Record Information
Version3.6
Creation Date2005-11-16 15:48:42 UTC
Update Date2013-05-29 19:27:29 UTC
HMDB IDHMDB00538
Secondary Accession NumbersNone
Metabolite Identification
Common NameAdenosine triphosphate
DescriptionAdenosine triphosphate (ATP) is a nucleotide consisting of a purine base (adenine) attached to the first carbon atom of ribose (a pentose sugar). Three phosphate groups are esterified at the fifth carbon atom of the ribose. ATP is incorporated into nucleic acids by polymerases in the processes of DNA replication and transcription. ATP contributes to cellular energy charge and participates in overall energy balance, maintaining cellular homeostasis. ATP can act as an extracellular signaling molecule via interactions with specific purinergic receptors to mediate a wide variety of processes as diverse as neurotransmission, inflammation, apoptosis, and bone remodelling. Extracellular ATP and its metabolite adenosine have also been shown to exert a variety of effects on nearly every cell type in human skin, and ATP seems to play a direct role in triggering skin inflammatory, regenerative, and fibrotic responses to mechanical injury, an indirect role in melanocyte proliferation and apoptosis, and a complex role in Langerhans cell-directed adaptive immunity. During exercise, intracellular homeostasis depends on the matching of adenosine triphosphate (ATP) supply and ATP demand. Metabolites play a useful role in communicating the extent of ATP demand to the metabolic supply pathways. Effects as different as proliferation or differentiation, chemotaxis, release of cytokines or lysosomal constituents, and generation of reactive oxygen or nitrogen species are elicited upon stimulation of blood cells with extracellular ATP. The increased concentration of adenosine triphosphate (ATP) in erythrocytes from patients with chronic renal failure (CRF) has been observed in many studies but the mechanism leading to these abnormalities still is controversial. (PMID: 15490415 , 15129319 , 14707763 , 14696970 , 11157473 ).
Structure
Thumb
Synonyms
  1. 5'-(Tetrahydrogen triphosphate) Adenosine
  2. 5'-ATP
  3. Adenosine 5'-triphosphate
  4. Adenosine 5'-triphosphorate
  5. Adenosine 5'-triphosphoric acid
  6. Adenosine triphosphate
  7. Adenylpyrophosphorate
  8. Adenylpyrophosphoric acid
  9. Adephos
  10. Adetol
  11. Adynol
  12. Atipi
  13. ATP
  14. Atriphos
  15. Cardenosine
  16. Fosfobion
  17. Glucobasin
  18. Myotriphos
  19. Phosphobion
  20. Striadyne
  21. Triadenyl
  22. Triphosphaden
  23. Triphosphoric acid adenosine ester
Chemical FormulaC10H16N5O13P3
Average Molecular Weight507.181
Monoisotopic Molecular Weight506.995745159
IUPAC Name({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
Traditional IUPAC Name({[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid
CAS Registry Number56-65-5
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Identifier
InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI KeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassNucleosides, Nucleotides, and Analogues
ClassPurine Nucleotides
Sub ClassPurine Ribonucleotides
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
  • Coenzymes(KEGG)
  • Ribonucleotides(KEGG)
  • adenosine 5'-phosphate(ChEBI)
  • purine ribonucleoside 5'-triphosphate(ChEBI)
Substituents
  • 1,2 Diol
  • 1 Phosphoribosyl Imidazole
  • Aminopyrimidine
  • Glycosyl Compound
  • Imidazole
  • Imidazopyrimidine
  • Monosaccharide Phosphate
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Organic Pyrophosphate
  • Oxolane
  • Pentose Monosaccharide
  • Phosphoric Acid Ester
  • Purine
  • Pyrimidine
  • Saccharide
  • Secondary Alcohol
Direct ParentPurine Ribonucleoside Triphosphates
Ontology
StatusDetected and Quantified
Origin
  • Endogenous
Biofunction
  • Component of Aminosugars metabolism
  • Component of Fructose and mannose metabolism
