| Identification |
|---|
| HMDB Protein ID
| HMDBP12973 |
| Secondary Accession Numbers
| None |
| Name
| Pentafunctional AROM polypeptide |
| Synonyms
|
Not Available
|
| Gene Name
| (REFSEQ) PENTAFUNCTIONAL AROM POLYPEPTIDE |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cellular amino acid biosynthetic process |
| aromatic amino acid family biosynthetic process |
| chorismate biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| metal ion binding |
| ATP binding |
| 3-dehydroquinate dehydratase activity |
| 3-dehydroquinate synthase activity |
| 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| shikimate 3-dehydrogenase (NADP+) activity |
| shikimate kinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 1598 |
| Molecular Weight
| 173936.585 |
| Theoretical pI
| 7.162 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| C1FYJ9 |
| UniProtKB/Swiss-Prot Entry Name
| ARO1_PARBD |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Desjardins CA, Champion MD, Holder JW, Muszewska A, Goldberg J, Bailao AM, Brigido MM, Ferreira ME, Garcia AM, Grynberg M, Gujja S, Heiman DI, Henn MR, Kodira CD, Leon-Narvaez H, Longo LV, Ma LJ, Malavazi I, Matsuo AL, Morais FV, Pereira M, Rodriguez-Brito S, Sakthikumar S, Salem-Izacc SM, Sykes SM, Teixeira MM, Vallejo MC, Walter ME, Yandava C, Young S, Zeng Q, Zucker J, Felipe MS, Goldman GH, Haas BJ, McEwen JG, Nino-Vega G, Puccia R, San-Blas G, Soares CM, Birren BW, Cuomo CA: Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis. PLoS Genet. 2011 Oct;7(10):e1002345. doi: 10.1371/journal.pgen.1002345. Epub 2011 Oct 27. [PubMed:22046142 ]
|
