Showing Protein Cyclin-D1-binding protein 1 (HMDBP09058)

• 14800

1. Grap2 and cyclin-D-interacting protein
2. Human homolog of Maid

1. Nucleus
2. Cytoplasm

>1083 bp
ATGGCGAGCGCAACTGCACCTGCAGCCGCAGTCCCCACCCTGGCTTCGCCTTTGGAGCAG
CTCCGGCACTTGGCGGAGGAGCTGCGGTTGCTCCTGCCTCGAGTGCGGGTCGGCGAAGCC
CAGGAGACCACCGAGGAGTTTAATCGAGAGATGTTCTGGAGAAGACTCAATGAGGCAGCT
GTGACTGTGTCAAGGGAAGCCACGACTCTGACCATAGTCTTCTCTCAGCTTCCACTGCCG
TCTCCACAGGAAACCCAGAAGTTCTGTGAACAAGTCCATGCTGCCATCAAGGCATTTATT
GCAGTGTACTATTTGCTTCCAAAGGATCAGGGGATCACCCTGAGAAAGCTGGTACGGGGC
GCCACCCTGGACATCGTGGATGGCATGGCTCAGCTCATGGAAGTACTTTCCGTCACTCCA
ACTCAGAGCCCTGAGAACAATGACCTTATTTCCTACAACAGTGTCTGGGTTGCGTGCCAG
CAGATGCCTCAGATACCAAGAGATAACAAAGCTGCAGCTCTTTTGATGCTGACCAAGAAT
GTGGATTTTGTGAAGGATGCACATGAAGAAATGGAGCAGGCTGTGGAAGAATGTGACCCT
TACTCTGGCCTCTTGAATGATACTGAGGAGAACAACTCTGACAACCACAATCATGAGGAT
GATGTGTTGGGGTTTCCCAGCAATCAGGACTTGTATTGGTCAGAGGACGATCAAGAGCTC
ATAATCCCATGCCTTGCGCTGGTGAGAGCATCCAAAGCCTGCCTGAAGAAAATTCGGATG
TTAGTGGCAGAGAATGGGAAGAAGGATCAGGTGGCACAGCTGGATGACATTGTGGATATT
TCTGATGAAATCAGCCCTAGTGTGGATGATTTGGCTCTGAGCATATATCCACCTATGTGT
CACCTGACCGTGCGAATCAATTCTGCGAAACTTGTATCTGTTTTAAAGAAGGCACTTGAA
ATTACAAAAGCAAGTCATGTGACCCCTCAGCCAGAAGATAGTTGGATCCCTTTACTTATT
AATGCCATTGATCATTGCATGAATAGAATCAAGGAGCTCACTCAGAGTGAACTTGAATTA
TGA

• None

• None

>Cyclin-D1-binding protein 1
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAA
VTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRG
ATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKN
VDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQEL
IIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMC
HLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL

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3. Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9543-8. [PubMed:10931946 ]
4. Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. DNA Res. 2005;12(2):117-26. [PubMed:16303743 ]
5. Yao Y, Doki Y, Jiang W, Imoto M, Venkatraj VS, Warburton D, Santella RM, Lu B, Yan L, Sun XH, Su T, Luo J, Weinstein IB: Cloning and characterization of DIP1, a novel protein that is related to the Id family of proteins. Exp Cell Res. 2000 May 25;257(1):22-32. [PubMed:10854051 ]
6. Terai S, Aoki H, Ashida K, Thorgeirsson SS: Human homologue of maid: A dominant inhibitory helix-loop-helix protein associated with liver-specific gene expression. Hepatology. 2000 Aug;32(2):357-66. [PubMed:10915743 ]
7. Xia C, Bao Z, Tabassam F, Ma W, Qiu M, Hua S, Liu M: GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F-mediated transcriptional activity. J Biol Chem. 2000 Jul 7;275(27):20942-8. [PubMed:10801854 ]
8. Chang MS, Chang CL, Huang CJ, Yang YC: p29, a novel GCIP-interacting protein, localizes in the nucleus. Biochem Biophys Res Commun. 2000 Dec 20;279(2):732-7. [PubMed:11118353 ]
9. Takami T, Terai S, Yokoyama Y, Tanimoto H, Tajima K, Uchida K, Yamasaki T, Sakaida I, Nishina H, Thorgeirsson SS, Okita K: Human homologue of maid is a useful marker protein in hepatocarcinogenesis. Gastroenterology. 2005 May;128(5):1369-80. [PubMed:15887118 ]
10. Ma W, Stafford LJ, Li D, Luo J, Li X, Ning G, Liu M: GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis. J Cell Biochem. 2007 Apr 15;100(6):1376-86. [PubMed:17131381 ]
11. Chang TW, Chen CC, Chen KY, Su JH, Chang JH, Chang MC: Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells. Oncogene. 2008 Jan 10;27(3):332-8. Epub 2007 Jul 9. [PubMed:17621266 ]