Identification |
HMDB Protein ID
| HMDBP13525 |
Secondary Accession Numbers
| None |
Name
| Snake venom metalloproteinase BjussuMP-2 |
Synonyms
|
- SVMP
- BOJUMET I
- BjussuMP-II
- Nonhemorrhagic metalloprotease MP-II
|
Gene Name
| Not Available |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| This metalloproteinase displays proteolytic activity on fibrin, fibrinogen, collagen, casein and gelatin. It inhibits ADP- and collagen-induced platelet aggregation and displays a very low edema inducing activity. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Cellular Component |
extracellular region |
Molecular Function |
metal ion binding |
toxin activity |
metalloendopeptidase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 41956.76 |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q7T1T4 |
UniProtKB/Swiss-Prot Entry Name
| VM1B2_BOTJR |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Kashima S, Roberto PG, Soares AM, Astolfi-Filho S, Pereira JO, Giuliati S, Faria M Jr, Xavier MA, Fontes MR, Giglio JR, Franca SC: Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2. Biochimie. 2004 Mar;86(3):211-9. doi: 10.1016/j.biochi.2004.02.002. [PubMed:15134836 ]
- Marcussi S, Bernardes CP, Santos-Filho NA, Mazzi MV, Oliveira CZ, Izidoro LF, Fuly AL, Magro AJ, Braz AS, Fontes MR, Giglio JR, Soares AM: Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity. Peptides. 2007 Dec;28(12):2328-39. doi: 10.1016/j.peptides.2007.10.010. Epub 2007 Oct 22. [PubMed:18006118 ]
|