Hmdb loader
Identification
HMDB Protein ID HMDBP12939
Secondary Accession Numbers None
Name Pentafunctional AROM polypeptide
Synonyms Not Available
Gene Name (REFSEQ) HYPOTHETICAL PROTEIN
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
Pathways
  • Biosynthesis of amino acids
  • Biosynthesis of secondary metabolites
  • chorismate biosynthesis
  • Phenylalanine, tyrosine and tryptophan biosynthesis
Reactions Not Available
GO Classification
Biological Process
cellular amino acid biosynthetic process
aromatic amino acid family biosynthetic process
chorismate biosynthetic process
Cellular Component
cytoplasm
Molecular Function
metal ion binding
ATP binding
3-dehydroquinate dehydratase activity
3-dehydroquinate synthase activity
3-phosphoshikimate 1-carboxyvinyltransferase activity
shikimate 3-dehydrogenase (NADP+) activity
shikimate kinase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 1611
Molecular Weight 173471.99
Theoretical pI 6.465
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P0CM23
UniProtKB/Swiss-Prot Entry Name ARO1_CRYNB
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, Donlin MJ, D'Souza CA, Fox DS, Grinberg V, Fu J, Fukushima M, Haas BJ, Huang JC, Janbon G, Jones SJ, Koo HL, Krzywinski MI, Kwon-Chung JK, Lengeler KB, Maiti R, Marra MA, Marra RE, Mathewson CA, Mitchell TG, Pertea M, Riggs FR, Salzberg SL, Schein JE, Shvartsbeyn A, Shin H, Shumway M, Specht CA, Suh BB, Tenney A, Utterback TR, Wickes BL, Wortman JR, Wye NH, Kronstad JW, Lodge JK, Heitman J, Davis RW, Fraser CM, Hyman RW: The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science. 2005 Feb 25;307(5713):1321-4. doi: 10.1126/science.1103773. Epub 2005 Jan 13. [PubMed:15653466 ]