Identification |
HMDB Protein ID
| HMDBP12998 |
Secondary Accession Numbers
| None |
Name
| Quinate/shikimate dehydrogenase |
Synonyms
|
- NAD-dependent shikimate 5-dehydrogenase
|
Gene Name
| YDIB |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD. |
Pathways
|
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
cellular amino acid biosynthetic process |
aromatic amino acid family biosynthetic process |
chorismate biosynthetic process |
Molecular Function |
shikimate 3-dehydrogenase (NADP+) activity |
quinate 3-dehydrogenase (NAD+) activity |
quinate 3-dehydrogenase (NADP+) activity |
shikimate 3-dehydrogenase (NAD+) activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 288 |
Molecular Weight
| 31241.595 |
Theoretical pI
| 5.161 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| A1ABM9 |
UniProtKB/Swiss-Prot Entry Name
| YDIB_ECOK1 |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK: The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. J Bacteriol. 2007 Apr;189(8):3228-36. doi: 10.1128/JB.01726-06. Epub 2007 Feb 9. [PubMed:17293413 ]
|