  • Component of Galactose metabolism
  • Component of Starch and sucrose metabolism
  • Component of Streptomycin biosynthesis
ApplicationNot Available
Cellular locations
  • Cytoplasm
  • Extracellular
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Peroxisome
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water Solubility1000.0 mg/mL; 862 mg/mL (magnesium salt)MERCK INDEX (1996); Human Metabolome Project (salt)
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
water solubility4.49 g/LALOGPS
logP-0.84ALOGPS
logP-6.2ChemAxon
logS-2ALOGPS
pKa (strongest acidic)0.9ChemAxon
pKa (strongest basic)5ChemAxon
physiological charge-3ChemAxon
hydrogen acceptor count14ChemAxon
hydrogen donor count7ChemAxon
polar surface area279.13ChemAxon
rotatable bond count8ChemAxon
refractivity95.81ChemAxon
polarizability38.76ChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Peroxisome
Biofluid Locations
  • Blood
  • Cellular Cytoplasm
  • Cerebrospinal Fluid (CSF)
Tissue Location
  • Adipose Tissue
  • Bladder
  • Fibroblasts
  • Intestine
  • Kidney
  • Muscle
  • Myelin
  • Nerve Cells
  • Neuron
  • Pancreas
  • Platelet
  • Skeletal Muscle
Pathways
NameSMPDB LinkKEGG Link
Amino Sugar MetabolismSMP00045map00520
Ammonia RecyclingSMP00009map00910
Citric Acid CycleSMP00057map00020
DNA Replication ForkSMP00477Not Available
Ethanol DegradationSMP00449Not Available
Folate MetabolismSMP00053map00670
GluconeogenesisSMP00128map00010
Glycerolipid MetabolismSMP00039map00561
Glycine and Serine MetabolismSMP00004map00260
GlycolysisSMP00040map00010
Histidine MetabolismSMP00044map00340
Inositol Phosphate MetabolismSMP00462map00562
Lactose DegradationSMP00457Not Available
Lactose SynthesisSMP00444Not Available
Methionine MetabolismSMP00033map00270
Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty AcidsSMP00482Not Available
Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty AcidsSMP00481Not Available
Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty AcidsSMP00480Not Available
Mitochondrial Electron Transport ChainSMP00355map00190
Phosphatidylinositol Phosphate MetabolismSMP00463map00562
Phytanic Acid Peroxisomal OxidationSMP00450Not Available
Purine MetabolismSMP00050map00230
Spermidine and Spermine BiosynthesisSMP00445Not Available
Threonine and 2-Oxobutanoate DegradationSMP00452Not Available
Transcription/TranslationSMP00019Not Available
Transfer of Acetyl Groups into MitochondriaSMP00466Not Available
Trehalose DegradationSMP00467Not Available
Urea CycleSMP00059map00330
Normal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified1077.0 +/- 210.0 uMNewborn (0-30 days old)BothNormal
  • Geigy Scient...
BloodDetected and Quantified1552.0 +/- 161.0 uMAdult (>18 years old)MaleNormal
  • Geigy Scient...
BloodDetected and Quantified1390.0 +/- 170.0 uMAdult (>18 years old)BothNormal
  • Geigy Scient...
BloodDetected and Quantified3152.0 +/- 1698.0 uMAdult (>18 years old)BothNormal
Cellular CytoplasmDetected and Quantified1540 (1290-1790) uMAdult (>18 years old)BothNormal
Cerebrospinal Fluid (CSF)Detected and Quantified1.85 +/- 0.03 uMAdult (>18 years old)BothNormal
Abnormal Concentrations
BiofluidStatusValueAgeSexConditionReference
Cerebrospinal Fluid (CSF)Detected and Quantified0.23 +/- 0.19 uMAdult (>18 years old)BothRachialgia
Cerebrospinal Fluid (CSF)Detected and Quantified0.80 +/- 0.63 uMAdult (>18 years old)BothSubarachnoid hemorrhage
Cerebrospinal Fluid (CSF)Detected and Quantified1.08 +/- 0.77 uMAdult (>18 years old)BothEpilepsy
Cerebrospinal Fluid (CSF)Detected and Quantified0.26 +/- 0.11 uMAdult (>18 years old)BothCommentStroke
Cerebrospinal Fluid (CSF)Detected and Quantified1.09 +/- 0.76 uMAdult (>18 years old)BothNeuroinfection
Associated Disorders and Diseases
Disease References
Subarachnoid hemorrhage
  • Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Epilepsy
  • Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Neuroinfection
  • Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Rachialgia
  • Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Stroke
  • Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Associated OMIM IDs
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB021813
KNApSAcK IDNot Available
Chemspider ID5742
KEGG Compound IDC00002
BioCyc IDATP
BiGG ID33477
Wikipedia LinkAdenosine triphosphate
NuGOwiki LinkHMDB00538
Metagene LinkHMDB00538
METLIN ID5523
PubChem Compound5957
PDB IDATP
ChEBI ID15422
References
Synthesis ReferenceClark, V. M.; Kirby, G. W.; Todd, Alexander. Phosphorylation. XV. Use of phosphoramidic esters in acylation-new preparation of adenosine 5'-pyrophosphate and adenosine 5'-triphosphate. Journal of the Chemical Society (1957), 1497-1501.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Nakayama Y, Kinoshita A, Tomita M: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005 May 9;2(1):18. Pubmed: 15882454
  2. Gottlieb C, Svanborg K, Eneroth P, Bygdeman M: Effect of prostaglandins on human sperm function in vitro and seminal adenosine triphosphate content. Fertil Steril. 1988 Feb;49(2):322-7. Pubmed: 3338588
  3. Mahmoud AM, Comhaire FH, Vermeulen L, Andreou E: Comparison of the resazurin test, adenosine triphosphate in semen, and various sperm parameters. Hum Reprod. 1994 Sep;9(9):1688-93. Pubmed: 7836519
  4. Kadmon M, Klunemann C, Bohme M, Ishikawa T, Gorgas K, Otto G, Herfarth C, Keppler D: Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. Gastroenterology. 1993 May;104(5):1507-14. Pubmed: 7683296
  5. Sun Y, MaLossi J, Jacobs SC, Chai TC: Effect of doxazosin on stretch-activated adenosine triphosphate release in bladder urothelial cells from patients with benign prostatic hyperplasia. Urology. 2002 Aug;60(2):351-6. Pubmed: 12137852
  6. Ryan LM, Rachow JW, McCarty BA, McCarty DJ: Adenosine triphosphate levels in human plasma. J Rheumatol. 1996 Feb;23(2):214-9. Pubmed: 8882021
  7. Yoshida M, Miyamae K, Iwashita H, Otani M, Inadome A: Management of detrusor dysfunction in the elderly: changes in acetylcholine and adenosine triphosphate release during aging. Urology. 2004 Mar;63(3 Suppl 1):17-23. Pubmed: 15013648
  8. Bar-Meir M, Elpeleg ON, Saada A: Effect of various agents on adenosine triphosphate synthesis in mitochondrial complex I deficiency. J Pediatr. 2001 Dec;139(6):868-70. Pubmed: 11743516
  9. Mannucci L, Pastore A, Rizzo C, Piemonte F, Rizzoni G, Emma F: Impaired activity of the gamma-glutamyl cycle in nephropathic cystinosis fibroblasts. Pediatr Res. 2006 Feb;59(2):332-5. Pubmed: 16439602
  10. Livingston JH, Brown JK, Harkness RA, McCreanor GM: Cerebrospinal fluid nucleotide metabolites following non-convulsive status epilepticus. Dev Med Child Neurol. 1989 Apr;31(2):168-73. Pubmed: 2737369
  11. Rutkowski B, Swierczynski J, Slominska E, Szolkiewicz M, Smolenski RT, Marlewski M, Butto B, Rutkowski P: Disturbances of purine nucleotide metabolism in uremia. Semin Nephrol. 2004 Sep;24(5):479-83. Pubmed: 15490415
  12. Holzer AM, Granstein RD: Role of extracellular adenosine triphosphate in human skin. J Cutan Med Surg. 2004 Mar-Apr;8(2):90-6. Epub 2004 May 3. Pubmed: 15129319
  13. Myburgh KH: Can any metabolites partially alleviate fatigue manifestations at the cross-bridge? Med Sci Sports Exerc. 2004 Jan;36(1):20-7. Pubmed: 14707763
  14. Gartland A, Buckley KA, Hipskind RA, Bowler WB, Gallagher JA: P2 receptors in bone--modulation of osteoclast formation and activity via P2X7 activation. Crit Rev Eukaryot Gene Expr. 2003;13(2-4):237-42. Pubmed: 14696970
  15. Di Virgilio F, Chiozzi P, Ferrari D, Falzoni S, Sanz JM, Morelli A, Torboli M, Bolognesi G, Baricordi OR: Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood. 2001 Feb 1;97(3):587-600. Pubmed: 11157473

Only showing the first 50 proteins. There are 1040 proteins in total.

Enzymes

Gene Name:
CMPK1
Uniprot ID:
P30085
Reactions
Adenosine triphosphate + (d)CMP unknown ADP + (d)CDPdetails
Adenosine triphosphate + Uridine 5'-monophosphate unknown ADP + Uridine 5'-diphosphatedetails
Adenosine triphosphate + Cytidine monophosphate unknown ADP + CDPdetails
Adenosine triphosphate + dCMP unknown ADP + dCDPdetails
Gene Name:
DCK
Uniprot ID:
P27707
Reactions
Adenosine triphosphate + Adenosine unknown ADP + Adenosine monophosphatedetails
Adenosine triphosphate + Deoxycytidine unknown ADP + dCMPdetails
Gene Name:
ACLY
Uniprot ID:
P53396
Reactions
ADP + Phosphoric acid + Acetyl-CoA + Oxalacetic acid unknown Adenosine triphosphate + Citric acid + Coenzyme Adetails
Adenosine triphosphate + Citric acid + Coenzyme A unknown ADP + Phosphoric acid + Acetyl-CoA + Oxalacetic aciddetails
Gene Name:
ACACB
Uniprot ID:
O00763
Reactions
Adenosine triphosphate + Acetyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + Malonyl-CoAdetails
Adenosine triphosphate + biotin-[carboxyl-carrier-protein] + CO(2) unknown ADP + Phosphoric acid + carboxy-biotin-[carboxyl-carrier-protein]details
Adenosine triphosphate + Holo-[carboxylase] + Carbonic acid unknown ADP + Phosphoric acid + Carboxybiotin-carboxyl-carrier proteindetails
Gene Name:
PC
Uniprot ID:
P11498
Reactions
Adenosine triphosphate + Pyruvic acid + Carbonic acid unknown ADP + Phosphoric acid + Oxalacetic aciddetails
Gene Name:
ACSS2
Uniprot ID:
Q9NR19
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Adenosine triphosphate + Acetic acid unknown Pyrophosphate + Acetyl adenylatedetails
Adenosine triphosphate + Propionic acid unknown Pyrophosphate + Propinol adenylatedetails
Gene Name:
ACSS1
Uniprot ID:
Q9NUB1
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Adenosine triphosphate + Acetic acid unknown Pyrophosphate + Acetyl adenylatedetails
Adenosine triphosphate + Propionic acid unknown Pyrophosphate + Propinol adenylatedetails
Gene Name:
ACACA
Uniprot ID:
Q13085
Reactions
Adenosine triphosphate + Acetyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + Malonyl-CoAdetails
Adenosine triphosphate + biotin-[carboxyl-carrier-protein] + CO(2) unknown ADP + Phosphoric acid + carboxy-biotin-[carboxyl-carrier-protein]details
Adenosine triphosphate + Holo-[carboxylase] + Carbonic acid unknown ADP + Phosphoric acid + Carboxybiotin-carboxyl-carrier proteindetails
Gene Name:
DTYMK
Uniprot ID:
P23919
Reactions
Adenosine triphosphate + 5-Thymidylic acid unknown ADP + dTDPdetails
Adenosine triphosphate + dUMP unknown ADP + dUDPdetails
Gene Name:
ENTPD1
Uniprot ID:
P49961
Reactions
Adenosine triphosphate + Water unknown Adenosine monophosphate + Phosphoric aciddetails
Adenosine triphosphate + Water unknown ADP + Phosphoric aciddetails
Gene Name:
ENTPD3
Uniprot ID:
O75355
Reactions
Adenosine triphosphate + Water unknown Adenosine monophosphate + Phosphoric aciddetails
Adenosine triphosphate + Water unknown ADP + Phosphoric aciddetails
Gene Name:
PON3
Uniprot ID:
Q15166
Gene Name:
UCK1
Uniprot ID:
Q9HA47
Reactions
Adenosine triphosphate + Uridine unknown ADP + Uridine 5'-monophosphatedetails
Adenosine triphosphate + Cytidine unknown ADP + Cytidine monophosphatedetails
5-Fluorouridine + Adenosine triphosphate unknown 5-Fluorouridine monophosphate + ADPdetails
Gene Name:
NME4
Uniprot ID:
O00746
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
NME1
Uniprot ID:
P15531
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
NME7
Uniprot ID:
Q9Y5B8
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
NME2
Uniprot ID:
P22392
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + protein L-histidine unknown ADP + protein N-phospho-L-histidinedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
NME3
Uniprot ID:
Q13232
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
NME6
Uniprot ID:
O75414
Reactions
Adenosine triphosphate + nucleoside diphosphate unknown ADP + nucleoside triphosphatedetails
Adenosine triphosphate + ADP unknown ADP + Adenosine triphosphatedetails
Adenosine triphosphate + Uridine 5'-diphosphate unknown ADP + Uridine triphosphatedetails
Adenosine triphosphate + Guanosine diphosphate unknown ADP + Guanosine triphosphatedetails
Adenosine triphosphate + CDP unknown ADP + Cytidine triphosphatedetails
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Adenosine triphosphate + dADP unknown ADP + Deoxyadenosine triphosphatedetails
Adenosine triphosphate + dGDP unknown ADP + dGTPdetails
Adenosine triphosphate + dTDP unknown ADP + Thymidine 5'-triphosphatedetails
Adenosine triphosphate + dCDP unknown ADP + dCTPdetails
Adenosine triphosphate + dUDP unknown ADP + Deoxyuridine triphosphatedetails
Adenosine triphosphate + dIDP unknown ADP + 2'-Deoxyinosine triphosphatedetails
Gene Name:
GCK
Uniprot ID:
P35557
Reactions
Adenosine triphosphate + D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + Beta-D-Glucose unknown ADP + Beta-D-Glucose 6-phosphatedetails
Adenosine triphosphate + Alpha-D-Glucose unknown ADP + Glucose 6-phosphatedetails
Gene Name:
HK3
Uniprot ID:
P52790
Reactions
Adenosine triphosphate + D-Galactose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphatedetails
Adenosine triphosphate + Beta-D-Glucose unknown ADP + Beta-D-Glucose 6-phosphatedetails
Adenosine triphosphate + Alpha-D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + Glucosamine unknown ADP + Glucosamine 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Gene Name:
HK2
Uniprot ID:
P52789
Reactions
Adenosine triphosphate + D-Galactose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphatedetails
Adenosine triphosphate + Beta-D-Glucose unknown ADP + Beta-D-Glucose 6-phosphatedetails
Adenosine triphosphate + Alpha-D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + Glucosamine unknown ADP + Glucosamine 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Gene Name:
HK1
Uniprot ID:
P19367
Reactions
Adenosine triphosphate + D-Galactose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphatedetails
Adenosine triphosphate + Beta-D-Glucose unknown ADP + Beta-D-Glucose 6-phosphatedetails
Adenosine triphosphate + Alpha-D-Glucose unknown ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + Glucosamine unknown ADP + Glucosamine 6-phosphatedetails
Adenosine triphosphate + D-Fructose unknown ADP + Beta-D-Fructose 6-phosphatedetails
Gene Name:
DGKQ
Uniprot ID:
P52824
Gene Name:
DGKA
Uniprot ID:
P23743
Gene Name:
DGKD
Uniprot ID:
Q16760
Gene Name:
DGKB
Uniprot ID:
Q9Y6T7
Gene Name:
DGKI
Uniprot ID:
O75912
Gene Name:
DGKZ
Uniprot ID:
Q13574
Gene Name:
FUK
Uniprot ID:
Q8N0W3
Reactions
Adenosine triphosphate + L-Fucose unknown ADP + Fucose 1-phosphatedetails
Gene Name:
PCCB
Uniprot ID:
P05166
Reactions
Adenosine triphosphate + Propionyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + S-Methylmalonyl-CoAdetails
Gene Name:
PCCA
Uniprot ID:
P05165
Reactions
Adenosine triphosphate + Propionyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + S-Methylmalonyl-CoAdetails
Gene Name:
FARSA
Uniprot ID:
Q9Y285
Reactions
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)details
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)details
Gene Name:
FARS2
Uniprot ID:
O95363
Reactions
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)details
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) unknown Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)details
Gene Name:
ALDH7A1
Uniprot ID:
P49419
Reactions
Aminoadipic acid + Adenosine triphosphate unknown L-2-Aminoadipate adenylate + Pyrophosphatedetails
Gene Name:
GART
Uniprot ID:
P22102
Reactions
Adenosine triphosphate + 5-Phosphoribosylamine + Glycine unknown ADP + Phosphoric acid + Glycineamideribotidedetails
Adenosine triphosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine unknown ADP + Phosphoric acid + 5-Aminoimidazole ribonucleotidedetails
Adenosine triphosphate + 5-Phosphoribosylamine + Glycine unknown ADP + Phosphoric acid + Glycineamideribotidedetails
Adenosine triphosphate + Phosphoribosylformylglycineamidine unknown ADP + Phosphoric acid + 5-Aminoimidazole ribonucleotidedetails
Gene Name:
GNE
Uniprot ID:
Q9Y223
Reactions
Adenosine triphosphate + N-acyl-D-mannosamine unknown ADP + N-acyl-D-mannosamine 6-phosphatedetails
Adenosine triphosphate + N-Acetylmannosamine unknown ADP + N-Acetyl-D-mannosamine 6-phosphatedetails
Gene Name:
RENBP
Uniprot ID:
P51606
Gene Name:
NMNAT1
Uniprot ID:
Q9HAN9
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
NMNAT3
Uniprot ID:
Q96T66
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
NMNAT2
Uniprot ID:
Q9BZQ4
Reactions
Adenosine triphosphate + beta-nicotinamide D-ribonucleotide unknown Pyrophosphate + NADdetails
Adenosine triphosphate + beta-nicotinate-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Adenosine triphosphate + nicotinate beta-D-ribonucleotide unknown Pyrophosphate + Nicotinic acid adenine dinucleotidedetails
Gene Name:
PAPSS1
Uniprot ID:
O43252
Reactions
Adenosine triphosphate + Oat gum unknown Pyrophosphate + Adenosine phosphosulfatedetails
Adenosine triphosphate + Adenosine phosphosulfate unknown ADP + Phosphoadenosine phosphosulfatedetails
Adenosine triphosphate + Adenylylselenate unknown ADP + 3-Phosphoadenylylselenatedetails
Adenosine triphosphate + Selenocystathionine unknown Pyrophosphate + Adenylylselenatedetails
Gene Name:
PAPSS2
Uniprot ID:
O95340
Reactions
Adenosine triphosphate + Oat gum unknown Pyrophosphate + Adenosine phosphosulfatedetails
Adenosine triphosphate + Adenosine phosphosulfate unknown ADP + Phosphoadenosine phosphosulfatedetails
Adenosine triphosphate + Adenylylselenate unknown ADP + 3-Phosphoadenylylselenatedetails
Adenosine triphosphate + Selenocystathionine unknown Pyrophosphate + Adenylylselenatedetails
Gene Name:
CPS1
Uniprot ID:
P31327
Reactions
Adenosine triphosphate + Ammonia + CO(2) + Water unknown ADP + Phosphoric acid + Carbamoyl phosphatedetails
Adenosine triphosphate + Ammonia + Carbon dioxide + Water unknown ADP + Phosphoric acid + Carbamoyl phosphatedetails
Gene Name:
MAT2A
Uniprot ID:
P31153
Reactions
Adenosine triphosphate + L-Methionine + Water unknown Phosphoric acid + Pyrophosphate + S-Adenosylmethioninedetails
Phosphoric acid + Pyrophosphate + S-Adenosylmethionine unknown Adenosine triphosphate + L-Methionine + Waterdetails
Adenosine triphosphate + Selenomethionine + Water unknown Phosphoric acid + Pyrophosphate + Se-Adenosylselenomethioninedetails
Gene Name:
MAT1A
Uniprot ID:
Q00266
Reactions
Adenosine triphosphate + L-Methionine + Water unknown Phosphoric acid + Pyrophosphate + S-Adenosylmethioninedetails
Phosphoric acid + Pyrophosphate + S-Adenosylmethionine unknown Adenosine triphosphate + L-Methionine + Waterdetails
Adenosine triphosphate + Selenomethionine + Water unknown Phosphoric acid + Pyrophosphate + Se-Adenosylselenomethioninedetails
Gene Name:
ITPA
Uniprot ID:
Q9BY32

Transporters

Gene Name:
ATP7B
Uniprot ID:
P35670
Gene Name:
ATP7A
Uniprot ID:
Q04656
Gene Name:
TAP1
Uniprot ID:
Q03518

Only showing the first 50 proteins. There are 1040 proteins in total.