Human Metabolome Database Version 3.5

Showing metabocard for Magnesium (HMDB00547)

Record Information
Version 3.5
Creation Date 2006-08-15 15:24:16 -0600
Update Date 2013-02-08 11:19:07 -0700
HMDB ID HMDB00547
Secondary Accession Numbers None
Metabolite Identification
Common Name Magnesium
Description Magnesium salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. Physiologically, it exists as an ion in the body. It is a component of both intra- and extracellular fluids and is excreted in the urine and feces. Deficiency causes irritability of the nervous system with tetany, vasodilatation, convulsions, tremors, depression, and psychotic behavior. Magnesium ion in large amounts is an ionic laxative, and magnesium sulfate (Epsom salts) is sometimes used for this purpose. So-called "milk of magnesia" is a water suspension of one of the few insoluble magnesium compounds, magnesium hydroxide; the undissolved particles give rise to its appearance and name. Milk of magnesia is a mild base, and is commonly used as an antacid.
Structure Thumb
Download: MOL | SDF | PDB | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. Magnesium
  2. Magnesium ions
Chemical Formula Mg
Average Molecular Weight 24.305
Monoisotopic Molecular Weight 23.985041898
IUPAC Name magnesium(2+) ion
Traditional IUPAC Name magnesium
CAS Registry Number 7439-95-4
SMILES [Mg++]
InChI Identifier InChI=1S/Mg/q+2
InChI Key JLVVSXFLKOJNIY-UHFFFAOYSA-N
Chemical Taxonomy
Kingdom Inorganic Compounds
Super Class Homogeneous Metal Compounds
Class Homogeneous Alkaline Earth Metal Compounds
Sub Class N/A
Other Descriptors
  • a cation(Cyc)
  • divalent metal cation(ChEBI)
  • magnesium cation(ChEBI)
  • monoatomic dication(ChEBI)
Substituents
  • N/A
Direct Parent Homogeneous Alkaline Earth Metal Compounds
Ontology
Status Detected and Quantified
Origin
  • Drug
  • Food
Biofunction
  • Enzyme co-factor
  • Essential minerals
  • Protein component
Application Not Available
Cellular locations
  • Cytoplasm (predicted from logP)
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point 651 °C Not Available
Boiling Point Not Available Not Available
Water Solubility Not Available Not Available
LogP Not Available Not Available
Predicted Properties
Property Value Source
LogP -0.57 ChemAxon
Hydrogen Acceptor Count 0 ChemAxon
Hydrogen Donor Count 0 ChemAxon
Polar Surface Area 0 A2 ChemAxon
Rotatable Bond Count 0 ChemAxon
Refractivity 0 ChemAxon
Polarizability 1.78 ChemAxon
Formal Charge 2 ChemAxon
Physiological Charge 2 ChemAxon
Spectra
Not Available
Biological Properties
Cellular Locations
  • Cytoplasm (predicted from logP)
Biofluid Locations
  • Blood
  • Cerebrospinal Fluid (CSF)
  • Urine
Tissue Location
  • Muscle
  • Skeletal Muscle
  • Lymphocyte
  • Erythrocyte
  • Kidney
  • Liver
  • Brain
  • Platelet
  • Hair
Pathways Not Available
Normal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified
717 +/- 74.3 uM Elderly (>65 years old) Both Normal
Blood Detected and Quantified
850.00 (700.00-1000.00) uM Adult (>18 years old) Both Normal
Blood Detected and Quantified
700.0 +/- 130.0 uM Newborn (0-30 days old) Both Normal
  • Geigy Scient...
Blood Detected and Quantified
780.0 +/- 50.0 uM Children (1-13 year old) Both Normal
  • Geigy Scient...
Blood Detected and Quantified
833.0 +/- 208.0 uM Adult (>18 years old) Female Normal
Blood Detected and Quantified
833.0 +/- 250.0 uM Adult (>18 years old) Male Normal
Cerebrospinal Fluid (CSF) Detected and Quantified
954 +/- 207 uM Adult (>18 years old) Not Specified Normal
Cerebrospinal Fluid (CSF) Detected and Quantified
890.0 (550.0-1230.0) uM Adult (>18 years old) Both Normal
  • Geigy Scient...
