Record Information
Version3.6
Creation Date2005-11-16 15:48:42 UTC
Update Date2013-02-09 00:08:10 UTC
HMDB IDHMDB00250
Secondary Accession NumbersNone
Metabolite Identification
Common NamePyrophosphate
DescriptionIn chemistry, the anion, the salts, and the esters of pyrophosphoric acid are called pyrophosphates. The anion is abbreviated PPi and is formed by the hydrolysis of ATP into AMP in cells. This hydrolysis is called pyrophosphorolysis. The pyrophosphate anion has the structure P2O74-, and is an acid anhydride of phosphate. It is unstable in aqueous solution and rapidly hydrolyzes into inorganic phosphate.
Structure
Thumb
Synonyms
  1. (4-)Diphosphoric acid ion
  2. (P2O74-)Diphosphate
  3. Diphosphate
  4. Diphosphoric acid
  5. PPi
  6. Pyrometaphosphate
  7. Pyrophosphate
  8. Pyrophosphate tetraanion
  9. Pyrophosphate(4-) ion
Chemical FormulaO7P2
Average Molecular Weight173.9433
Monoisotopic Molecular Weight173.911925378
IUPAC Name(phosphonatooxy)phosphonate
Traditional IUPAC Namephosphonatooxyphosphonate
CAS Registry Number14000-31-8
SMILES
[O-]P([O-])(=O)OP([O-])([O-])=O
InChI Identifier
InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4
InChI KeyXPPKVPWEQAFLFU-UHFFFAOYSA-J
Chemical Taxonomy
KingdomInorganic Compounds
Super ClassHomogeneous Non-metal Compounds
ClassNon-metal Oxoanionic Compounds
Sub ClassNon-metal Pyrophosphates
Other Descriptors
  • phosphorus oxoanion(ChEBI)
Substituents
  • N/A
Direct ParentNon-metal Pyrophosphates
Ontology
StatusDetected and Quantified
Origin
  • Endogenous
Biofunction
  • Component of Alanine and aspartate metabolism
  • Component of Aminoacyl-tRNA biosynthesis
  • Component of Aminophosphonate metabolism
  • Component of Aminosugars metabolism
  • Component of Arginine and proline metabolism
  • Component of Biotin metabolism
  • Component of Fatty acid metabolism
  • Component of Folate biosynthesis
  • Component of Fructose and mannose metabolism
  • Component of Galactose metabolism
  • Component of Glutamate metabolism
  • Component of Glycerophospholipid metabolism
  • Component of Glycine, serine and threonine metabolism
  • Component of Histidine metabolism
  • Component of Lysine biosynthesis
  • Component of Methionine metabolism
  • Component of Nicotinate and nicotinamide metabolism
  • Component of Nitrogen metabolism
  • Component of Nucleotide sugars metabolism
  • Component of Phenylalanine, tyrosine and tryptophan biosynthesis
  • Component of Porphyrin and chlorophyll metabolism
  • Component of Propanoate metabolism
  • Component of Purine metabolism
  • Component of Pyrimidine metabolism
  • Component of Pyruvate metabolism
  • Component of Selenoamino acid metabolism
  • Component of Starch and sucrose metabolism
  • Component of Sulfur metabolism
  • Component of Terpenoid biosynthesis
  • Component of Tryptophan metabolism
  • Component of Valine, leucine and isoleucine biosynthesis
ApplicationNot Available
Cellular locations
  • Cytoplasm
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Peroxisome
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point61 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-1.4ChemAxon
pKa (strongest acidic)1.7ChemAxon
physiological charge-3ChemAxon
hydrogen acceptor count6ChemAxon
hydrogen donor count0ChemAxon
polar surface area135.61ChemAxon
rotatable bond count2ChemAxon
refractivity21.04ChemAxon
polarizability9.03ChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Peroxisome
Biofluid Locations
  • Blood
  • Urine
Tissue Location
  • Epidermis
  • Fibroblasts
  • Intestine
  • Neuron
  • Platelet
  • Prostate
  • Skeletal Muscle
  • Testes
Pathways
NameSMPDB LinkKEGG Link
Transcription/TranslationSMP00019Not Available
Normal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified1.8 (0.64-2.96) uMAdult (>18 years old)BothNormal
  • Geigy Scient...
