Hmdb loader
Identification
HMDB Protein ID HMDBP07316
Secondary Accession Numbers
  • 12938
Name Lysophosphatidic acid receptor 6
Synonyms
  1. LPA receptor 6
  2. LPA-6
  3. Oleoyl-L-alpha-lysophosphatidic acid receptor
  4. P2Y purinoceptor 5
  5. P2Y5
  6. Purinergic receptor 5
  7. RB intron encoded G-protein coupled receptor
Gene Name LPAR6
Protein Type Unknown
Biological Properties
General Function Involved in G-protein coupled receptor protein signaling pathway
Specific Function Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture
Pathways
  • Lysophosphatidic Acid LPA6 Signalling
Reactions Not Available
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
nucleotide receptor activity, g-protein coupled
purinergic nucleotide receptor activity, g-protein coupled
receptor activity
transmembrane receptor activity
molecular transducer activity
signal transducer activity
g-protein coupled receptor activity
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Gene Properties
Chromosome Location Chromosome:1
Locus 13q14
SNPs LPAR6
Gene Sequence
>1035 bp
ATGGTAAGCGTTAACAGCTCCCACTGCTTCTATAATGACTCCTTTAAGTACACTTTGTAT
GGGTGCATGTTCAGCATGGTGTTTGTGCTTGGGTTAGTATCCAATTGTGTTGCCATATAC
ATTTTCATCTGCGTCCTCAAAGTCCGAAATGAAACTACAACTTACATGATTAACTTGGCA
ATGTCAGACTTGCTTTTTGTTTTTACTTTACCCTTCAGGATTTTTTACTTCACAACACGG
AATTGGCCATTTGGAGATTTACTTTGTAAGATTTCTGTGATGCTGTTTTATACCAACATG
TACGGAAGCATTCTGTTCTTAACCTGTATTAGTGTAGATCGATTTCTGGCAATTGTCTAC
CCATTTAAGTCAAAGACTCTAAGAACCAAAAGAAATGCAAAGATTGTTTGCACTGGCGTG
TGGTTAACTGTGATCGGAGGAAGTGCACCCGCCGTTTTTGTTCAGTCTACCCACTCTCAG
GGTAACAATGCCTCAGAAGCCTGCTTTGAAAATTTTCCAGAAGCCACATGGAAAACATAT
CTCTCAAGGATTGTAATTTTCATCGAAATAGTGGGATTTTTTATTCCTCTAATTTTAAAT
GTAACTTGTTCTAGTATGGTGCTAAAAACTTTAACCAAACCAGTTACATTAAGTAGAAGC
AAAATAAACAAAACTAAGGTTTTAAAAATGATTTTTGTACATTTGATCATATTCTGTTTC
TGTTTTGTTCCTTACAATATCAATCTTATTTTATATTCTCTTGTGAGAACACAAACATTT
GTTAATTGCTCAGTAGTGGCAGCAGTAAGGACAATGTACCCAATCACTCTCTGTATTGCT
GTTTCCAACTGTTGTTTTGACCCTATAGTTTACTACTTTACATCGGACACAATTCAGAAT
TCAATAAAAATGAAAAACTGGTCTGTCAGGAGAAGTGACTTCAGATTCTCTGAAGTTCAT
GGTGCAGAGAATTTTATTCAGCATAACCTACAGACCTTAAAAAGTAAGATATTTGACAAT
GAATCTGCTGCCTGA
Protein Properties
Number of Residues 344
Molecular Weight 39391.2
Theoretical pI 9.16
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • 20-46
  • 56-79
  • 93-112
  • 134-154
  • 182-209
  • 228-253
  • 273-292
Protein Sequence
>Lysophosphatidic acid receptor 6
MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLA
MSDLLFVFTLPFRIFYFTTRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVY
PFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTY
LSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCF
CFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQN
SIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIFDNESAA
GenBank ID Protein 2232069
UniProtKB/Swiss-Prot ID P43657
UniProtKB/Swiss-Prot Entry Name LPAR6_HUMAN
PDB IDs Not Available
GenBank Gene ID AF000546
GeneCard ID LPAR6
GenAtlas ID LPAR6
HGNC ID HGNC:15520
References
General References
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