Urine Detected and Quantified
262 (42-1189) umol/mmol creatinine Adult (>18 years old) Both Comment Normal
Urine Detected and Quantified
355.0 +/- 98.0 umol/mmol creatinine Adult (>18 years old) Male Normal
  • Geigy Scient...
  • West Cadwell...
  • Basel, Switz...
Urine Detected and Quantified
289.0 +/- 92.0 umol/mmol creatinine Adult (>18 years old) Female Normal
  • Geigy Scient...
  • West Cadwell...
  • Basel, Switz...
Abnormal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified 1534 +/- 242 uM Adult (>18 years old) Both Multiple sclerosis
Blood Detected and Quantified 793 +/- 134 uM Adult (>18 years old) Both Parkinson's disease
Blood Detected and Quantified 220.00 (150.00-300.00) uM Children (1-13 year old) Both Primary Hypomagnesemia
Blood Detected and Quantified 763 +/- 100 uM Adult (>18 years old) Both Alzheimer's disease
Associated Disorders and Diseases
Disease References
Alzheimer's disease
  • Bocca B, Forte G, Petrucci F, Pino A, Marchione F, Bomboi G, Senofonte O, Giubilei F, Alimonti A: Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease. Ann Ist Super Sanita. 2005;41(2):197-203. Pubmed: 16244393 Link_out
      Multiple sclerosis
      • Forte G, Visconti A, Santucci S, Ghazaryan A, Figa-Talamanca L, Cannoni S, Bocca B, Pino A, Violante N, Alimonti A, Salvetti M, Ristori G: Quantification of chemical elements in blood of patients affected by multiple sclerosis. Ann Ist Super Sanita. 2005;41(2):213-6. Pubmed: 16244395 Link_out
          Parkinson's disease
          • Forte G, Alimonti A, Pino A, Stanzione P, Brescianini S, Brusa L, Sancesario G, Violante N, Bocca B: Metals and oxidative stress in patients with Parkinson's disease. Ann Ist Super Sanita. 2005;41(2):189-95. Pubmed: 16244392 Link_out
              Primary hypomagnesemia
                  Associated OMIM IDs
                  DrugBank ID Not Available
                  DrugBank Metabolite ID Not Available
                  Phenol Explorer Compound ID Not Available
                  Phenol Explorer Metabolite ID Not Available
                  FoodDB ID FDB003518
                  KNApSAcK ID Not Available
                  Chemspider ID 865 Link_out
                  KEGG Compound ID C00305 Link_out
                  BioCyc ID 13-HYDROXY-MAGNESIUM-PROTOPORP Link_out
                  BiGG ID Not Available
                  Wikipedia Link Magnesium Link_out
                  NuGOwiki Link HMDB00547 Link_out
                  Metagene Link HMDB00547 Link_out
                  METLIN ID Not Available
                  PubChem Compound 888 Link_out
                  PDB ID MG Link_out
                  ChEBI ID 18420 Link_out
                  References
                  Synthesis Reference Not Available
                  Material Safety Data Sheet (MSDS) Download (PDF)
                  General References
                  1. Rakicioglu N, Samur G, Topcu A, Topcu AA: The effect of Ramadan on maternal nutrition and composition of breast milk. Pediatr Int. 2006 Jun;48(3):278-83. Pubmed: 16732795 Link_out
                  2. Fowler AJ, Moskowitz DG, Wong A, Cohen SP, Williams ML, Heyman MB: Nutritional status and gastrointestinal structure and function in children with ichthyosis and growth failure. J Pediatr Gastroenterol Nutr. 2004 Feb;38(2):164-9. Pubmed: 14734878 Link_out
                  3. Siqueira WL, de Oliveira E, Mustacchi Z, Nicolau J: Electrolyte concentrations in saliva of children aged 6-10 years with Down syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jul;98(1):76-9. Pubmed: 15243474 Link_out
                  4. Abbasciano V, Sartori S, Trevisani L, Girometti R, Ranzini M, Nielsen I, Mazzotta D, Vecchiatti G, Bononi A, Guglielmini C: Comparison of magnesium concentration in serum, erythrocytes and gastric tissue in two groups of patients affected by chronic gastritis, Helicobacter pylori negative and positive. Magnes Res. 2003 Dec;16(4):281-6. Pubmed: 14979638 Link_out
