Identification |
HMDB Protein ID
| HMDBP12078 |
Secondary Accession Numbers
| None |
Name
| tRNA (cytidine(34)-2'-O)-methyltransferase |
Synonyms
|
- tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL
|
Gene Name
| TRML |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Cellular Component |
cytoplasm |
Molecular Function |
S-adenosylmethionine-dependent methyltransferase activity |
RNA binding |
tRNA methyltransferase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 162 |
Molecular Weight
| 18250.675 |
Theoretical pI
| 6.794 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| C7BSD3 |
UniProtKB/Swiss-Prot Entry Name
| TRML_PHOAA |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Wilkinson P, Waterfield NR, Crossman L, Corton C, Sanchez-Contreras M, Vlisidou I, Barron A, Bignell A, Clark L, Ormond D, Mayho M, Bason N, Smith F, Simmonds M, Churcher C, Harris D, Thompson NR, Quail M, Parkhill J, Ffrench-Constant RH: Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. BMC Genomics. 2009 Jul 7;10:302. doi: 10.1186/1471-2164-10-302. [PubMed:19583835 ]
|