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Record Information |
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Version | 4.0 |
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Status | Detected and Quantified |
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Creation Date | 2005-11-16 15:48:42 UTC |
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Update Date | 2019-01-11 19:14:06 UTC |
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HMDB ID | HMDB0000149 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | Ethanolamine |
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Description | Ethanolamine is a viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorometric reagent, and to remove CO2 and H2S from natural gas and other gases. Ethanolamine is found to be associated with maple syrup urine disease and propionic acidemia, which are inborn errors of metabolism. |
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Structure | |
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Synonyms | Value | Source |
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1-amino-2-Hydroxyethane | ChEBI | 2-amino-1-Ethanol | ChEBI | 2-amino-Ethanol | ChEBI | 2-Aminoethan-1-ol | ChEBI | 2-Aminoethyl alcohol | ChEBI | 2-Hydroxyethylamine | ChEBI | Aethanolamin | ChEBI | Aminoethanol | ChEBI | beta-Aminoethanol | ChEBI | beta-Aminoethyl alcohol | ChEBI | beta-Ethanolamine | ChEBI | beta-Hydroxyethylamine | ChEBI | Colamine | ChEBI | ETA | ChEBI | Glycinol | ChEBI | Hea | ChEBI | MEA | ChEBI | MONOETHANOLAMINE | ChEBI | b-Aminoethanol | Generator | β-aminoethanol | Generator | b-Aminoethyl alcohol | Generator | β-aminoethyl alcohol | Generator | b-Ethanolamine | Generator | β-ethanolamine | Generator | b-Hydroxyethylamine | Generator | β-hydroxyethylamine | Generator | 2-Aminoethanol | HMDB | 2-Ethanolamine | HMDB | 2-Hydroxyethanamine | HMDB | Envision conditioner PDD 9020 | HMDB | Ethylolamine | HMDB | H-Glycinol | HMDB | Monoaethanolamin | HMDB | Olamine | HMDB | 2 Aminoethanol | MeSH |
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Chemical Formula | C2H7NO |
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Average Molecular Weight | 61.0831 |
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Monoisotopic Molecular Weight | 61.052763851 |
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IUPAC Name | 2-aminoethan-1-ol |
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Traditional Name | ethanolamine |
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CAS Registry Number | 141-43-5 |
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SMILES | NCCO |
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InChI Identifier | InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2 |
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InChI Key | HZAXFHJVJLSVMW-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom. |
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Kingdom | Organic compounds |
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Super Class | Organic nitrogen compounds |
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Class | Organonitrogen compounds |
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Sub Class | Amines |
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Direct Parent | 1,2-aminoalcohols |
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Alternative Parents | |
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Substituents | - 1,2-aminoalcohol
- Organic oxygen compound
- Organopnictogen compound
- Hydrocarbon derivative
- Primary amine
- Primary alcohol
- Organooxygen compound
- Primary aliphatic amine
- Alcohol
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Ontology |
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Disposition | Route of exposure: Source: Biological location: |
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Process | Naturally occurring process: |
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Role | Industrial application: |
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Physical Properties |
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State | Liquid |
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Experimental Properties | Property | Value | Reference |
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Melting Point | 10.5 °C | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | 1000 mg/mL | Not Available | LogP | -1.31 | HANSCH,C ET AL. (1995) |
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Predicted Properties | |
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Spectra | Spectrum Type | Description | Splash Key | |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-00di-1900000000-b64e859a0bfc46cdfcbf | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-00di-1900000000-384c99d021f0303a9d78 | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized) | splash10-00di-1900000000-d731dd07c2dfa0287f5f | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-00di-8900000000-ec4268b6041043d15437 | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-MS (3 TMS) | splash10-00di-2900000000-02697b8ce238020537aa | View in MoNA |
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GC-MS | GC-MS Spectrum - EI-B (Non-derivatized) | splash10-001i-9000000000-7160c3fea0c0159e447a | View in MoNA |
