Identification |
HMDB Protein ID
| HMDBP12150 |
Secondary Accession Numbers
| None |
Name
| Thrombin-like enzyme elegaxobin-2 |
Synonyms
|
- SVTLE
- Elegaxobin II
- Fibrinogen-clotting enzyme
- Snake venom serine protease
- SVSP
|
Gene Name
| Not Available |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Thrombin-like snake venom serine protease that clots rabbit fibrinogen. Only the beta chain of fibrinogen (FGB) is cleaved, releasing fibrinopeptide B. Human and bovine fibrinogen are unaffected. Also cleaves Met-Lys and Arg-Ser bonds in heat-denatured bovine plasma kininogen to release Lys-bradykinin. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
regulation of blood pressure |
envenomation resulting in fibrinogenolysis in other organism |
envenomation resulting in negative regulation of blood coagulation in other organism |
Cellular Component |
extracellular region |
Molecular Function |
toxin activity |
serine-type endopeptidase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 25590.79 |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P84787 |
UniProtKB/Swiss-Prot Entry Name
| VSP2_PROEL |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Oyama E, Takahashi H: Amino acid sequence of a thrombin like enzyme, elegaxobin II, from the venom of Trimeresurus elegans (Sakishima-Habu). Toxicon. 2004 Dec 1;44(7):711-21. doi: 10.1016/j.toxicon.2004.07.007. [PubMed:15500847 ]
- Oyama E, Takahashi H: Purification and characterization of a thrombin like enzyme, elegaxobin II, with lys-bradykinin releasing activity from the venom of Trimeresurus elegans (Sakishima-Habu). Toxicon. 2003 Apr;41(5):559-68. doi: 10.1016/s0041-0101(02)00363-x. [PubMed:12676434 ]
|