Hmdb loader
Identification
HMDB Protein ID HMDBP08181
Secondary Accession Numbers
  • 13892
Name Chloride channel CLIC-like protein 1
Synonyms
  1. Mid-1-related chloride channel protein 1
Gene Name CLCC1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Seems to act as a chloride ion channel
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location
  1. Nucleus
  2. Membrane
  3. Multi-pass membrane protein (Potential)
  4. Golgi apparatus
  5. Endoplasmic reticulum
Gene Properties
Chromosome Location Chromosome:1
Locus 1p13.3
SNPs CLCC1
Gene Sequence
>1657 bp
GATGCTGTGTTCTTTGCTCCTTTGTGAATGCCTGTTGCTGGTAGCTGGTTATGCTCATGA
TGATGACTGGATTGACCCCACAGACATGCTTAACTATGATGCTGCTTCAGGAACAATGAG
AAAATCTCAGGCAAAATATGGTATTTCAGGGGAAAAGGATGTCAGTCCTGACTTGTCATG
TGCTGATGAAATATCAGAATGTTATCACAAACTTGATTCTTTAACTTATAAGATTGATGA
GTGTGAAAAGAAAAAGAGGGAAGACTATGAAAGTCAAAGCAATCCTGTTTTTAGGAGATA
CTTAAATAAGATTTTAATTGAAGCTGGAAAGCTTGGACTTCCTGATGAAAACAAAGGCGA
TATGCATTATGATGCTGAGATTATCCTTAAAAGAGAAACTTTGTTAGAAATACAGAAGTT
TCTCAATGGAGAAGACTGGAAACCAGGTGCCTTGGATGATGCACTAAGTGATATTTTAAT
TAATTTTAAGTTTCATGATTTTGAAACATGGAAGTGGCGATTCGAAGATTCCTTTGGAGT
GGATCCATATAATGTGTTAATGGTACTTCTTTGTCTGCTCTGCATCGTGGTTTTAGTGGC
TACTGAGCTGTGGACATATGTACGTTGGTACACTCAGTTGAGACGTGTTTTAATCATCAG
CTTTCTGTTCAGTTTGGGATGGAATTGGATGTATTTATATAAGCTAGCTTTTGCACAGCA
TCAGGCTGAAGTCGCCAAGATGGAGCCATTAAACAATGTGTGTGCCAAAAAGATGGACTG
GACTGGAAGTATCTGGGAATGGTTTAGAAGTTCATGGACCTATAAGGATGACCCATGCCA
AAAATACTATGAGCTCTTACTAGTCAACCCTATTTGGTTGGTCCCACCAACAAAGGCACT
TGCAGTTACATTCACCACATTTGTAACGGAGCCATTGAAGCATATTGGAAAAGGAACTGG
GGAATTTATTAAAGCACTCATGAAGGAAATTCCAGCGCTGCTTCATCTTCCAGTGCTGAT
AATTATGGCATTAGCCATCCTGAGTTTCTGCTATGGTGCTGGAAAATCAGTTCATGTGCT
GAGACATATAGGCGGTCCTGAGAGCGAACCTCCCCAGGCACTTCGGCCACGGGATAGAAG
ACGGCAGGAGGAAATTGATTATAGACCTGATGGTGGAGCAGGTGATGCCGATTTCCATTA
TAGGGGCCAAATGGGCCCCACTGAGCAAGGCCCTTATGCCAAAACGTATGAGGGTAGAAG
AGAGATTTTGAGAGAGAGAGATGTTGACTTGAGATTTCAGACTGGCAACAAGAGCCCTGA
AGTGCTCCGGGCATTTGATGTACCAGACGCAGAGGCACGAGAGCATCCCACGGTGGTACC
CAGTCATAAATCACCTGTTTTGGATACAAAGCCCAAGGAGACAGGTGGAATCCTGGGGGA
AGGCACACCGAAAGAAAGCAGTACTGAAAGCAGCCAGTCGGCCAAGCCTGTCTCTGGCCA
AGACACATCAGGGAATACAGAAGGTTCACCCGCAGCGGAAAAGGCCCAGCTCAAGTCTGA
AGCCGCAGGCAGCCCAGACCAAGGCAGCACATACAGCCCCGCAAGAGGTGTGGCTGGACC
ACGTGGACAGGATCCGGTCAGCAGCCCCTGTGGCTAG
Protein Properties
Number of Residues 551
Molecular Weight 62022.0
Theoretical pI 5.23
Pfam Domain Function
Signals
  • 1-18
Transmembrane Regions
  • 185-205
  • 217-237
  • 330-350
Protein Sequence
>Chloride channel CLIC-like protein 1
MLCSLLLCECLLLVAGYAHDDDWIDPTDMLNYDAASGTMRKSQAKYGISGEKDVSPDLSC
ADEISECYHKLDSLTYKIDECEKKKREDYESQSNPVFRRYLNKILIEAGKLGLPDENKGD
MHYDAEIILKRETLLEIQKFLNGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGV
DPYNVLMVLLCLLCIVVLVATELWTYVRWYTQLRRVLIISFLFSLGWNWMYLYKLAFAQH
QAEVAKMEPLNNVCAKKMDWTGSIWEWFRSSWTYKDDPCQKYYELLLVNPIWLVPPTKAL
AVTFTTFVTEPLKHIGKGTGEFIKALMKEIPALLHLPVLIIMALAILSFCYGAGKSVHVL
RHIGGPESEPPQALRPRDRRRQEEIDYRPDGGAGDADFHYRGQMGPTEQGPYAKTYEGRR
EILRERDVDLRFQTGNKSPEVLRAFDVPDAEAREHPTVVPSHKSPVLDTKPKETGGILGE
GTPKESSTESSQSAKPVSGQDTSGNTEGSPAAEKAQLKSEAAGSPDQGSTYSPARGVAGP
RGQDPVSSPCG
GenBank ID Protein 27529736
UniProtKB/Swiss-Prot ID Q96S66
UniProtKB/Swiss-Prot Entry Name CLCC1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB018304
GeneCard ID CLCC1
GenAtlas ID CLCC1
HGNC ID HGNC:29675
References
General References
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  3. Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP: A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. [PubMed:18669648 ]
  4. Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007. [PubMed:18691976 ]
  5. Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell. 2006 Nov 3;127(3):635-48. [PubMed:17081983 ]
  6. Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra. J Proteome Res. 2007 Nov;6(11):4150-62. Epub 2007 Oct 9. [PubMed:17924679 ]
  7. Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem. 2009 Jun 1;81(11):4493-501. doi: 10.1021/ac9004309. [PubMed:19413330 ]
  8. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 1998 Oct 30;5(5):277-86. [PubMed:9872452 ]
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