                  5. Kielczykowska M, Pasternak K, Musik I: The influence of lithium on calcium and magnesium homeostasis in serum and tissues of rats. Ann Univ Mariae Curie Sklodowska [Med]. 2003;58(2):281-4. Pubmed: 15323205 Link_out
                  6. Resnick LM, Barbagallo M, Bardicef M, Bardicef O, Sorokin Y, Evelhoch J, Dominguez LJ, Mason BA, Cotton DB: Cellular-free magnesium depletion in brain and muscle of normal and preeclamptic pregnancy: a nuclear magnetic resonance spectroscopic study. Hypertension. 2004 Sep;44(3):322-6. Epub 2004 Jul 19. Pubmed: 15262910 Link_out
                  7. Korycinska A, Dabrowski W, Rzecki Z, Dragan M, Pozarowski P, Wronska J, Stazka J, Pasternak K, Rolinski J: The degree of lymphocytic mitochondrial transmembrane potential and blood magnesium concentrations during coronary artery bypass grafting. Magnes Res. 2005 Dec;18(4):253-60. Pubmed: 16548140 Link_out
                  8. Wang FJ, Cao J, Ma LP, Jin ZX: [Study on cellular and serum concentration of calcium and magnesium in peripheral blood cells of cirrhosis] Zhonghua Gan Zang Bing Za Zhi. 2004 Mar;12(3):144-7. Pubmed: 15059297 Link_out
                  9. Kedzierska E: [Concentrations of selected bioelements and toxic metals and their influence on health status of children and youth residing in Szczecin] Ann Acad Med Stetin. 2003;49:131-43. Pubmed: 15552844 Link_out
                  10. Mendez DR, Corbett R, Macias C, Laptook A: Total and ionized plasma magnesium concentrations in children after traumatic brain injury. Pediatr Res. 2005 Mar;57(3):347-52. Epub 2004 Dec 7. Pubmed: 15585675 Link_out
                  11. Bologa C, Rusu M, Ianovici N, Tetraru C, Hurjui J, Petris O, Lionte C: [Role of calcium and magnesium ions in cerebrospinal fluid in alcoholic-traumatic coma] Rev Med Chir Soc Med Nat Iasi. 2003 Oct-Dec;107(4):809-12. Pubmed: 14756024 Link_out
                  12. Nielsen FH, Milne DB: A moderately high intake compared to a low intake of zinc depresses magnesium balance and alters indices of bone turnover in postmenopausal women. Eur J Clin Nutr. 2004 May;58(5):703-10. Pubmed: 15116072 Link_out
                  13. Miyamoto Y, Yamamoto H, Murakami H, Kamiyama N, Fukuda M: Studies on cerebrospinal fluid ionized calcium and magnesium concentrations in convulsive children. Pediatr Int. 2004 Aug;46(4):394-7. Pubmed: 15310301 Link_out
                  14. Guo H, Lee JD, Guo M, Lu Y, Tang F, Ueda T: Status of intracellular and extracellular magnesium concentration in patients with cardiac syndrome X. Acta Cardiol. 2005 Jun;60(3):259-63. Pubmed: 15999464 Link_out
                  15. Wang W, Kumar P, Minhas S, Ralph D: Proposals or findings for a new approach about how to define and diagnose premature ejaculation. Eur Urol. 2005 Sep;48(3):418-23. Pubmed: 15967566 Link_out
                  16. Guo H, Cheng J, Lee JD, Ueda T, Shan J, Wang J: Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004 May;29(3):299-303. Pubmed: 15167956 Link_out
                  17. Bryant RE, Crouse R, Deagen JT: Zinc, iron, copper, selenium, lactoferrin, and ferritin in human pus. Am J Med Sci. 2004 Feb;327(2):73-6. Pubmed: 14770022 Link_out
                  18. Gortzak-Uzan L, Mezad D, Smolin A, Friger M, Huleihel M, Hallak M: Increasing amniotic fluid magnesium concentrations with stable maternal serum levels: a prospective clinical trial. J Reprod Med. 2005 Nov;50(11):817-20. Pubmed: 16419627 Link_out
                  19. Postnikova LB, Alekseeva OP, Kubysheva NI, Gorshkova TN, Ishanova OS: [Significance of biochemical parameters of saliva in the diagnosis of chronic obstructive pulmonary disease at exacerbation] Klin Lab Diagn. 2004 Oct;(10):16-8. Pubmed: 15584394 Link_out
                  20. Simsek E, Karabay M, Kocabay K: Assessment of magnesium status in newly diagnosed diabetic children: measurement of erythrocyte magnesium level and magnesium tolerance testing. Turk J Pediatr. 2005 Apr-Jun;47(2):132-7. Pubmed: 16052852 Link_out

                  Enzymes

                  Show all enzymes and transporters Important Only showing the first 50 enzymes. There are 463 enzymes in total.

