| Identification |
|---|
| HMDB Protein ID
| HMDBP12933 |
| Secondary Accession Numbers
| None |
| Name
| Pentafunctional AROM polypeptide |
| Synonyms
|
Not Available
|
| Gene Name
| (REFSEQ) 3-DEHYDROQUINATE SYNTHASE |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cellular amino acid biosynthetic process |
| aromatic amino acid family biosynthetic process |
| chorismate biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| metal ion binding |
| ATP binding |
| 3-dehydroquinate dehydratase activity |
| 3-dehydroquinate synthase activity |
| 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| shikimate 3-dehydrogenase (NADP+) activity |
| shikimate kinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 1538 |
| Molecular Weight
| 167078.125 |
| Theoretical pI
| 7.029 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A6R8Q8 |
| UniProtKB/Swiss-Prot Entry Name
| ARO1_AJECN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Sharpton TJ, Stajich JE, Rounsley SD, Gardner MJ, Wortman JR, Jordar VS, Maiti R, Kodira CD, Neafsey DE, Zeng Q, Hung CY, McMahan C, Muszewska A, Grynberg M, Mandel MA, Kellner EM, Barker BM, Galgiani JN, Orbach MJ, Kirkland TN, Cole GT, Henn MR, Birren BW, Taylor JW: Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives. Genome Res. 2009 Oct;19(10):1722-31. doi: 10.1101/gr.087551.108. Epub 2009 Aug 28. [PubMed:19717792 ]
|
