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Showing Protein Snake venom metalloproteinase bothrojaractivase (HMDBP13523)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP13523
Secondary Accession Numbers None
Name Snake venom metalloproteinase bothrojaractivase
Synonyms
  1. SVMP
Gene Name Not Available
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Prothrombin (F2) activator that is cofactor-independent. Also has fibrinolytic and fibrinogenolytic activity. It degrades the Aalpha-chain and more slowly the Bbeta-chain of fibrin and fibrinogen, while the gamma-chain is only partially and slowly affected. A dose-dependent procoagulant activity is shown in human plasma.
Pathways Not Available
Reactions Not Available
GO Classification
Cellular Component
extracellular region
Molecular Function
metal ion binding
peptidase activator activity
toxin activity
metallopeptidase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 7166.235
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P0C7A9
UniProtKB/Swiss-Prot Entry Name VM1BJ_BOTJA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Berger M, Pinto AF, Guimaraes JA: Purification and functional characterization of bothrojaractivase, a prothrombin-activating metalloproteinase isolated from Bothrops jararaca snake venom. Toxicon. 2008 Mar 15;51(4):488-501. doi: 10.1016/j.toxicon.2007.09.005. Epub 2008 Feb 11. [PubMed:18262582 ]