UrineDetected and Quantified2.56 +/- 1.22 umol/mmol creatinineChildren (1-13 year old)BothNormal
  • Geigy Scient...
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB021918
KNApSAcK IDNot Available
Chemspider ID559142
KEGG Compound IDC00013
BioCyc IDPPI
BiGG ID33511
Wikipedia LinkPyrophosphate
NuGOwiki LinkHMDB00250
Metagene LinkHMDB00250
METLIN ID3306
PubChem Compound644102
PDB IDDPO
ChEBI ID18361
References
Synthesis ReferenceDittmer, Donald C.; Silverstein, V. Opshelor. Production of pyrophosphate from S-n-butyl phosphorothioate. Journal of Organic Chemistry (1961), 26 4706-7.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Kosoglou T, Statkevich P, Johnson-Levonas AO, Paolini JF, Bergman AJ, Alton KB: Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. Clin Pharmacokinet. 2005;44(5):467-94. Pubmed: 15871634
  2. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. Pubmed: 19212411
  3. Broll H: [Effect of chloroquine diphosphate on the superhelix structure of DNA and protein synthesis in synovial cells in chronic polyarthritis] Wien Klin Wochenschr. 1983 Dec 23;95(24):877-80. Pubmed: 6670282
  4. Golanski J, Pluta J, Baraniak J, Watala C: Limited usefulness of the PFA-100 for the monitoring of ADP receptor antagonists--in vitro experience. Clin Chem Lab Med. 2004 Jan;42(1):25-9. Pubmed: 15061376
  5. Mateos-Trigos G, Evans RJ, Heath MF: Effects of P2Y(1) and P2Y(12) receptor antagonists on ADP-induced shape change of equine platelets: comparison with human platelets. Platelets. 2002 Aug-Sep;13(5-6):285-92. Pubmed: 12189014
  6. Sirkis SI: [Serum and cerebrospinal fluid enzyme spectra in meningitis and their differential diagnostic value] Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(2):193-7. Pubmed: 7072418
  7. Barbier O, Torra IP, Sirvent A, Claudel T, Blanquart C, Duran-Sandoval D, Kuipers F, Kosykh V, Fruchart JC, Staels B: FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. Gastroenterology. 2003 Jun;124(7):1926-40. Pubmed: 12806625
  8. March JG, Simonet BM, Grases F: Determination of pyrophosphate in renal calculi and urine by means of an enzymatic method. Clin Chim Acta. 2001 Dec;314(1-2):187-94. Pubmed: 11718694
  9. Namiki M, Kitamura M, Nonomura N, Sugao H, Nakamura M, Okuyama A, Utsunomiya M, Itatani H, Matsumoto K, Sonoda T: Direct inhibitory effect of estrogen on the human testis in vitro. Arch Androl. 1988;20(2):131-5. Pubmed: 3395157
  10. Pickett DA, Welch DF: Recognition of Staphylococcus saprophyticus in urine cultures by screening colonies for production of phosphatase. J Clin Microbiol. 1985 Mar;21(3):310-3. Pubmed: 2984240
  11. Hua HT, Albadawi H, Entabi F, Conrad M, Stoner MC, Meriam BT, Sroufe R, Houser S, Lamuraglia GM, Watkins MT: Polyadenosine diphosphate-ribose polymerase inhibition modulates skeletal muscle injury following ischemia reperfusion. Arch Surg. 2005 Apr;140(4):344-51; discussion 351-2. Pubmed: 15837884
  12. Dahlmann N, Ueckermann C: Separation of deoxythymidine-5'-triphosphatase from unspecific hydrolases. A recommended micromethod in the diagnostic evaluation of human carcinoma. Anticancer Res. 1984 Jul-Oct;4(4-5):299-303. Pubmed: 6091528
  13. Ebadi M, Sharma SK, Ghafourifar P, Brown-Borg H, El Refaey H: Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins. Methods Enzymol. 2005;396:276-98. Pubmed: 16291239
  14. Tallaksen CM, Sande A, Bohmer T, Bell H, Karlsen J: Kinetics of thiamin and thiamin phosphate esters in human blood, plasma and urine after 50 mg intravenously or orally. Eur J Clin Pharmacol. 1993;44(1):73-8. Pubmed: 8436160
