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Identification
HMDB Protein ID HMDBP14118
Secondary Accession Numbers None
Name Rho GTPase-activating protein 9
Synonyms
  1. Rho-type GTPase-activating protein 9
Gene Name ARHGAP9
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
signal transduction
neutrophil degranulation
regulation of small GTPase mediated signal transduction
regulation of GTPase activity
Cellular Component
cytosol
cytoplasm
extracellular region
secretory granule lumen
Molecular Function
phosphatidylinositol-3,4,5-trisphosphate binding
GTPase activator activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 750
Molecular Weight 83258.655
Theoretical pI 8.336
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9BRR9
UniProtKB/Swiss-Prot Entry Name RHG09_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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