Hmdb loader
Identification
HMDB Protein ID HMDBP13373
Secondary Accession Numbers None
Name Apyrase
Synonyms
  1. ATP-diphosphatase
  2. ATP-diphosphohydrolase
  3. Adenosine diphosphatase
  4. ADPase
Gene Name Not Available
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Facilitates hematophagy by inhibiting ADP-dependent platelet aggregation in the host. May reduce probing time by facilitating the speed of locating blood. Platelet aggregation was inhibited by 6% when 0.4 uM recombinant apyrase was added and by 9.5% when the concentration of recombinant apyrase was 0.8 uM.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
nucleotide catabolic process
Cellular Component
extracellular region
Molecular Function
metal ion binding
8-oxo-dGTP phosphohydrolase activity
dATP phosphohydrolase activity
dCTP phosphohydrolase activity
dGTP phosphohydrolase activity
dTTP phosphohydrolase activity
dUTP phosphohydrolase activity
GTP phosphohydrolase activity
ATP binding
hydrolase activity, acting on ester bonds
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 62750.425
Theoretical pI Not Available
Pfam Domain Function
Signals
  • 1-25;
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID E0D877
UniProtKB/Swiss-Prot Entry Name APY_AEDAL
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Dong F, Fu Y, Li X, Jiang J, Sun J, Cheng X: Cloning, expression, and characterization of salivary apyrase from Aedes albopictus. Parasitol Res. 2012 Feb;110(2):931-7. doi: 10.1007/s00436-011-2579-x. Epub 2011 Aug 14. [PubMed:21842387 ]
  2. Arca B, Lombardo F, Francischetti IM, Pham VM, Mestres-Simon M, Andersen JF, Ribeiro JM: An insight into the sialome of the adult female mosquito Aedes albopictus. Insect Biochem Mol Biol. 2007 Feb;37(2):107-27. doi: 10.1016/j.ibmb.2006.10.007. Epub 2006 Nov 7. [PubMed:17244540 ]