                  Name: UMP-CMP kinase
                  Reactions: Not Available
                  Gene Name: CMPK1
                  Uniprot ID: P30085 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Cytosolic 5'-nucleotidase 1B
                  Reactions: Not Available
                  Gene Name: NT5C1B
                  Uniprot ID: Q96P26 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Cytosolic 5'-nucleotidase 1A
                  Reactions: Not Available
                  Gene Name: NT5C1A
                  Uniprot ID: Q9BXI3 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: 5'(3')-deoxyribonucleotidase, cytosolic type
                  Reactions: Not Available
                  Gene Name: NT5C
                  Uniprot ID: Q8TCD5 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: 5'(3')-deoxyribonucleotidase, mitochondrial
                  Reactions: Not Available
                  Gene Name: NT5M
                  Uniprot ID: Q9NPB1 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Ectonucleoside triphosphate diphosphohydrolase 1
                  Reactions: Not Available
                  Gene Name: ENTPD1
                  Uniprot ID: P49961 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Ectonucleoside triphosphate diphosphohydrolase 3
                  Reactions: Not Available
                  Gene Name: ENTPD3
                  Uniprot ID: O75355 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Alkaline phosphatase, placental type
                  Reactions: Not Available
                  Gene Name: ALPP
                  Uniprot ID: P05187 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Intestinal-type alkaline phosphatase
                  Reactions: Not Available
                  Gene Name: ALPI
                  Uniprot ID: P09923 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Alkaline phosphatase, tissue-nonspecific isozyme
                  Reactions: Not Available
                  Gene Name: ALPL
                  Uniprot ID: P05186 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Alkaline phosphatase, placental-like
                  Reactions: Not Available
                  Gene Name: ALPPL2
                  Uniprot ID: P10696 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase, mitochondrial
                  Reactions: Not Available
                  Gene Name: NME4
                  Uniprot ID: O00746 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase A
                  Reactions: Not Available
                  Gene Name: NME1
                  Uniprot ID: P15531 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase 7
                  Reactions: Not Available
                  Gene Name: NME7
                  Uniprot ID: Q9Y5B8 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase B
                  Reactions: Not Available
                  Gene Name: NME2
                  Uniprot ID: P22392 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase 3
                  Reactions: Not Available
                  Gene Name: NME3
                  Uniprot ID: Q13232 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nucleoside diphosphate kinase 6
                  Reactions: Not Available
                  Gene Name: NME6
                  Uniprot ID: O75414 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Dimethylaniline monooxygenase [N-oxide-forming] 2
                  Reactions: Not Available
                  Gene Name: FMO2
                  Uniprot ID: Q99518 Link_out
                  Protein Sequence: FASTA
                  Name: Squalene synthase
                  Reactions: Not Available
                  Gene Name: FDFT1
                  Uniprot ID: P37268 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Catechol O-methyltransferase
                  Reactions: Not Available
                  Gene Name: COMT
                  Uniprot ID: P21964 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Arylsulfatase A
                  Reactions: Not Available
                  Gene Name: ARSA
                  Uniprot ID: P15289 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: 6-phosphogluconolactonase
                  Reactions: Not Available
                  Gene Name: PGLS
                  Uniprot ID: O95336 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: GDH/6PGL endoplasmic bifunctional protein
                  Reactions: Not Available
                  Gene Name: H6PD
                  Uniprot ID: O95479 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Amidophosphoribosyltransferase
                  Reactions: Not Available
                  Gene Name: PPAT
                  Uniprot ID: Q06203 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nicotinamide mononucleotide adenylyltransferase 1
                  Reactions: Not Available
                  Gene Name: NMNAT1
                  Uniprot ID: Q9HAN9 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Nicotinamide mononucleotide adenylyltransferase 2