  15. Zhong D, Meins J, Scheidel B, Blume H: [Development of an HPLC method for determination of chloroquine in plasma] Pharmazie. 1993 May;48(5):349-52. Pubmed: 8327563
  16. Recio JA, Paez JG, Maskeri B, Loveland M, Velasco JA, Notario V: Both normal and transforming PCPH proteins have guanosine diphosphatase activity but only the oncoprotein cooperates with Ras in activating extracellular signal-regulated kinase ERK1. Cancer Res. 2000 Mar 15;60(6):1720-8. Pubmed: 10749145
  17. Puri RN, Colman RF, Colman RW: Modulation of platelet responses by 2-[3-(bromo-2-oxopropylthio)]adenosine-5'-diphosphate involves its binding to as well as covalent modification of an ADP-receptor, aggregin. Arch Biochem Biophys. 1997 Jul 1;343(1):140-5. Pubmed: 9210656
  18. Hamagishi Y, Oki T, Tone H, Inui T: A radioimmunoassay for guanosine-5'-diphosphate-3'-diphosphate and adenosine-5'-triphosphate-3'-diphosphate. J Biochem (Tokyo). 1980 Dec;88(6):1785-92. Pubmed: 6780546
  19. Lee AY, Youm YH, Kim NH, Yang H, Choi WI: Keratinocytes in the depigmented epidermis of vitiligo are more vulnerable to trauma (suction) than keratinocytes in the normally pigmented epidermis, resulting in their apoptosis. Br J Dermatol. 2004 Nov;151(5):995-1003. Pubmed: 15541077
  20. Ito H, Yamamoto H, Kimura Y, Kambe H, Okochi T, Kishimoto S: Affinity chromatography of human plasma gelsolin with polyphosphate compounds on immobilized Cibacron Blue F3GA. J Chromatogr. 1990 Apr 6;526(2):397-406. Pubmed: 2163407

Only showing the first 50 proteins. There are 351 proteins in total.

Enzymes

Gene Name:
ACSS2
Uniprot ID:
Q9NR19
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Adenosine triphosphate + Acetic acid unknown Pyrophosphate + Acetyl adenylatedetails
Adenosine triphosphate + Propionic acid unknown Pyrophosphate + Propinol adenylatedetails
Gene Name:
ACSS1
Uniprot ID:
Q9NUB1
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Adenosine triphosphate + Acetic acid unknown Pyrophosphate + Acetyl adenylatedetails
Adenosine triphosphate + Propionic acid unknown Pyrophosphate + Propinol adenylatedetails
Gene Name:
PON3
Uniprot ID:
Q15166
Gene Name:
FPGT
Uniprot ID:
O14772
Reactions
Guanosine triphosphate + Fucose 1-phosphate unknown Pyrophosphate + GDP-L-fucosedetails
Gene Name:
FDFT1
Uniprot ID:
P37268
Reactions
Farnesyl pyrophosphate + NAD(P)H unknown Squalene + Pyrophosphate + NAD(P)(+)details
Farnesyl pyrophosphate unknown Pyrophosphate + Presqualene diphosphatedetails
Presqualene diphosphate + NADPH + Hydrogen Ion unknown Pyrophosphate + Squalene + NADPdetails
Farnesyl pyrophosphate + NADPH + Hydrogen Ion unknown Squalene + Pyrophosphate + NADPdetails
Gene Name:
FARSA
Uniprot ID:
Q9Y285
Reactions
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)details
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)details
Gene Name:
FARS2
Uniprot ID:
O95363
Reactions
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)details
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)details
Gene Name:
ALDH7A1
Uniprot ID:
P49419
Reactions
Aminoadipic acid + Adenosine triphosphate unknown L-2-Aminoadipate adenylate + Pyrophosphatedetails
Gene Name:
PPAT
Uniprot ID:
Q06203
Reactions
5-Phosphoribosylamine + Pyrophosphate + L-Glutamic acid unknown L-Glutamine + Phosphoribosyl pyrophosphate + Waterdetails
Gene Name:
NMNAT1
Uniprot ID:
Q9HAN9
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
NMNAT3
Uniprot ID:
Q96T66
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
QPRT
Uniprot ID:
Q15274
Reactions
