| Identification |
|---|
| HMDB Protein ID
| HMDBP13344 |
| Secondary Accession Numbers
| None |
| Name
| Pyrimidine/purine nucleoside phosphorylase |
| Synonyms
|
- Adenosine phosphorylase
- Cytidine phosphorylase
- Guanosine phosphorylase
- Inosine phosphorylase
- Thymidine phosphorylase
- Uridine phosphorylase
- Xanthosine phosphorylase
|
| Gene Name
| PPNP |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. |
| Pathways
|
- Biosynthesis of secondary metabolites
- Purine metabolism
- Pyrimidine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Molecular Function |
| pyrimidine-nucleoside phosphorylase activity |
| thymidine phosphorylase activity |
| uridine phosphorylase activity |
| purine-nucleoside phosphorylase activity |
| guanosine phosphorylase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 94 |
| Molecular Weight
| 10188.465 |
| Theoretical pI
| 4.989 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PFU0 |
| UniProtKB/Swiss-Prot Entry Name
| PPNP_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