                  Reactions: Not Available
                  Gene Name: NMNAT2
                  Uniprot ID: Q9BZQ4 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: 3'(2'),5'-bisphosphate nucleotidase 1
                  Reactions: Not Available
                  Gene Name: BPNT1
                  Uniprot ID: O95861 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Inositol polyphosphate 1-phosphatase
                  Reactions: Not Available
                  Gene Name: INPP1
                  Uniprot ID: P49441 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: ADP-dependent glucokinase
                  Reactions: Not Available
                  Gene Name: ADPGK
                  Uniprot ID: Q9BRR6 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: S-adenosylmethionine synthase isoform type-2
                  Reactions: Not Available
                  Gene Name: MAT2A
                  Uniprot ID: P31153 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: S-adenosylmethionine synthase isoform type-1
                  Reactions: Not Available
                  Gene Name: MAT1A
                  Uniprot ID: Q00266 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Inosine triphosphate pyrophosphatase
                  Reactions: Not Available
                  Gene Name: ITPA
                  Uniprot ID: Q9BY32 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
                  Reactions: Not Available
                  Gene Name: DUT
                  Uniprot ID: P33316 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Deoxyribonuclease-1
                  Reactions: Not Available
                  Gene Name: DNASE1
                  Uniprot ID: P24855 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Hypoxanthine-guanine phosphoribosyltransferase
                  Reactions: Not Available
                  Gene Name: HPRT1
                  Uniprot ID: P00492 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Ribose-phosphate pyrophosphokinase 3
                  Reactions: Not Available
                  Gene Name: PRPS1L1
                  Uniprot ID: P21108 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Long-chain-fatty-acid--CoA ligase 4
                  Reactions: Not Available
                  Gene Name: ACSL4
                  Uniprot ID: O60488 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
                  Reactions: Not Available
                  Gene Name: PDE8A
                  Uniprot ID: O60658 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Long-chain-fatty-acid--CoA ligase 1
                  Reactions: Not Available
                  Gene Name: ACSL1
                  Uniprot ID: P33121 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Bis(5'-adenosyl)-triphosphatase
                  Reactions: Not Available
                  Gene Name: FHIT
                  Uniprot ID: P49789 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Long-chain-fatty-acid--CoA ligase 6
                  Reactions: Not Available
                  Gene Name: ACSL6
                  Uniprot ID: Q9UKU0 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: ADP-sugar pyrophosphatase
                  Reactions: Not Available
                  Gene Name: NUDT5
                  Uniprot ID: Q9UKK9 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Ribose-phosphate pyrophosphokinase 1
                  Reactions: Not Available
                  Gene Name: PRPS1
                  Uniprot ID: P60891 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Ribose-phosphate pyrophosphokinase 2
                  Reactions: Not Available
                  Gene Name: PRPS2
                  Uniprot ID: P11908 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
                  Reactions: Not Available
                  Gene Name: PDE4D
                  Uniprot ID: Q08499 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: ADP-ribose pyrophosphatase, mitochondrial
                  Reactions: Not Available
                  Gene Name: NUDT9
                  Uniprot ID: Q9BW91 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Adenosine kinase
                  Reactions: Not Available
                  Gene Name: ADK
                  Uniprot ID: P55263 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Long-chain-fatty-acid--CoA ligase 5
                  Reactions: Not Available
                  Gene Name: ACSL5
                  Uniprot ID: Q9ULC5 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Long-chain-fatty-acid--CoA ligase 3
                  Reactions: Not Available
                  Gene Name: ACSL3
                  Uniprot ID: O95573 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: cGMP-specific 3',5'-cyclic phosphodiesterase
                  Reactions: Not Available
                  Gene Name: PDE5A
                  Uniprot ID: O76074 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA