it inhibits mitosis and induces cell death by acting as a topoisomerase ii poison. topoisomerase ii is an enzyme in the nucleus of cells that unwinds dna by making transient double-stranded breaks, relieving the torsion of supercoiled dna.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Etoposide Action Pathway'