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GC-MS | GC-MS Spectrum - EI-B (Non-derivatized) | splash10-001i-9000000000-2af16a98e43fadfa86a3 | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-00di-1900000000-b64e859a0bfc46cdfcbf | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-00di-1900000000-384c99d021f0303a9d78 | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-00di-1900000000-d731dd07c2dfa0287f5f | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-00di-8900000000-ec4268b6041043d15437 | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-00di-2900000000-02697b8ce238020537aa | View in MoNA |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0fki-2900000000-37831b0ceb554ca4edd2 | View in MoNA |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-001i-9000000000-e06e8502ffb0d4113432 | View in MoNA |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive | splash10-001i-9100000000-e2cbdef448451ceae424 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated) | splash10-03dl-9000000000-17dee0c07bf5cddb79ce | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated) | splash10-03di-9000000000-04f4c1792f8ab4f4646f | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated) | splash10-03di-9000000000-761836be8f1018081210 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - EI-B (HITACHI RMU-7M) , Positive | splash10-001i-9000000000-7160c3fea0c0159e447a | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - EI-B (HITACHI M-68) , Positive | splash10-001i-9000000000-2af16a98e43fadfa86a3 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive | splash10-03di-9000000000-ae5b80bd3c5c11914ea6 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive | splash10-0006-9000000000-6abb3d0944e188778c65 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive | splash10-0007-9000000000-e477e52f411d933a30b7 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive | splash10-0006-9000000000-d7979261a3716365d5ae | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive | splash10-03di-9000000000-5c0261b2dcc6ae1291a1 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ , positive | splash10-03di-9000000000-ae5b80bd3c5c11914ea6 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ , positive | splash10-0006-9000000000-6abb3d0944e188778c65 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ , positive | splash10-0007-9000000000-e477e52f411d933a30b7 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ , positive | splash10-0006-9000000000-d7979261a3716365d5ae | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ , positive | splash10-03di-9000000000-5c0261b2dcc6ae1291a1 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-03di-9000000000-9e6d219a7fbd8624cd6b | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-01ox-9000000000-fb9020ee9b301ec7766f | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0006-9000000000-a4ae359cfcc0245b4d19 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-03di-9000000000-b6ed81bc049b8d3042f6 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-03dl-9000000000-78c77096ed599182b5bb | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9000000000-f199cbf8312e0b466f1b | View in MoNA |
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MS | Mass Spectrum (Electron Ionization) | splash10-001i-9000000000-b8e7ed9f5ad724511431 | View in MoNA |
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1D NMR | 1H NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 13C NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 1H NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 13C NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 1H NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 1H NMR Spectrum | Not Available | View in JSpectraViewer |
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1D NMR | 13C NMR Spectrum | Not Available | View in JSpectraViewer |
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2D NMR | [1H,1H] 2D NMR Spectrum | Not Available | View in JSpectraViewer |
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2D NMR | [1H,13C] 2D NMR Spectrum | Not Available | View in JSpectraViewer |
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Biological Properties |
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Cellular Locations | |
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Biospecimen Locations | - Blood
- Breast Milk
- Cerebrospinal Fluid (CSF)
- Feces
- Saliva
- Urine
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Tissue Locations | - Brain
- Epidermis
- Most Tissues
- Myelin
- Nerve Cells
- Pancreas
- Stratum Corneum
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Pathways | |
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Normal Concentrations |
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Blood | Detected and Quantified | 52.3 (26.2-91.7) uM | Newborn (0-30 days old) | Both | Normal | | details | Blood | Detected and Quantified | 1.6 (0.0-11.5) uM | Adult (>18 years old) | Both | Normal | | details | Breast Milk | Detected and Quantified | 46.2 +/- 18.1 uM | Adult (>18 years old) | Female | Normal | | details | Cerebrospinal Fluid (CSF) | Detected and Quantified | 14.1 +/- 3.0 uM | Adult (>18 years old) | Both | Normal | | details | Cerebrospinal Fluid (CSF) | Detected and Quantified | 8.43 (2.62-14.24) uM | Adult (>18 years old) | Both | Normal | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Normal | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Normal | | details | Feces | Detected but not Quantified | | Infant (0-1 year old) | Not Available | Normal | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Not Specified | Normal | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Female | Normal | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Normal | | details | Feces | Detected but not Quantified | | Not Specified | Not Specified | Normal | | details | Feces | Detected but not Quantified | | Infant (0-1 year old) | Not Specified | Normal | | details | Feces | Detected but not Quantified | | Infant (0-1 year old) | Not Specified | Normal | | details | Feces | Detected but not Quantified | | Infant (0-1 year old) | Both | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Both | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Male | Normal | | details | Saliva | Detected and Quantified | 135.99 +/- 96.22 uM | Adult (>18 years old) | Both | Normal | | details | Urine | Detected and Quantified | 30.9 umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | Urine | Detected and Quantified | 4.91-24.57 umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | Urine | Detected and Quantified | 42.75 umol/mmol creatinine | Adult (>18 years old) | Male | Normal | | details | Urine | Detected and Quantified | 37.1 (24.8-56.2) umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | Urine | Detected and Quantified | 73.129 +/- 27.908 umol/mmol creatinine | Children (1 - 13 years old) | Not Specified | Normal | | details | Urine | Detected and Quantified | 29.5 +/- 7.8 umol/mmol creatinine | Adult (>18 years old) | Both | Normal | - Geigy Scientific ...
