Hmdb loader
Identification
HMDB Protein ID HMDBP14562
Secondary Accession Numbers None
Name Transforming growth factor beta receptor type 3
Synonyms
  1. TGF-beta receptor type 3
  2. TGFR-3
  3. Betaglycan
  4. Transforming growth factor beta receptor III
  5. TGF-beta receptor type III
Gene Name TGFBR3
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
signal transduction
response to follicle-stimulating hormone stimulus
cell migration
BMP signaling pathway
negative regulation of cellular component movement
epithelial to mesenchymal transition
angiogenesis
immune response
vasculogenesis
regulation of transforming growth factor beta receptor signaling pathway
transforming growth factor beta receptor signaling pathway
intracellular signal transduction
Cellular Component
cell surface
collagen-containing extracellular matrix
extracellular space
external side of plasma membrane
integral to membrane
Molecular Function
transforming growth factor beta binding
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type III
coreceptor activity
heparin binding
type II transforming growth factor beta receptor binding
glycosaminoglycan binding
transforming growth factor beta receptor binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 848
Molecular Weight 93004.025
Theoretical pI 6.589
Pfam Domain Function
Signals
  • 1-20;
Transmembrane Regions
  • 785-806;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P35054
UniProtKB/Swiss-Prot Entry Name TGBR3_PIG
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Moren A, Ichijo H, Miyazono K: Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors. Biochem Biophys Res Commun. 1992 Nov 30;189(1):356-62. doi: 10.1016/0006-291x(92)91566-9. [PubMed:1333192 ]