Hmdb loader
Identification
HMDB Protein ID HMDBP12078
Secondary Accession Numbers None
Name tRNA (cytidine(34)-2'-O)-methyltransferase
Synonyms
  1. tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL
Gene Name TRML
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
Pathways Not Available
Reactions Not Available
GO Classification
Cellular Component
cytoplasm
Molecular Function
S-adenosylmethionine-dependent methyltransferase activity
RNA binding
tRNA methyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 162
Molecular Weight 18250.675
Theoretical pI 6.794
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID C7BSD3
UniProtKB/Swiss-Prot Entry Name TRML_PHOAA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Wilkinson P, Waterfield NR, Crossman L, Corton C, Sanchez-Contreras M, Vlisidou I, Barron A, Bignell A, Clark L, Ormond D, Mayho M, Bason N, Smith F, Simmonds M, Churcher C, Harris D, Thompson NR, Quail M, Parkhill J, Ffrench-Constant RH: Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. BMC Genomics. 2009 Jul 7;10:302. doi: 10.1186/1471-2164-10-302. [PubMed:19583835 ]