- West Cadwell, N.J...
- Basel, Switzerlan...
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Abnormal Concentrations |
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Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Colorectal Cancer | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Irritable bowel syndrome | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Ulcerative colitis | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Colorectal cancer | | details | Feces | Detected but not Quantified | | Adult (>18 years old) | Both | Colorectal cancer | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Both | Oral cancer | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Female | Breast cancer | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Not Specified | Pancreatic cancer | | details | Saliva | Detected but not Quantified | | Adult (>18 years old) | Not Specified | Periodontal diseases | | details | Urine | Detected and Quantified | 0.0028 - 0.0087 umol/mmol creatinine | Adult (>18 years old) | Both | ADPKD | | details | Urine | Detected and Quantified | 74.192 +/- 41.507 umol/mmol creatinine | Children (1 - 13 years old) | Not Specified | Eosinophilic esophagitis | | details | Urine | Detected and Quantified | 31.7 +/- 6.5 umol/mmol creatinine | Adult (>18 years old) | Both | 3-Hydroxy-3- methylglutaryl-CoA lyase (HL) deficency | | details | Urine | Detected and Quantified | 39.7 +/- 0 umol/mmol creatinine | Adult (>18 years old) | Both | Propionic acidemia | | details | Urine | Detected and Quantified | 99.7 +/- 3.3 umol/mmol creatinine | Adult (>18 years old) | Both | Maple syrup urine disease | | details | Urine | Detected and Quantified | 51.9 +/- 0 umol/mmol creatinine | Adult (>18 years old) | Both | Aminoaciduria | | details | Urine | Detected and Quantified | 204-1600 umol/mmol creatinine | Newborn (0-30 days old) | Not Specified | Ethanolaminuria | | details |
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Associated Disorders and Diseases |
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Disease References | Irritable bowel syndrome |
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- Le Gall G, Noor SO, Ridgway K, Scovell L, Jamieson C, Johnson IT, Colquhoun IJ, Kemsley EK, Narbad A: Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome. J Proteome Res. 2011 Sep 2;10(9):4208-18. doi: 10.1021/pr2003598. Epub 2011 Aug 8. [PubMed:21761941 ]
| Ulcerative colitis |
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- Le Gall G, Noor SO, Ridgway K, Scovell L, Jamieson C, Johnson IT, Colquhoun IJ, Kemsley EK, Narbad A: Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome. J Proteome Res. 2011 Sep 2;10(9):4208-18. doi: 10.1021/pr2003598. Epub 2011 Aug 8. [PubMed:21761941 ]
| Colorectal cancer |
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- Brown DG, Rao S, Weir TL, O'Malia J, Bazan M, Brown RJ, Ryan EP: Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016 Jun 6;4:11. doi: 10.1186/s40170-016-0151-y. eCollection 2016. [PubMed:27275383 ]
- Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ: Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016. [PubMed:27015276 ]
- Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]
| Perillyl alcohol administration for cancer treatment |
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- Sugimoto M, Wong DT, Hirayama A, Soga T, Tomita M: Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics. 2010 Mar;6(1):78-95. Epub 2009 Sep 10. [PubMed:20300169 ]
| Pancreatic cancer |
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- Sugimoto M, Wong DT, Hirayama A, Soga T, Tomita M: Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics. 2010 Mar;6(1):78-95. Epub 2009 Sep 10. [PubMed:20300169 ]
| Periodontal disease |
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- Sugimoto M, Wong DT, Hirayama A, Soga T, Tomita M: Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics. 2010 Mar;6(1):78-95. Epub 2009 Sep 10. [PubMed:20300169 ]
| Autosomal dominant polycystic kidney disease |
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- Gronwald W, Klein MS, Zeltner R, Schulze BD, Reinhold SW, Deutschmann M, Immervoll AK, Boger CA, Banas B, Eckardt KU, Oefner PJ: Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine. Kidney Int. 2011 Jun;79(11):1244-53. doi: 10.1038/ki.2011.30. Epub 2011 Mar 9. [PubMed:21389975 ]
| Propionic acidemia |
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- Gronwald W, Klein MS, Kaspar H, Fagerer SR, Nurnberger N, Dettmer K, Bertsch T, Oefner PJ: Urinary metabolite quantification employing 2D NMR spectroscopy. Anal Chem. 2008 Dec 1;80(23):9288-97. doi: 10.1021/ac801627c. [PubMed:19551947 ]
| Maple syrup urine disease |
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- Gronwald W, Klein MS, Kaspar H, Fagerer SR, Nurnberger N, Dettmer K, Bertsch T, Oefner PJ: Urinary metabolite quantification employing 2D NMR spectroscopy. Anal Chem. 2008 Dec 1;80(23):9288-97. doi: 10.1021/ac801627c. [PubMed:19551947 ]
| Eosinophilic esophagitis |
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- (). Mordechai, Hien, and David S. Wishart. .
