Human Metabolome Database Version 3.5

Showing metabocard for FAD (HMDB01248)

Record Information
Version 3.5
Creation Date 2005-11-16 08:48:42 -0700
Update Date 2013-02-08 17:10:10 -0700
HMDB ID HMDB01248
Secondary Accession Numbers None
Metabolite Identification
Common Name FAD
Description FAD is a condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972).
Structure Thumb
Download: MOL | SDF | PDB | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. 1H-Purin-6-amine flavin dinucleotide
  2. 1H-Purin-6-amine flavine dinucleotide
  3. Adenine-flavin dinucleotide
  4. Adenine-flavine dinucleotide
  5. Adenine-riboflavin dinuceotide
  6. Adenine-riboflavin dinucleotide
  7. Adenine-riboflavine dinucleotide
  8. FAD
  9. Flamitajin B
  10. Flanin F
  11. Flavin adenine dinucleotide
  12. Flavin adenine dinucleotide oxidized
  13. Flavin-adenine dinucleotide
  14. Flavine adenosine diphosphate
  15. Flavine-adenine dinucleotide
  16. Flavitan
  17. Flaziren
  18. Isoalloxazine-adenine dinucleotide
  19. Riboflavin 5'-adenosine diphosphate
  20. Riboflavin-adenine dinucleotide
  21. Riboflavine-adenine dinucleotide
Chemical Formula C27H33N9O15P2
Average Molecular Weight 785.5497
Monoisotopic Molecular Weight 785.157134455
IUPAC Name {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid
Traditional IUPAC Name [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy({[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-3H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy(hydroxy)phosphoryl}oxy)phosphinic acid
CAS Registry Number 146-14-5
SMILES CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
InChI Identifier InChI=1S/C27H33N9O15P2/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43)/t14-,15+,16+,19-,20+,21+,26+/m0/s1
InChI Key VWWQXMAJTJZDQX-UYBVJOGSSA-N
Chemical Taxonomy
Kingdom Organic Compounds
Super Class Nucleosides, Nucleotides, and Analogues
Class Flavin Nucleotides
Sub Class N/A
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
  • flavin adenine dinucleotide(ChEBI)
Substituents
  • 1,2 Diol
  • 1 Phosphoribosyl Imidazole
  • Aminopyrimidine
  • Disaccharide Phosphate
  • Flavin
  • Glycosyl Compound
  • Imidazole
  • Imidazopyrimidine
  • Isoalloxazine
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Organic Pyrophosphate
  • Oxolane
  • Pentose Disaccharide
  • Phosphoric Acid Ester
  • Pteridine
  • Purine
  • Purine Ribonucleoside Diphosphate
  • Pyrazine
  • Pyrimidine
  • Pyrimidone
  • Quinoxaline
  • Saccharide
  • Secondary Alcohol
  • Toluene
Direct Parent Flavin Nucleotides
Ontology
Status Detected and Quantified
Origin
  • Endogenous
Biofunction
  • Enzyme cofactor
Application Not Available
Cellular locations
  • Cytoplasm
  • Mitochondria
  • Endoplasmic reticulum
  • Peroxisome
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point Not Available Not Available
Boiling Point Not Available Not Available
Water Solubility 5 mg/mL Not Available
LogP Not Available Not Available
Predicted Properties
Property Value Source
Water Solubility 4.25 g/L ALOGPS
LogP -0.78 ALOGPS
LogP -5.3 ChemAxon
LogS -2.27 ALOGPS
pKa (strongest acidic) 1.86 ChemAxon
pKa (strongest basic) 4.99 ChemAxon
Hydrogen Acceptor Count 19 ChemAxon
Hydrogen Donor Count 9 ChemAxon
Polar Surface Area 356.42 A2 ChemAxon
Rotatable Bond Count 13 ChemAxon
Refractivity 177.43 ChemAxon
Polarizability 70.11 ChemAxon
Formal Charge 0 ChemAxon
Physiological Charge -3 ChemAxon
Spectra
1H NMR Spectrum
MS/MS Spectrum Quattro_QQQ 10
MS/MS Spectrum Quattro_QQQ 25
MS/MS Spectrum Quattro_QQQ 40
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
MS/MS Spectrum LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic)
[1H,1H] 2D NMR Spectrum
[1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm
  • Mitochondria
  • Endoplasmic reticulum
  • Peroxisome
Biofluid Locations
  • Blood
Tissue Location
  • Muscle
  • Erythrocyte
  • Liver
Pathways
Name SMPDB Link KEGG Link
Citric Acid Cycle SMP00057 map00020 Link_out
Glycerol Phosphate Shuttle SMP00124 Not Available
Riboflavin Metabolism SMP00070 map00740 Link_out
Normal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified
0.061 (0.044-0.078) uM Adult (>18 years old) Female Normal
Blood Detected and Quantified
0.078 +/- 0.054 uM Adolescent (13-18 years old) Female Normal
Blood Detected and Quantified
0.075 (0.056-0.097) uM Adult (>18 years old) Both Normal
Abnormal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified 0.031 +/- 0.01 uM Children (1-13 year old) Both Severely malnourished children
Blood Detected and Quantified 0.048 +/- 0.023 uM Adolescent (13-18 years old) Female Anorexia nervosa
Associated Disorders and Diseases
Disease References
Anorexia nervosa
  • Capo-chichi CD, Gueant JL, Lefebvre E, Bennani N, Lorentz E, Vidailhet C, Vidailhet M: Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa. Am J Clin Nutr. 1999 Apr;69(4):672-8. Pubmed: 10197568 Link_out
      Associated OMIM IDs
      DrugBank ID Not Available
      DrugBank Metabolite ID Not Available
      Phenol Explorer Compound ID Not Available
      Phenol Explorer Metabolite ID Not Available
      FoodDB ID FDB022511
      KNApSAcK ID Not Available
      Chemspider ID 559059 Link_out
      KEGG Compound ID C00016 Link_out
      BioCyc ID FAD Link_out
      BiGG ID 33521 Link_out
      Wikipedia Link FAD Link_out
      NuGOwiki Link HMDB01248 Link_out
      Metagene Link HMDB01248 Link_out
      METLIN ID 6106 Link_out
      PubChem Compound 643975 Link_out
      PDB ID FAD Link_out
      ChEBI ID 16238 Link_out
      References
      Synthesis Reference Not Available
      Material Safety Data Sheet (MSDS) Download (PDF)
      General References
      1. Flatz G, Simmersbach F: Flavin adenine dinucleotide concentration in erythrocytes with normal and deficient glucose-6-phosphate dehydrogenase. Klin Wochenschr. 1970 Sep 1;48(17):1071-2. Pubmed: 5523465 Link_out
      2. Zempleni J: Determination of riboflavin and flavocoenzymes in human blood plasma by high-performance liquid chromatography. Ann Nutr Metab. 1995;39(4):224-6. Pubmed: 8546438 Link_out
      3. Becker K, Wilkinson AR: Flavin adenine dinucleotide levels in erythrocytes of very low birthweight infants under vitamin supplementation. Biol Neonate. 1993;63(2):80-5. Pubmed: 8448258 Link_out
      4. Lisowsky T, Lee JE, Polimeno L, Francavilla A, Hofhaus G: Mammalian augmenter of liver regeneration protein is a sulfhydryl oxidase. Dig Liver Dis. 2001 Mar;33(2):173-80. Pubmed: 11346147 Link_out
      5. Cimino JA, Jhangiani S, Schwartz E, Cooperman JM: Riboflavin metabolism in the hypothyroid human adult. Proc Soc Exp Biol Med. 1987 Feb;184(2):151-3. Pubmed: 3809170 Link_out
      6. Kodentsova VM, Vrzhesinskaia OA, Alekseeva IA, Spirichev VB: [Comparison of biochemical criteria for supplying the human body with riboflavin] Vopr Med Khim. 1991 Sep-Oct;37(5):76-9. Pubmed: 1759408 Link_out
      7. Lopez-Anaya A, Mayersohn M: Quantification of riboflavin, riboflavin 5'-phosphate and flavin adenine dinucleotide in plasma and urine by high-performance liquid chromatography. J Chromatogr. 1987 Dec 25;423:105-13. Pubmed: 3443641 Link_out
      8. Van Binsbergen CJ, Odink J, Van den Berg H, Koppeschaar H, Coelingh Bennink HJ: Nutritional status in anorexia nervosa: clinical chemistry, vitamins, iron and zinc. Eur J Clin Nutr. 1988 Nov;42(11):929-37. Pubmed: 3074921 Link_out
      9. Mohrenweiser HW, Novotny JE: ACP1GUA-1--a low-activity variant of human erythrocyte acid phosphatase: association with increased glutathione reductase activity. Am J Hum Genet. 1982 May;34(3):425-33. Pubmed: 7081221 Link_out
      10. Gianazza E, Vergani L, Wait R, Brizio C, Brambilla D, Begum S, Giancaspero TA, Conserva F, Eberini I, Bufano D, Angelini C, Pegoraro E, Tramontano A, Barile M: Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin-responsive, multiple acyl-CoA dehydrogenase deficiency patient. Electrophoresis. 2006 Mar;27(5-6):1182-98. Pubmed: 16470778 Link_out
      11. Cimino JA, Noto RA, Fusco CL, Cooperman JM: Riboflavin metabolism in the hypothyroid newborn. Am J Clin Nutr. 1988 Mar;47(3):481-3. Pubmed: 3348160 Link_out

      Enzymes

      Show all enzymes and transporters Important Only showing the first 50 enzymes. There are 166 enzymes in total.

