Human Metabolome Database Version 3.5

Showing metabocard for Cytidine monophosphate (HMDB00095)

Record Information
Version 3.5
Creation Date 2005-11-16 08:48:42 -0700
Update Date 2013-05-29 13:24:45 -0600
HMDB ID HMDB00095
Secondary Accession Numbers None
Metabolite Identification
Common Name Cytidine monophosphate
Description Cytidine monophosphate, also known as 5'-cytidylic acid and abbreviated CMP, is a nucleotide. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine. Cytidine monophosphate (CMP) is derived from cytidine triphosphate (CTP) with subsequent loss of two phosphates. The synthesis of the pyrimidines CTP and UTP occurs in the cytoplasm and starts with the formation of carbamoyl phosphate from glutamine and CO2. Next, aspartate undergoes a condensation reaction with carbamoyl-phosphate to form orotic acid. In a subsequent cyclization reaction, the enzyme Aspartate carbamoyltransferase forms N-carbamoyl-aspartate which is converted into dihydroorotic acid by Dihydroorotase. The latter is converted to orotate by Dihydroorotate oxidase. Orotate is covalently linked with a phosphorylated ribosyl unit with Orotate phosphoribosyltransferase (aka "PRPP transferase") catalyzing reaction, yielding orotidine monophosphate (OMP). Orotidine-5-phosphate is decarboxylated by Orotidine-5'-phosphate decarboxylase to form uridine monophosphate (UMP). UMP is phosphorylated by two kinases to uridine triphosphate (UTP) via two sequential reactions with ATP. CTP is subsequently formed by amination of UTP by the catalytic activity of CTP synthetase. Cytosine monophosphate (CMP) and uridine monophosphate (UMP) have been prescribed for the treatment of neuromuscular affections in humans. Patients treated with CMP/UMP recover from altered neurological functions. Additionally, the administration of CMP/UMP appears to favour the entry of glucose in the muscle and CMP/UMP may be important in maintaining the level of hepatic glycogen constant during exercise. [PMID:18663991 Link_out].
Structure Thumb
Download: MOL | SDF | PDB | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. 5'-CMP
  2. 5-Cytidylate
  3. 5-Cytidylic acid
  4. CMP
  5. Cytidine 5'-monophosphate
  6. Cytidine 5'-monophosphorate
  7. Cytidine 5'-monophosphoric acid
  8. Cytidine 5'-phosphate
  9. Cytidine 5'-phosphorate
  10. Cytidine 5'-phosphoric acid
  11. Cytidine mono(dihydrogen phosphate)
  12. Cytidine monophosphate
  13. Cytidylate
  14. Cytidylic acid
Chemical Formula C9H14N3O8P
Average Molecular Weight 323.1965
Monoisotopic Molecular Weight 323.051850951
IUPAC Name {[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Traditional IUPAC Name [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid
CAS Registry Number 63-37-6
SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Identifier InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI Key IERHLVCPSMICTF-XVFCMESISA-N
Chemical Taxonomy
Kingdom Organic Compounds
Super Class Nucleosides, Nucleotides, and Analogues
Class Pyrimidine Nucleotides
Sub Class Pyrimidine Ribonucleotides
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
Substituents
  • 1,2 Diol
  • Aminopyrimidine
  • Glycosyl Compound
  • Hydropyrimidine
  • Monosaccharide Phosphate
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Oxolane
  • Pentose Monosaccharide
  • Phosphoric Acid Ester
  • Pyrimidine
  • Pyrimidone
  • Saccharide
  • Secondary Alcohol
Direct Parent Pyrimidine Ribonucleoside Monophosphates
Ontology
Status Expected and Not Quantified
Origin
  • Endogenous
Biofunction
  • Component of Ganglioside biosynthesis
  • Component of Globoside metabolism
  • Component of Glycerophospholipid metabolism
  • Component of Keratan sulfate biosynthesis
  • Component of N-Glycan biosynthesis
  • Component of O-Glycan biosynthesis
  • Component of Pyrimidine metabolism
Application Not Available
Cellular locations
  • Extracellular
  • Mitochondria
  • Nucleus
  • Lysosome
  • Golgi apparatus
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point 233 °C Not Available
Boiling Point Not Available Not Available
Water Solubility Not Available Not Available
LogP Not Available Not Available
Predicted Properties
Property Value Source
Water Solubility 16.3 g/L ALOGPS
LogP -2.05 ALOGPS
LogP -3.3 ChemAxon
LogS -1.30 ALOGPS
pKa (strongest acidic) 1.23 ChemAxon
pKa (strongest basic) -0.62 ChemAxon
Hydrogen Acceptor Count 9 ChemAxon
Hydrogen Donor Count 5 ChemAxon
Polar Surface Area 175.14 A2 ChemAxon
Rotatable Bond Count 4 ChemAxon
Refractivity 65.42 ChemAxon
Polarizability 26.89 ChemAxon
Formal Charge 0 ChemAxon
Physiological Charge -2 ChemAxon
Spectra
1H NMR Spectrum
MS/MS Spectrum Quattro_QQQ 10
MS/MS Spectrum Quattro_QQQ 25
MS/MS Spectrum Quattro_QQQ 40
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
[1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations
  • Extracellular
  • Mitochondria
  • Nucleus
  • Lysosome
  • Golgi apparatus
Biofluid Locations Not Available
Tissue Location
  • All Tissues
  • Prostate
Pathways
Name SMPDB Link KEGG Link
Pyrimidine Metabolism SMP00046 map00240 Link_out
Transcription/Translation SMP00019 Not Available
Phosphatidylinositol Phosphate Metabolism SMP00463 map00562 Link_out
Plasmalogen Synthesis SMP00479 Not Available
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease References None
Associated OMIM IDs None
DrugBank ID Not Available
DrugBank Metabolite ID Not Available
Phenol Explorer Compound ID Not Available
Phenol Explorer Metabolite ID Not Available
FoodDB ID FDB011882
KNApSAcK ID Not Available
Chemspider ID 5901 Link_out
KEGG Compound ID C00055 Link_out
BioCyc ID CMP Link_out
BiGG ID 33689 Link_out
Wikipedia Link Cytidine monophosphate Link_out
NuGOwiki Link HMDB00095 Link_out
Metagene Link HMDB00095 Link_out
METLIN ID 5143 Link_out
PubChem Compound 6131 Link_out
PDB ID C Link_out
ChEBI ID 17361 Link_out
References
Synthesis Reference Zhou, Jingkang. Method for preparing cytidine 5'-monophosphate. Faming Zhuanli Shenqing Gongkai Shuomingshu (2005), 12 pp.
Material Safety Data Sheet (MSDS) Download (PDF)
General References
  1. Hirono A, Fujii H, Miyajima H, Kawakatsu T, Hiyoshi Y, Miwa S: Three families with hereditary hemolytic anemia and pyrimidine 5'-nucleotidase deficiency: electrophoretic and kinetic studies. Clin Chim Acta. 1983 May 30;130(2):189-97. Pubmed: 6307548 Link_out
  2. Okahira S, Nishikawa F, Nishikawa S, Akazawa T, Seya T, Matsumoto M: Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure. DNA Cell Biol. 2005 Oct;24(10):614-23. Pubmed: 16225392 Link_out
  3. Daunter B, Newlands J: Seminal plasma biochemistry II: seminal plasma and spermatozoal cytidine monophosphate-sialic acid synthetase and sialyltransferase activities. Andrologia. 1981 May-Jun;13(3):215-24. Pubmed: 6267956 Link_out
  4. Schmukler M, Jewett PB, Levy CC: The effects of polyamines on a residue-specific human plasma ribonuclease. J Biol Chem. 1975 Mar 25;250(6):2206-12. Pubmed: 234961 Link_out
  5. Paglia DE, Valentine WN, Keitt AS, Brockway RA, Nakatani M: Pyrimidine nucleotidase deficiency with active dephosphorylation of dTMP: evidence for existence of thymidine nucleotidase in human erythrocytes. Blood. 1983 Nov;62(5):1147-9. Pubmed: 6313098 Link_out
  6. Yates AJ, Warner JK: Behavior of sugar derivatives in procedures for ganglioside isolation. Lipids. 1984 Jul;19(7):562-9. Pubmed: 6748871 Link_out
  7. Li YP, Curley G, Lopez M, Chavez M, Glew R, Aragon A, Kumar H, Baca OG: Protein-tyrosine phosphatase activity of Coxiella burnetii that inhibits human neutrophils. Acta Virol. 1996 Nov-Dec;40(5-6):263-72. Pubmed: 9171454 Link_out
  8. Hirono A, Fujii H, Natori H, Kurokawa I, Miwa S: Chromatographic analysis of human erythrocyte pyrimidine 5'-nucleotidase from five patients with pyrimidine 5'-nucleotidase deficiency. Br J Haematol. 1987 Jan;65(1):35-41. Pubmed: 3028466 Link_out
  9. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. Pubmed: 19212411 Link_out
  10. Gella A, Ponce J, Cusso R, Durany N: Effect of the nucleotides CMP and UMP on exhaustion in exercise rats. J Physiol Biochem. 2008 Mar;64(1):9-17. Pubmed: 18663991 Link_out

Enzymes
Name: 5'-nucleotidase
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5E
Uniprot ID: P21589 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: UMP-CMP kinase
Reactions:
Adenosine triphosphate + Cytidine monophosphate unknown ADP + CDP details
Gene Name: CMPK1
Uniprot ID: P30085 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 1B
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5C1B
Uniprot ID: Q96P26 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 1A
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5C1A
Uniprot ID: Q9BXI3 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, cytosolic type
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5C
Uniprot ID: Q8TCD5 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, mitochondrial
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5M
Uniprot ID: Q9NPB1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 1
Reactions:
CDP + Water unknown Cytidine monophosphate + Phosphoric acid details
Gene Name: ENTPD1
Uniprot ID: P49961 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Soluble calcium-activated nucleotidase 1
Reactions: Not Available
Gene Name: CANT1
Uniprot ID: Q8WVQ1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 3
Reactions:
CDP + Water unknown Cytidine monophosphate + Phosphoric acid details
Gene Name: ENTPD3
Uniprot ID: O75355 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Uridine-cytidine kinase 1
Reactions:
Adenosine triphosphate + Cytidine unknown ADP + Cytidine monophosphate details
Uridine triphosphate + Cytidine unknown Uridine 5'-diphosphate + Cytidine monophosphate details
Guanosine triphosphate + Cytidine unknown Guanosine diphosphate + Cytidine monophosphate details
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphate details
Deoxyadenosine triphosphate + Cytidine unknown dADP + Cytidine monophosphate details
dGTP + Cytidine unknown dGDP + Cytidine monophosphate details
Thymidine 5'-triphosphate + Cytidine unknown dTDP + Cytidine monophosphate details
dCTP + Cytidine unknown dCDP + Cytidine monophosphate details
Deoxyuridine triphosphate + Cytidine unknown dUDP + Cytidine monophosphate details
Gene Name: UCK1
Uniprot ID: Q9HA47 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein details
Gene Name: ST3GAL3
Uniprot ID: Q11203 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R details
Gene Name: ST8SIA1
Uniprot ID: Q92185 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: N-acylneuraminate cytidylyltransferase
Reactions: Not Available
Gene Name: CMAS
Uniprot ID: Q8NFW8 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Phosphatidylcholine:ceramide cholinephosphotransferase 2
Reactions: Not Available
Gene Name: SGMS2
Uniprot ID: Q8NHU3 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Reactions:
CDP-diacylglycerol + Myoinositol unknown Cytidine monophosphate + phosphatidyl-1D-myo-inositol details
CDP-diacylglycerol + Myoinositol unknown Cytidine monophosphate + 1-Phosphatidyl-D-myo-inositol details
Gene Name: CDIPT
Uniprot ID: O14735 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Lactosylceramide alpha-2,3-sialyltransferase
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide details
Gene Name: ST3GAL5
Uniprot ID: Q9UNP4 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Type 2 lactosamine alpha-2,3-sialyltransferase
Reactions: Not Available
Gene Name: ST3GAL6
Uniprot ID: Q9Y274 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Phosphatidylcholine:ceramide cholinephosphotransferase 1
Reactions: Not Available
Gene Name: SGMS1
Uniprot ID: Q86VZ5 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R details
Gene Name: ST3GAL1
Uniprot ID: Q11201 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Uridine-cytidine kinase 2
Reactions:
Adenosine triphosphate + Cytidine unknown ADP + Cytidine monophosphate details
Uridine triphosphate + Cytidine unknown Uridine 5'-diphosphate + Cytidine monophosphate details
Guanosine triphosphate + Cytidine unknown Guanosine diphosphate + Cytidine monophosphate details
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphate details
Deoxyadenosine triphosphate + Cytidine unknown dADP + Cytidine monophosphate details
dGTP + Cytidine unknown dGDP + Cytidine monophosphate details
Thymidine 5'-triphosphate + Cytidine unknown dTDP + Cytidine monophosphate details
dCTP + Cytidine unknown dCDP + Cytidine monophosphate details
Deoxyuridine triphosphate + Cytidine unknown dUDP + Cytidine monophosphate details
Gene Name: UCK2
Uniprot ID: Q9BZX2 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cholinephosphotransferase 1
Reactions:
Citicoline + 1,2-diacylglycerol unknown Cytidine monophosphate + a phosphatidylcholine details
Citicoline + 1,2-Diacyl-sn-glycerol unknown Cytidine monophosphate + Phosphatidylcholine details
Citicoline + 1-Alkyl-2-acetyl-sn-glycerol unknown Cytidine monophosphate + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine details
CMP-N-trimethyl-2-aminoethylphosphonate + Diacylglycerol unknown Cytidine monophosphate + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate details
1-Alkyl-2-acylglycerol + Citicoline unknown 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + Cytidine monophosphate details
Gene Name: CHPT1
Uniprot ID: Q8WUD6 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Phosphopantothenate--cysteine ligase
Reactions:
Cytidine triphosphate + D-4'-Phosphopantothenate + L-Cysteine unknown Cytidine monophosphate + Pyrophosphate + N-((R)-4'-phosphopantothenoyl)-L-cysteine details
Cytidine triphosphate + D-4'-Phosphopantothenate + L-Cysteine unknown Cytidine monophosphate + Pyrophosphate + 4-Phosphopantothenoylcysteine details
Gene Name: PPCS
Uniprot ID: Q9HAB8 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein details
Gene Name: ST3GAL4
Uniprot ID: Q11206 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 3
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5C3
Uniprot ID: Q9H0P0 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Choline/ethanolaminephosphotransferase 1
Reactions:
CDP-Ethanolamine + 1,2-diacylglycerol unknown Cytidine monophosphate + a phosphatidylethanolamine details
Citicoline + 1,2-diacylglycerol unknown Cytidine monophosphate + a phosphatidylcholine details
Citicoline + 1,2-Diacyl-sn-glycerol unknown Cytidine monophosphate + Phosphatidylcholine details
CDP-Ethanolamine + 1,2-Diacyl-sn-glycerol unknown Cytidine monophosphate + Phosphatidylethanolamine details
Citicoline + 1-Alkyl-2-acetyl-sn-glycerol unknown Cytidine monophosphate + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine details
CMP-2-aminoethylphosphonate + Diacylglycerol unknown Cytidine monophosphate + Diacylglyceryl-2-aminoethylphosphonate details
CMP-N-trimethyl-2-aminoethylphosphonate + Diacylglycerol unknown Cytidine monophosphate + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate details
CDP-Ethanolamine + 1-Alkyl-2-acylglycerol unknown Cytidine monophosphate + 1-Alkyl-2-acylglycerophosphoethanolamine details
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Cytidine monophosphate unknown 1-Alkenyl-2-acylglycerol + CDP-Ethanolamine details
1-Alkyl-2-acylglycerol + Citicoline unknown 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + Cytidine monophosphate details
Gene Name: CEPT1
Uniprot ID: Q9Y6K0 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
Reactions:
CDP-diacylglycerol + Glycerol 3-phosphate unknown Cytidine monophosphate + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate details
CDP-diacylglycerol + Glycerol 3-phosphate unknown Cytidine monophosphate + Phosphatidylglycerophosphate details
Gene Name: PGS1
Uniprot ID: Q32NB8 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic purine 5'-nucleotidase
Reactions:
Cytidine monophosphate + Water unknown Cytidine + Phosphoric acid details
Gene Name: NT5C2
Uniprot ID: P49902 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ethanolaminephosphotransferase 1
Reactions:
CDP-Ethanolamine + 1,2-diacylglycerol unknown Cytidine monophosphate + a phosphatidylethanolamine details
CDP-Ethanolamine + 1,2-Diacyl-sn-glycerol unknown Cytidine monophosphate + Phosphatidylethanolamine details
CMP-2-aminoethylphosphonate + Diacylglycerol unknown Cytidine monophosphate + Diacylglyceryl-2-aminoethylphosphonate details
CDP-Ethanolamine + 1-Alkyl-2-acylglycerol unknown Cytidine monophosphate + 1-Alkyl-2-acylglycerophosphoethanolamine details
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Cytidine monophosphate unknown 1-Alkenyl-2-acylglycerol + CDP-Ethanolamine details
Gene Name: EPT1
Uniprot ID: Q9C0D9 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: UMP-CMP kinase 2, mitochondrial
Reactions:
Adenosine triphosphate + Cytidine monophosphate unknown ADP + CDP details
Gene Name: CMPK2
Uniprot ID: Q5EBM0 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Uridine-cytidine kinase-like 1
Reactions:
Adenosine triphosphate + Cytidine unknown ADP + Cytidine monophosphate details
Uridine triphosphate + Cytidine unknown Uridine 5'-diphosphate + Cytidine monophosphate details
Guanosine triphosphate + Cytidine unknown Guanosine diphosphate + Cytidine monophosphate details
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphate details
Deoxyadenosine triphosphate + Cytidine unknown dADP + Cytidine monophosphate details
dGTP + Cytidine unknown dGDP + Cytidine monophosphate details
Thymidine 5'-triphosphate + Cytidine unknown dTDP + Cytidine monophosphate details
dCTP + Cytidine unknown dCDP + Cytidine monophosphate details
Deoxyuridine triphosphate + Cytidine unknown dUDP + Cytidine monophosphate details
Gene Name: UCKL1
Uniprot ID: Q9NWZ5 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 8
Reactions:
CDP + Water unknown Cytidine monophosphate + Phosphoric acid details
Gene Name: ENTPD8
Uniprot ID: Q5MY95 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R unknown Cytidine monophosphate + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-(N-acetyl-alpha-neuraminyl-(2->6))-N-acetyl-D-galactosaminyl-R details
Gene Name: ST6GALNAC4
Uniprot ID: Q9H4F1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Reactions:
Citicoline + Water unknown Cytidine monophosphate + Phosphorylcholine details
CDP-glycerol + Water unknown Cytidine monophosphate + Glycerol 3-phosphate details
Gene Name: ADPRM
Uniprot ID: Q3LIE5 Link_out
Protein Sequence: FASTA
Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R details
Gene Name: ST3GAL2
Uniprot ID: Q16842 Link_out
Protein Sequence: FASTA
Name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein unknown Cytidine monophosphate + glycano-((2->6)-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein details
Gene Name: ST6GALNAC1
Uniprot ID: Q9NSC7 Link_out
Protein Sequence: FASTA
Name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + glycano-beta-D-galactosyl-1,3-(N-acetyl-D-galactosaminyl)-glycoprotein unknown Cytidine monophosphate + glycano-beta-D-galactosyl-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein details
Gene Name: ST6GALNAC2
Uniprot ID: Q9UJ37 Link_out
Protein Sequence: FASTA
Name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(N-acetyl-D-galactosaminyl)-glycoprotein unknown Cytidine monophosphate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein details
Gene Name: ST6GALNAC3
Uniprot ID: Q8NDV1 Link_out
Protein Sequence: FASTA
Name: Beta-galactoside alpha-2,6-sialyltransferase 1
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine unknown Cytidine monophosphate + (N-acetylneuraminosyl(a2-6)lactosamine) details
Gene Name: ST6GAL1
Uniprot ID: P15907 Link_out
Protein Sequence: FASTA
Name: Beta-galactoside alpha-2,6-sialyltransferase 2
Reactions:
Cytidine monophosphate N-acetylneuraminic acid + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine unknown Cytidine monophosphate + (N-acetylneuraminosyl(a2-6)lactosamine) details
Gene Name: ST6GAL2
Uniprot ID: Q96JF0 Link_out
Protein Sequence: FASTA