| Ethanolaminuria |
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- Cole DE, Farag S, Dooley KC: Ethanolaminuria: a non-specific laboratory finding in the seriously ill infant. Clin Biochem. 1988 Oct;21(5):297-300. [PubMed:3233740 ]
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Associated OMIM IDs | - 114500 (Colorectal cancer)
- 260350 (Pancreatic cancer)
- 170650 (Periodontal disease)
- 601313 (Autosomal dominant polycystic kidney disease)
- 606054 (Propionic acidemia)
- 248600 (Maple syrup urine disease)
- 610247 (Eosinophilic esophagitis)
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External Links |
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DrugBank ID | DB03994 |
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Phenol Explorer Compound ID | Not Available |
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FoodDB ID | FDB000769 |
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KNApSAcK ID | C00007279 |
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Chemspider ID | 13835336 |
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KEGG Compound ID | C00189 |
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BioCyc ID | ETHANOL-AMINE |
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BiGG ID | 34189 |
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Wikipedia Link | Ethanolamine |
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METLIN ID | 3207 |
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PubChem Compound | 700 |
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PDB ID | ETA |
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ChEBI ID | 16000 |
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References |
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Synthesis Reference | Soucaille, Philippe. Ethanolamine production by fermentation of genetically modified Escherichia coli. PCT Int. Appl. (2007), 23pp. |
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Material Safety Data Sheet (MSDS) | Download (PDF) |
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General References | - Engelborghs S, Marescau B, De Deyn PP: Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's disease. Neurochem Res. 2003 Aug;28(8):1145-50. [PubMed:12834252 ]
- Denissen JF, Grabowski BA, Johnson MK, Boyd SA, Uchic JT, Stein H, Cepa S, Hill P: The orally active renin inhibitor A-74273. In vivo and in vitro morpholine ring metabolism in rats, dogs, and humans. Drug Metab Dispos. 1994 Nov-Dec;22(6):880-8. [PubMed:7895605 ]
- Vance JE: Lipoproteins secreted by cultured rat hepatocytes contain the antioxidant 1-alk-1-enyl-2-acylglycerophosphoethanolamine. Biochim Biophys Acta. 1990 Jul 16;1045(2):128-34. [PubMed:2116174 ]
- Alberghina M, Giacchetto A, Cavallaro N: Levels of ethanolamine intermediates in the human and rat visual system structures: comparison with neural tissues of a lower vertebrate (Mustelus canis) and an invertebrate (Loligo pealei). Neurochem Int. 1993 Jan;22(1):45-51. [PubMed:8443564 ]
- Hammond EJ, Uthman BM, Wilder BJ, Ben-Menachem E, Hamberger A, Hedner T, Ekman R: Neurochemical effects of vagus nerve stimulation in humans. Brain Res. 1992 Jun 26;583(1-2):300-3. [PubMed:1504837 ]
- Perschak H, Amsler U, Vischer A, Siegfried J, Cuenod M: Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders. Hum Neurobiol. 1987;6(3):191-4. [PubMed:2896652 ]
- Renkonen O: Chromatographic separation of plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides. J Lipid Res. 1968 Jan;9(1):34-9. [PubMed:4295349 ]
- Ginsberg L, Rafique S, Xuereb JH, Rapoport SI, Gershfeld NL: Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain. Brain Res. 1995 Nov 6;698(1-2):223-6. [PubMed:8581486 ]
- Bluml S, Seymour KJ, Ross BD: Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain. Magn Reson Med. 1999 Oct;42(4):643-54. [PubMed:10502752 ]
- Farooqui AA, Rapoport SI, Horrocks LA: Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens. Neurochem Res. 1997 Apr;22(4):523-7. [PubMed:9130265 ]
- Mikhaevich IS, Vlasenkova NK, Gerasimova GK: Synergistic antiproliferative effect of cis-diammine-dichloroplatinum (II) and a new anticancer agent, plasmanyl-(N-acyl)-ethanolamine, an inhibitor of protein kinase C. Biomed Sci. 1991;2(6):659-64. [PubMed:1841636 ]
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