it is a non-nucleoside reverse transcriptase inhibitor (nnrti) that binds to the tyrosines at amino acid residues 181 and 188 of hiv-1 reverse transcriptase. nevirapine is metabolized in the liver to 2-, 3-, 8-, and 12-hydroxynevirapine by the induction of cyp enzymes, mainly cyp3a4 and cyp2b6.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Nevirapine Metabolism Pathway'