Hmdb loader
Identification
HMDB Protein ID HMDBP13526
Secondary Accession Numbers None
Name Thrombin-like enzyme barnettobin
Synonyms
  1. Bb-TLE
  2. SVTLE
  3. Snake venom serine protease
  4. SVSP
Gene Name Not Available
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Thrombin-like snake venom serine protease that releases only fibrinopeptide A from human Aalpha chain of fibrinogen (specific coagulant activity was 251.7 NIH thrombin units/mg). Also shows fibrino(geno)lytic activities in vitro and defibrinogenating effects in vivo.
Pathways Not Available
Reactions Not Available
GO Classification
Cellular Component
extracellular region
Molecular Function
toxin activity
serine-type endopeptidase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 27584.37
Theoretical pI Not Available
Pfam Domain Function
Signals
  • 1-10;
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID K4LLQ2
UniProtKB/Swiss-Prot Entry Name VSP_BOTBA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Vivas-Ruiz DE, Sandoval GA, Mendoza J, Inga RR, Gontijo S, Richardson M, Eble JA, Yarleque A, Sanchez EF: Coagulant thrombin-like enzyme (barnettobin) from Bothrops barnetti venom: molecular sequence analysis of its cDNA and biochemical properties. Biochimie. 2013 Jul;95(7):1476-86. doi: 10.1016/j.biochi.2013.03.015. Epub 2013 Apr 9. [PubMed:23578498 ]