nicotinate beta-D-ribonucleotide + Pyrophosphate + CO(2) unknown Quinolinic acid + Phosphoribosyl pyrophosphatedetails
nicotinate beta-D-ribonucleotide + Pyrophosphate + Carbon dioxide unknown Quinolinic acid + Phosphoribosyl pyrophosphatedetails
Gene Name:
NMNAT2
Uniprot ID:
Q9BZQ4
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
PAPSS1
Uniprot ID:
O43252
Reactions
Adenosine triphosphate + Oat gum unknown Pyrophosphate + Adenosine phosphosulfatedetails
Adenosine triphosphate + Selenocystathionine unknown Pyrophosphate + Adenylylselenatedetails
Gene Name:
PAPSS2
Uniprot ID:
O95340
Reactions
Adenosine triphosphate + Oat gum unknown Pyrophosphate + Adenosine phosphosulfatedetails
Adenosine triphosphate + Selenocystathionine unknown Pyrophosphate + Adenylylselenatedetails
Gene Name:
CMAS
Uniprot ID:
Q8NFW8
Reactions
Cytidine triphosphate + N-acylneuraminate unknown Pyrophosphate + Cytidine monophosphate N-acetylneuraminic aciddetails
Cytidine triphosphate + N-Acetylneuraminic acid unknown Pyrophosphate + Cytidine monophosphate N-acetylneuraminic aciddetails
Cytidine triphosphate + N-Glycolylneuraminic acid unknown Pyrophosphate + CMP-N-glycoloylneuraminatedetails
Gene Name:
MAT2A
Uniprot ID:
P31153
Reactions
Adenosine triphosphate + L-Methionine + Water unknown Phosphoric acid + Pyrophosphate + S-Adenosylmethioninedetails
Phosphoric acid + Pyrophosphate + S-Adenosylmethionine unknown Adenosine triphosphate + L-Methionine + Waterdetails
Adenosine triphosphate + Selenomethionine + Water unknown Phosphoric acid + Pyrophosphate + Se-Adenosylselenomethioninedetails
Gene Name:
MAT1A
Uniprot ID:
Q00266
Reactions
Adenosine triphosphate + L-Methionine + Water unknown Phosphoric acid + Pyrophosphate + S-Adenosylmethioninedetails
Phosphoric acid + Pyrophosphate + S-Adenosylmethionine unknown Adenosine triphosphate + L-Methionine + Waterdetails
Adenosine triphosphate + Selenomethionine + Water unknown Phosphoric acid + Pyrophosphate + Se-Adenosylselenomethioninedetails
Gene Name:
ITPA
Uniprot ID:
Q9BY32
Reactions
A nucleoside triphosphate + Water unknown a nucleotide + Pyrophosphatedetails
Guanosine triphosphate + Water unknown Guanosine monophosphate + Pyrophosphatedetails
Uridine triphosphate + Water unknown Uridine 5'-monophosphate + Pyrophosphatedetails
Inosine triphosphate + Water unknown Inosinic acid + Pyrophosphatedetails
dGTP + Water unknown 2'-Deoxyguanosine 5'-monophosphate + Pyrophosphatedetails
Deoxyuridine triphosphate + Water unknown dUMP + Pyrophosphatedetails
Xanthosine 5-triphosphate + Water unknown Xanthylic acid + Pyrophosphatedetails
2'-Deoxyinosine triphosphate + Water unknown dIMP + Pyrophosphatedetails
6-Mercaptopurine ribonucleoside triphosphate + Water unknown 6-Thioinosine-5'-monophosphate + Pyrophosphatedetails
Gene Name:
DUT
Uniprot ID:
P33316
Reactions
Deoxyuridine triphosphate + Water unknown dUMP + Pyrophosphatedetails
Gene Name:
APRT
Uniprot ID:
P07741
Reactions
Adenosine monophosphate + Pyrophosphate unknown Adenine + Phosphoribosyl pyrophosphatedetails
Guanosine monophosphate + Pyrophosphate unknown Guanine + Phosphoribosyl pyrophosphatedetails
AICAR + Pyrophosphate unknown 5-Aminoimidazole-4-carboxamide + Phosphoribosyl pyrophosphatedetails
Gene Name:
HPRT1
Uniprot ID:
P00492
Reactions
Inosinic acid + Pyrophosphate unknown Hypoxanthine + Phosphoribosyl pyrophosphatedetails
Guanosine monophosphate + Pyrophosphate unknown Guanine + Phosphoribosyl pyrophosphatedetails
Adenosine monophosphate + Pyrophosphate unknown Adenine + Phosphoribosyl pyrophosphatedetails