      Name: Dihydrolipoyl dehydrogenase, mitochondrial
      Reactions: Not Available
      Gene Name: DLD
      Uniprot ID: P09622 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Long-chain specific acyl-CoA dehydrogenase, mitochondrial
      Reactions:
      hexadecanoyl-CoA + FAD unknown (2E)-Hexadecenoyl-CoA + FADH details
      Octanoyl-CoA + FAD unknown (2E)-Octenoyl-CoA + FADH details
      Lauroyl-CoA + FAD unknown (2E)-Dodecenoyl-CoA + FADH details
      Tetradecanoyl-CoA + FAD unknown (2E)-Tetradecenoyl-CoA + FADH details
      Hexanoyl-CoA + FAD unknown trans-2-Hexenoyl-CoA + FADH details
      Decanoyl-CoA (n-C10:0CoA) + FAD unknown (2E)-Decenoyl-CoA + FADH details
      Gene Name: ACADL
      Uniprot ID: P28330 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Short-chain specific acyl-CoA dehydrogenase, mitochondrial
      Reactions:
      Butyryl-CoA + FAD unknown FADH + (E)-but-2-enoyl-CoA details
      Hexanoyl-CoA + FAD unknown trans-2-Hexenoyl-CoA + FADH details
      Gene Name: ACADS
      Uniprot ID: P16219 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
      Reactions:
      Propionyl-CoA + FAD unknown FADH + Acrylyl-CoA details
      Butyryl-CoA + FAD unknown FADH + (E)-but-2-enoyl-CoA details
      hexadecanoyl-CoA + FAD unknown (2E)-Hexadecenoyl-CoA + FADH details
      Octanoyl-CoA + FAD unknown (2E)-Octenoyl-CoA + FADH details
      Lauroyl-CoA + FAD unknown (2E)-Dodecenoyl-CoA + FADH details
      Tetradecanoyl-CoA + FAD unknown (2E)-Tetradecenoyl-CoA + FADH details
      Isovaleryl-CoA + FAD unknown 3-Methylcrotonyl-CoA + FADH details
      Hexanoyl-CoA + FAD unknown trans-2-Hexenoyl-CoA + FADH details
      Decanoyl-CoA (n-C10:0CoA) + FAD unknown (2E)-Decenoyl-CoA + FADH details
      Gene Name: ACADM
      Uniprot ID: P11310 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH-ubiquinone oxidoreductase chain 1
      Reactions: Not Available
      Gene Name: MT-ND1
      Uniprot ID: P03886 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
      Reactions: Not Available
      Gene Name: NDUFB1
      Uniprot ID: O75438 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
      Reactions:
      FAD + Water unknown Adenosine monophosphate + Flavin Mononucleotide details
      Gene Name: ENPP1
      Uniprot ID: P22413 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFS2
      Uniprot ID: O75306 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
      Reactions: Not Available
      Gene Name: SDHC
      Uniprot ID: Q99643 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Peroxisomal sarcosine oxidase
      Reactions: Not Available
      Gene Name: PIPOX
      Uniprot ID: Q9P0Z9 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
      Reactions: Not Available
      Gene Name: PAOX
      Uniprot ID: Q6QHF9 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
      Reactions: Not Available
      Gene Name: NDUFA12
      Uniprot ID: Q9UI09 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH-cytochrome b5 reductase 3
      Reactions: Not Available
      Gene Name: CYB5R3
      Uniprot ID: P00387 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Aldehyde oxidase
      Reactions: Not Available
      Gene Name: AOX1
      Uniprot ID: Q06278 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
      Reactions: Not Available
      Gene Name: NDUFA1
      Uniprot ID: O15239 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2
      Reactions: Not Available
      Gene Name: NDUFA4L2
      Uniprot ID: Q9NRX3 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
      Reactions: Not Available
      Gene Name: NDUFA3
      Uniprot ID: O95167 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
      Reactions: Not Available
      Gene Name: NDUFA8
      Uniprot ID: P51970 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
      Reactions: Not Available
      Gene Name: NDUFA4
      Uniprot ID: O00483 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH-ubiquinone oxidoreductase chain 4L
      Reactions: Not Available
      Gene Name: MT-ND4L
      Uniprot ID: P03901 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
      Reactions: Not Available
      Gene Name: NDUFA11
      Uniprot ID: Q86Y39 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Thioredoxin reductase 1, cytoplasmic
      Reactions: Not Available
      Gene Name: TXNRD1
      Uniprot ID: Q16881 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Lathosterol oxidase
      Reactions: Not Available
      Gene Name: SC5DL
      Uniprot ID: O75845 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFS4
      Uniprot ID: O43181 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Ribosyldihydronicotinamide dehydrogenase [quinone]
      Reactions: Not Available
