HMDB0015026 | Granisetron | 109889-09-0 | | C18H24N4O | 312.4094 312.19501141 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0001830 | Progesterone | 57-83-0 | | C21H30O2 | 314.4617 314.224580204 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014640 | Oxycodone | 76-42-6 | | C18H21NO4 | 315.3636 315.147058165 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0015634 | Saxagliptin | 361442-04-8 | | C18H25N3O2 | 315.41 315.194677059 | - Upreti VV, Boulton DW, Li L, Ching A, Su H, Lacreta FP, Patel CG: Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects. Br J Clin Pharmacol. 2011 Jul;72(1):92-102. doi: 10.1111/j.1365-2125.2011.03937.x. [PubMed:21651615 ]
- Patel CG, Kornhauser D, Vachharajani N, Komoroski B, Brenner E, Handschuh del Corral M, Li L, Boulton DW: Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects. Diabetes Obes Metab. 2011 Jul;13(7):604-14. doi: 10.1111/j.1463-1326.2011.01381.x. [PubMed:21332626 ]
- Scheen AJ: Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions. Clin Pharmacokinet. 2010 Sep;49(9):573-88. doi: 10.2165/11532980-000000000-00000. [PubMed:20690781 ]
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HMDB0014869 | Nateglinide | 105816-04-4 | | C19H27NO3 | 317.4226 317.199093735 | Not Available |
HMDB0014322 | Fluvoxamine | 54739-18-3 | | C15H21F3N2O2 | 318.3346 318.155512541 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0015192 | Norfloxacin | 70458-96-7 | | C16H18FN3O3 | 319.3308 319.133219662 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014746 | Chloroquine | 54-05-7 | | C18H26ClN3 | 319.872 319.181525554 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0011136 | 19(S)-HETE | 79551-85-2 | | C20H32O3 | 320.4663 320.23514489 | Not Available |
HMDB0002190 | 5,6-Epoxy-8,11,14-eicosatrienoic acid | 81246-84-6 | | C20H32O3 | 320.4663 320.23514489 | Not Available |
HMDB0002232 | 8,9-Epoxyeicosatrienoic acid | 81246-85-7 | | C20H32O3 | 320.4663 320.23514489 | Not Available |
HMDB0004264 | 14,15-Epoxy-5,8,11-eicosatrienoic acid | 81276-03-1 | | C20H32O3 | 320.4663 320.23514489 | Not Available |
HMDB0004680 | 16(R)-HETE | | | C20H32O3 | 320.4663 320.23514489 | Not Available |
HMDB0004673 | 11,12-Epoxyeicosatrienoic acid | 123931-40-8 | | C20H32O3 | 320.473 320.23514489 | Not Available |
HMDB0005011 | Clopidogrel | 113665-84-2 | | C16H16ClNO2S | 321.822 321.059027158 | Not Available |
HMDB0014589 | Chloramphenicol | 56-75-7 | | C11H12Cl2N2O5 | 323.129 322.012326918 | Not Available |
HMDB0005038 | Citalopram | 59729-33-8 | | C20H21FN2O | 324.3919 324.163791509 | Not Available |
HMDB0014611 | Quinine | 130-95-0 | | C20H24N2O2 | 324.4168 324.183778022 | Not Available |
HMDB0013943 | Alpha-hydroxyalprazolam | 37115-43-8 | | C17H13ClN4O | 324.764 324.077788765 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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HMDB0014821 | Midazolam | 59467-70-8 | | C18H13ClFN3 | 325.767 325.078203343 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Rendic S: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448. [PubMed:11996015 ]
- Patki KC, Von Moltke LL, Greenblatt DJ: In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5. Drug Metab Dispos. 2003 Jul;31(7):938-44. [PubMed:12814972 ]
- Wandel C, Bocker R, Bohrer H, Browne A, Rugheimer E, Martin E: Midazolam is metabolized by at least three different cytochrome P450 enzymes. Br J Anaesth. 1994 Nov;73(5):658-61. [PubMed:7826796 ]
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HMDB0014677 | Ciprofloxacin | 85721-33-1 | | C17H18FN3O3 | 331.3415 331.133219662 | Not Available |
HMDB0004244 | 15(S)-HPETE | 70981-96-3 | | C20H32O4 | 336.4657 336.230059512 | Not Available |
HMDB0004693 | 11H-14,15-EETA | 219535-29-2 | | C20H32O4 | 336.4657 336.230059512 | Not Available |
HMDB0005050 | 15H-11,12-EETA | 877878-78-9 | | C20H32O4 | 336.4657 336.230059512 | Not Available |
HMDB0014951 | Fentanyl | 437-38-7 | | C22H28N2O | 336.4705 336.220163528 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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