Xanthylic acid + Pyrophosphate unknown Xanthine + Phosphoribosyl pyrophosphatedetails
Mercaptopurine + Phosphoribosyl pyrophosphate unknown 6-Thioinosine-5'-monophosphate + Pyrophosphatedetails
6-Methylmercaptopurine + Phosphoribosyl pyrophosphate unknown 6-Methylthiopurine 5'-monophosphate ribonucleotide + Pyrophosphatedetails
Thioguanine + Phosphoribosyl pyrophosphate unknown 6-Thioguanosine monophosphate + Pyrophosphatedetails
Gene Name:
HLCS
Uniprot ID:
P50747
Reactions
Adenosine triphosphate + Biotin + apo-[methylmalonyl-CoA:pyruvate carboxytransferase] unknown Adenosine monophosphate + Pyrophosphate + [methylmalonyl-CoA:pyruvate carboxytransferase]details
Adenosine triphosphate + Biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] unknown Adenosine monophosphate + Pyrophosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)]details
Adenosine triphosphate + Biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] unknown Adenosine monophosphate + Pyrophosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)]details
Adenosine triphosphate + Biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] unknown Adenosine monophosphate + Pyrophosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)]details
Adenosine triphosphate + Biotin unknown Pyrophosphate + Biotinyl-5'-AMPdetails
Gene Name:
FARSB
Uniprot ID:
Q9NSD9
Reactions
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)details
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)details
Gene Name:
UBE2A
Uniprot ID:
P49459
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
UBE2M
Uniprot ID:
P61081
Reactions
Adenosine triphosphate + NEDD8 + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-NEDD8yllysinedetails
Gene Name:
UBE2L6
Uniprot ID:
O14933
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
GARS
Uniprot ID:
P41250
Reactions
Adenosine triphosphate + Glycine + tRNA(Gly) unknown Adenosine monophosphate + Pyrophosphate + glycyl-tRNA(Gly)details
Adenosine triphosphate + Glycine + tRNA(Gly) unknown Adenosine monophosphate + Pyrophosphate + Glycyl-tRNA(Gly)details
Gene Name:
EPRS
Uniprot ID:
P07814
Reactions
Adenosine triphosphate + L-Glutamic acid + tRNA(Glu) unknown Adenosine monophosphate + Pyrophosphate + L-glutamyl-tRNA(Glu)details
Adenosine triphosphate + L-Proline + tRNA(Pro) unknown Adenosine monophosphate + Pyrophosphate + L-prolyl-tRNA(Pro)details
Adenosine triphosphate + L-Proline + tRNA(Pro) unknown Adenosine monophosphate + Pyrophosphate + L-Prolyl-tRNA(Pro)details
tRNA(Glu) + L-Glutamic acid + Adenosine triphosphate unknown L-Glutamyl-tRNA(Glu) + Pyrophosphate + Adenosine monophosphatedetails
Gene Name:
ACSL4
Uniprot ID:
O60488
Reactions
Adenosine triphosphate + a long-chain fatty acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + an acyl-CoAdetails
Adenosine triphosphate + Palmitic acid + Coenzyme A unknown Adenosine monophosphate + hexadecanoyl-CoA + Pyrophosphatedetails
Gene Name:
UBE2D1
Uniprot ID:
P51668
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
WARS
Uniprot ID:
P23381
Reactions
Adenosine triphosphate + L-Tryptophan + tRNA(Trp) unknown Adenosine monophosphate + Pyrophosphate + L-tryptophyl-tRNA(Trp)details
Adenosine triphosphate + L-Tryptophan + tRNA(Trp) unknown Adenosine monophosphate + Pyrophosphate + L-Tryptophanyl-tRNA(Trp)details
Gene Name:
ACSL1
Uniprot ID:
P33121
Reactions
Adenosine triphosphate + a long-chain fatty acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + an acyl-CoAdetails
Adenosine triphosphate + Palmitic acid + Coenzyme A unknown Adenosine monophosphate + hexadecanoyl-CoA + Pyrophosphatedetails
