| Identification |
|---|
| HMDB Protein ID
| HMDBP13347 |
| Secondary Accession Numbers
| None |
| Name
| Solute carrier organic anion transporter family member 3A1 |
| Synonyms
|
- Organic anion-transporting polypeptide D
- Prostaglandin transporter subtype 2
- Sodium-independent organic anion transporter D
- Solute carrier family 21 member 11
- OATP-D
|
| Gene Name
| SLCO3A1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Mediates the Na(+)-independent transport of organic anions. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| sodium-independent organic anion transport |
| positive regulation of protein phosphorylation |
| positive regulation of NF-kappaB transcription factor activity |
| prostaglandin transport |
| Cellular Component |
| plasma membrane |
| integral to plasma membrane |
| Molecular Function |
| sodium-independent organic anion transmembrane transporter activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 710 |
| Molecular Weight
| 76824.505 |
| Theoretical pI
| 7.055 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 41-60;80-100;107-131;175-203;223-243;262-286;345-366;387-410;415-438;540-562;572-597;631-648;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q99N02 |
| UniProtKB/Swiss-Prot Entry Name
| SO3A1_RAT |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Huber RD, Gao B, Sidler Pfandler MA, Zhang-Fu W, Leuthold S, Hagenbuch B, Folkers G, Meier PJ, Stieger B: Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain. Am J Physiol Cell Physiol. 2007 Feb;292(2):C795-806. Epub 2006 Sep 13. [PubMed:16971491 ]
|
