| Identification |
|---|
| HMDB Protein ID
| HMDBP13087 |
| Secondary Accession Numbers
| None |
| Name
| Pyridoxal 5'-phosphate synthase subunit PdxS |
| Synonyms
|
- PLP synthase subunit PdxS
- Pdx1
|
| Gene Name
| PDXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. |
| Pathways
|
- Biosynthesis of cofactors
- pyridoxal 5'-phosphate biosynthesis
- Vitamin B6 metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| pyridoxal phosphate biosynthetic process |
| Molecular Function |
| pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 287 |
| Molecular Weight
| 30818.28 |
| Theoretical pI
| 5.308 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A0Q5I1 |
| UniProtKB/Swiss-Prot Entry Name
| PDXS_FRATN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, Haugen E, Bovee D, Zhou Y, Chang J, Levy R, Lim R, Gillett W, Guenthener D, Kang A, Shaffer SA, Taylor G, Chen J, Gallis B, D'Argenio DA, Forsman M, Olson MV, Goodlett DR, Kaul R, Miller SI, Brittnacher MJ: Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol. 2007;8(6):R102. doi: 10.1186/gb-2007-8-6-r102. [PubMed:17550600 ]
|
