2. Irwig MS, El-Sohemy A, Baylin A, Rifai N, Campos H: Frequent intake of tropical fruits that are rich in beta-cryptoxanthin is associated with higher plasma beta-cryptoxanthin concentrations in Costa Rican adolescents. J Nutr. 2002 Oct;132(10):3161-7. [PubMed:12368412 ]
  3. Pattison DJ, Symmons DP, Lunt M, Welch A, Bingham SA, Day NE, Silman AJ: Dietary beta-cryptoxanthin and inflammatory polyarthritis: results from a population-based prospective study. Am J Clin Nutr. 2005 Aug;82(2):451-5. [PubMed:16087992 ]
  4. Yuan JM, Ross RK, Chu XD, Gao YT, Yu MC: Prediagnostic levels of serum beta-cryptoxanthin and retinol predict smoking-related lung cancer risk in Shanghai, China. Cancer Epidemiol Biomarkers Prev. 2001 Jul;10(7):767-73. [PubMed:11440962 ]
  5. Child JA: Haematology reporting. Nurs Times. 1975 Jul 3;71(27):1045-8. [PubMed:1144092 ]
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