hmg-coa reductase is the enzyme responsible for the conversion of hmg-coa to mevalonic acid, the rate-limiting step of cholesterol synthesis by this pathway. the active form of statins bears a chemical resemblance to the reduced hmg-coa reaction intermediate that is formed during catalysis.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Rosuvastatin Action Pathway'