Gene Name:
UBE2G1
Uniprot ID:
P62253
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
QARS
Uniprot ID:
P47897
Reactions
Adenosine triphosphate + L-Glutamine + tRNA(Gln) unknown Adenosine monophosphate + Pyrophosphate + L-glutaminyl-tRNA(Gln)details
Adenosine triphosphate + L-Glutamine + tRNA(Gln) unknown Adenosine monophosphate + Pyrophosphate + Glutaminyl-tRNAdetails
Gene Name:
TARS
Uniprot ID:
P26639
Reactions
Adenosine triphosphate + L-Threonine + tRNA(Thr) unknown Adenosine monophosphate + Pyrophosphate + L-threonyl-tRNA(Thr)details
Adenosine triphosphate + L-Threonine + tRNA(Thr) unknown Adenosine monophosphate + Pyrophosphate + L-Threonyl-tRNA(Thr)details
Gene Name:
ASNS
Uniprot ID:
P08243
Reactions
Adenosine triphosphate + L-Aspartic acid + L-Glutamine + Water unknown Adenosine monophosphate + Pyrophosphate + L-Asparagine + L-Glutamic aciddetails
Gene Name:
UBE2E2
Uniprot ID:
Q96LR5
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
UBE2D2
Uniprot ID:
P62837
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
LIG4
Uniprot ID:
P49917
Reactions
Adenosine triphosphate + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) unknown Adenosine monophosphate + Pyrophosphate + (deoxyribonucleotide)(n+m)details
Gene Name:
RARS
Uniprot ID:
P54136
Reactions
Adenosine triphosphate + L-Arginine + tRNA(Arg) unknown Adenosine monophosphate + Pyrophosphate + L-arginyl-tRNA(Arg)details
Adenosine triphosphate + L-Arginine + tRNA(Arg) unknown Adenosine monophosphate + Pyrophosphate + L-Arginyl-tRNA(Arg)details
Gene Name:
GMPS
Uniprot ID:
P49915
Reactions
Adenosine triphosphate + Xanthylic acid + L-Glutamine + Water unknown Adenosine monophosphate + Pyrophosphate + Guanosine monophosphate + L-Glutamic aciddetails
Adenosine triphosphate + Xanthylic acid + Ammonia unknown Adenosine monophosphate + Pyrophosphate + Guanosine monophosphatedetails
6-Thioxanthine 5'-monophosphate + Adenosine triphosphate + L-Glutamine + Water unknown 6-Thioguanosine monophosphate + Adenosine monophosphate + Pyrophosphate + L-Glutamic aciddetails
Gene Name:
UBE2E3
Uniprot ID:
Q969T4
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
UBE2B
Uniprot ID:
P63146
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
LARS2
Uniprot ID:
Q15031
Reactions
Adenosine triphosphate + L-Leucine + tRNA(Leu) unknown Adenosine monophosphate + Pyrophosphate + L-leucyl-tRNA(Leu)details
Adenosine triphosphate + L-Leucine + tRNA(Leu) unknown Adenosine monophosphate + Pyrophosphate + L-Leucyl-tRNAdetails
Gene Name:
UBE2J2
Uniprot ID:
Q8N2K1
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
UBE2L3
Uniprot ID:
P68036
Reactions
Adenosine triphosphate + ubiquitin + protein lysine unknown Adenosine monophosphate + Pyrophosphate + protein N-ubiquityllysinedetails
Gene Name:
RTCA
Uniprot ID:
O00442
Reactions
Adenosine triphosphate + RNA 3'-terminal-phosphate unknown Adenosine monophosphate + Pyrophosphate + RNA terminal-2',3'-cyclic-phosphatedetails
Gene Name:
YARS
Uniprot ID:
P54577
Reactions
Adenosine triphosphate + L-Tyrosine + tRNA(Tyr) unknown Adenosine monophosphate + Pyrophosphate + L-tyrosyl-tRNA(Tyr)details
Adenosine triphosphate + L-Tyrosine + tRNA(Tyr) unknown Adenosine monophosphate + Pyrophosphate + L-Tyrosyl-tRNA(Tyr)details
Gene Name:
LIG3
Uniprot ID:
P49916
Reactions
Adenosine triphosphate + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) unknown Adenosine monophosphate + Pyrophosphate + (deoxyribonucleotide)(n+m)details

Only showing the first 50 proteins. There are 351 proteins in total.