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Showing Protein 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (HMDBP12245)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP12245
Secondary Accession Numbers None
Name 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
Synonyms
  1. 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase
Gene Name ISPG
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
Pathways
  • Biosynthesis of secondary metabolites
  • isopentenyl diphosphate biosynthesis via DXP pathway
  • Terpenoid backbone biosynthesis
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
terpenoid biosynthetic process
Molecular Function
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity
4 iron, 4 sulfur cluster binding
iron ion binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 613
Molecular Weight 67896.0
Theoretical pI 5.252
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8A4T0
UniProtKB/Swiss-Prot Entry Name ISPG_BACTN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Xu J, Bjursell MK, Himrod J, Deng S, Carmichael LK, Chiang HC, Hooper LV, Gordon JI: A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science. 2003 Mar 28;299(5615):2074-6. doi: 10.1126/science.1080029. [PubMed:12663928 ]