Showing metabocard for Pyruvaldehyde (HMDB0001167)

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Gene Name:

AKR1B1

Uniprot ID:

P15121

Molecular weight:

35853.125

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.

Gene Name:

MAOB

Uniprot ID:

P27338

Molecular weight:

58762.475

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Gene Name:

MAOA

Uniprot ID:

P21397

Molecular weight:

59681.27

Reactions

General function:

Lipid transport and metabolism

Specific function:

Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.

Gene Name:

CEL

Uniprot ID:

P19835

Molecular weight:

79666.385

General function:

Involved in copper ion binding

Specific function:

Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.

Gene Name:

ABP1

Uniprot ID:

P19801

Molecular weight:

85377.1

General function:

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Specific function:

Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.

Gene Name:

GRHPR

Uniprot ID:

Q9UBQ7

Molecular weight:

35667.875

Reactions

General function:

Involved in lactoylglutathione lyase activity

Specific function:

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B.

Gene Name:

GLO1

Uniprot ID:

Q04760

Molecular weight:

20777.515

Reactions

General function:

Involved in copper ion binding

Specific function:

Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.

Gene Name:

AOC3

Uniprot ID:

Q16853

Molecular weight:

84621.27

Reactions

General function:

Involved in copper ion binding

Specific function:

Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.

Gene Name:

AOC2

Uniprot ID:

O75106

Molecular weight:

80515.11

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Does not exhibit retinol dehydrogenase (RDH) activity in vitro

Gene Name:

RDH13

Uniprot ID:

Q8NBN7

Molecular weight:

35931.8

General function:

Not Available

Specific function:

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Gene Name:

AKR1B10

Uniprot ID:

O60218

Molecular weight:

Not Available

Reactions