Hmdb loader
Identification
HMDB Protein ID HMDBP14593
Secondary Accession Numbers None
Name Acidic phospholipase A2 Ts-A5
Synonyms
  1. svPLA2
  2. CTs-A5
  3. Phosphatidylcholine 2-acylhydrolase
Gene Name Not Available
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Snake venom phospholipase A2 (PLA2) that shows a moderate inhibition of ADP-induced human platelet aggregation when tested on platelet rich plasma. Exhibits high hydrolytic activities and prefers the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
lipid catabolic process
Cellular Component
extracellular region
Molecular Function
phospholipase A2 activity
metal ion binding
toxin activity
phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 2651.09
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P0DJP7
UniProtKB/Swiss-Prot Entry Name PA2AE_TRIST
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Tsai IH, Wang YM, Chen YH, Tsai TS, Tu MC: Venom phospholipases A2 of bamboo viper (Trimeresurus stejnegeri): molecular characterization, geographic variations and evidence of multiple ancestries. Biochem J. 2004 Jan 1;377(Pt 1):215-23. doi: 10.1042/BJ20030818. [PubMed:12959640 ]