      Gene Name: NQO2
      Uniprot ID: P16083 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFS3
      Uniprot ID: O75489 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
      Reactions: Not Available
      Gene Name: NDUFS5
      Uniprot ID: O43920 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFV2
      Uniprot ID: P19404 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Dimethylaniline monooxygenase [N-oxide-forming] 5
      Reactions: Not Available
      Gene Name: FMO5
      Uniprot ID: P49326 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFA10
      Uniprot ID: O95299 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
      Reactions: Not Available
      Gene Name: NDUFA6
      Uniprot ID: P56556 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Peroxisomal acyl-coenzyme A oxidase 1
      Reactions:
      Butyryl-CoA + FAD unknown FADH + (E)-but-2-enoyl-CoA details
      hexadecanoyl-CoA + FAD unknown (2E)-Hexadecenoyl-CoA + FADH details
      Octanoyl-CoA + FAD unknown (2E)-Octenoyl-CoA + FADH details
      Lauroyl-CoA + FAD unknown (2E)-Dodecenoyl-CoA + FADH details
      Tetradecanoyl-CoA + FAD unknown (2E)-Tetradecenoyl-CoA + FADH details
      Hexanoyl-CoA + FAD unknown trans-2-Hexenoyl-CoA + FADH details
      Decanoyl-CoA (n-C10:0CoA) + FAD unknown (2E)-Decenoyl-CoA + FADH details
      OPC8-CoA + FAD unknown trans-2-Enoyl-OPC8-CoA + FADH details
      OPC6-CoA + FAD unknown trans-2-Enoyl-OPC6-CoA + FADH details
      OPC4-CoA + FAD unknown trans-2-Enoyl-OPC4-CoA + FADH details
      Tetracosahexaenoyl CoA + FAD unknown Trans-2-all-cis-6,9,12,15,18,21-tetracosaheptaenoyl-CoA + FADH details
      Tetracosapentaenoyl coenzyme A, n-6 + FAD unknown (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexa-2,6,9,12,15,18-enoyl-CoA + FADH details
      Gene Name: ACOX1
      Uniprot ID: Q15067 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: D-aspartate oxidase
      Reactions: Not Available
      Gene Name: DDO
      Uniprot ID: Q99489 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
      Reactions: Not Available
      Gene Name: NDUFB4
      Uniprot ID: O95168 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
      Reactions: Not Available
      Gene Name: SDHA
      Uniprot ID: P31040 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Heme oxygenase 2
      Reactions:
      Hemoglobin + FADH + Oxygen unknown Globin + Biliverdin + Carbon monoxide + Fe3+ + FAD + Water details
      Gene Name: HMOX2
      Uniprot ID: P30519 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFS8
      Uniprot ID: O00217 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Squalene monooxygenase
      Reactions: Not Available
      Gene Name: SQLE
      Uniprot ID: Q14534 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH-ubiquinone oxidoreductase chain 2
      Reactions: Not Available
      Gene Name: MT-ND2
      Uniprot ID: P03891 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Dimethylaniline monooxygenase [N-oxide-forming] 2
      Reactions: Not Available
      Gene Name: FMO2
      Uniprot ID: Q99518 Link_out
      Protein Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
      Reactions: Not Available
      Gene Name: NDUFA7
      Uniprot ID: O95182 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Thioredoxin reductase 2, mitochondrial
      Reactions: Not Available
      Gene Name: TXNRD2
      Uniprot ID: Q9NNW7 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
      Reactions: Not Available
      Gene Name: NDUFA2
      Uniprot ID: O43678 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Methionine synthase
      Reactions: Not Available
      Gene Name: MTR
      Uniprot ID: Q99707 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Amine oxidase [flavin-containing] B
      Reactions: Not Available
      Gene Name: MAOB
      Uniprot ID: P27338 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFS1
      Uniprot ID: P28331 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
      Reactions: Not Available
      Gene Name: NDUFB5
      Uniprot ID: O43674 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Peroxisomal acyl-coenzyme A oxidase 2
      Reactions: Not Available
      Gene Name: ACOX2
      Uniprot ID: Q99424 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Dimethylaniline monooxygenase [N-oxide-forming] 4
      Reactions: Not Available
      Gene Name: FMO4
      Uniprot ID: P31512 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA
      Name: Isovaleryl-CoA dehydrogenase, mitochondrial
      Reactions:
      Isovaleryl-CoA + FAD unknown 3-Methylcrotonyl-CoA + FADH details
      Gene Name: IVD
      Uniprot ID: P26440 Link_out
      Protein Sequence: FASTA
      Gene Sequence: FASTA