Showing metabocard for Propylene glycol (HMDB0001881)

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Gene Name:

AKR1B1

Uniprot ID:

P15121

Molecular weight:

35853.125

Reactions

General function:

Involved in protein-glutamine gamma-glutamyltransferase activity

Specific function:

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Gene Name:

F13A1

Uniprot ID:

P00488

Molecular weight:

83267.785

References

1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]

General function:

Not Available

Specific function:

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Gene Name:

AKR1B10

Uniprot ID:

O60218

Molecular weight:

Not Available

Reactions