Hmdb loader

HMDBP02052 (Bile salt export pump) Metabolite Associations

Displaying metabolite protein links 76 - 100 of 105 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB00024517b,12a-Dihydroxycholanoic acid84413-81-0ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00024887a,12b-dihydroxy-5b-Cholan-24-oic acid84413-82-1ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00024927a-Hydroxy-5b-cholanic acid28083-34-3ThumbC24H40O3376.5726
376.297745146		Not Available
HMDB0002497Glycochenodeoxycholate-3-sulfate67030-54-0ThumbC26H43NO8S529.687
529.270938047		Not Available
HMDB00025043-Sulfodeoxycholic acid67030-48-2ThumbC23H38O7S458.609
458.23382426		Not Available
HMDB0002522Chenodeoxycholic acid sulfate59132-31-9ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0002536Isodeoxycholic acid566-17-6ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00025853beta,12beta-Dihydroxy-5beta-cholanoic acid84848-09-9ThumbC24H40O4392.572
392.292659768		Not Available
HMDB0002586Chenodeoxycholic acid 3-sulfate59132-32-0ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0002642Ursodeoxycholic acid 3-sulfate68780-73-4ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0006898Chenodeoxyglycocholic acidThumbC26H43NO5449.6233
449.314123491		Not Available
HMDB0013866N-Desmethyltamoxifen31750-48-8ThumbC25H27NO357.488
357.209264491
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0013961O-Desmethylverapamil (D-702)ThumbC26H36N2O4440.575
440.26750765
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0014351Reserpine50-55-5ThumbC33H40N2O9608.6787
608.273380888
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
  2. Lecureur V, Sun D, Hargrove P, Schuetz EG, Kim RB, Lan LB, Schuetz JD: Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Mol Pharmacol. 2000 Jan;57(1):24-35. [PubMed:10617675 ]
HMDB0014620Chlorpromazine50-53-3ThumbC17H19ClN2S318.864
318.095747015
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0014644Cimetidine51481-61-9ThumbC10H16N6S252.339
252.115715232
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0014681Vincristine57-22-7ThumbC46H56N4O10824.9576
824.399644032
  1. Lecureur V, Sun D, Hargrove P, Schuetz EG, Kim RB, Lan LB, Schuetz JD: Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Mol Pharmacol. 2000 Jan;57(1):24-35. [PubMed:10617675 ]
HMDB0014699Bosentan147536-97-8ThumbC27H29N5O6S551.614
551.183854375
  1. Fattinger K, Funk C, Pantze M, Weber C, Reichen J, Stieger B, Meier PJ: The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions. Clin Pharmacol Ther. 2001 Apr;69(4):223-31. [PubMed:11309550 ]
HMDB0014710Vinblastine865-21-4ThumbC46H58N4O9810.9741
810.420379474
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
  2. Lecureur V, Sun D, Hargrove P, Schuetz EG, Kim RB, Lan LB, Schuetz JD: Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Mol Pharmacol. 2000 Jan;57(1):24-35. [PubMed:10617675 ]
HMDB0014831Fluorescein2321-07-5ThumbC20H12O5332.3063
332.068473494
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0014832Daunorubicin20830-81-3ThumbC27H29NO10527.5199
527.179146153
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
  2. Lecureur V, Sun D, Hargrove P, Schuetz EG, Kim RB, Lan LB, Schuetz JD: Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Mol Pharmacol. 2000 Jan;57(1):24-35. [PubMed:10617675 ]
HMDB0014983Clofazimine2030-63-9ThumbC27H22Cl2N4473.396
472.122152138
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0015044Quinidine56-54-2ThumbC20H24N2O2324.4168
324.183778022
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0015132Doxorubicin23214-92-8ThumbC27H29NO11543.5193
543.174060775
  1. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
HMDB0015151Glyburide10238-21-8ThumbC23H28ClN3O5S494.004
493.143819418
  1. Stieger B, Fattinger K, Madon J, Kullak-Ublick GA, Meier PJ: Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. Gastroenterology. 2000 Feb;118(2):422-30. [PubMed:10648470 ]
  2. Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. [PubMed:12739759 ]
  3. Byrne JA, Strautnieks SS, Mieli-Vergani G, Higgins CF, Linton KJ, Thompson RJ: The human bile salt export pump: characterization of substrate specificity and identification of inhibitors. Gastroenterology. 2002 Nov;123(5):1649-58. [PubMed:12404239 ]
  4. Kemp DC, Brouwer KL: Viability assessment in sandwich-cultured rat hepatocytes after xenobiotic exposure. Toxicol In Vitro. 2004 Dec;18(6):869-77. [PubMed:15465654 ]
  5. Horikawa M, Kato Y, Tyson CA, Sugiyama Y: Potential cholestatic activity of various therapeutic agents assessed by bile canalicular membrane vesicles isolated from rats and humans. Drug Metab Pharmacokinet. 2003;18(1):16-22. [PubMed:15618715 ]
  6. Noe J, Hagenbuch B, Meier PJ, St-Pierre MV: Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Hepatology. 2001 May;33(5):1223-31. [PubMed:11343252 ]
  7. Funk C, Pantze M, Jehle L, Ponelle C, Scheuermann G, Lazendic M, Gasser R: Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate. Toxicology. 2001 Oct 5;167(1):83-98. [PubMed:11557132 ]
Displaying metabolite protein links 76 - 100 of 105 in total