Human Metabolome Database Version 3.5

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Showing metabocard for Magnesium (HMDB00547)

enzymes (463)

Blood
Urine

Record Information

Version

3.5

Creation Date

2006-08-15 15:24:16 -0600

Update Date

2013-02-08 11:19:07 -0700

HMDB ID

HMDB00547

Secondary Accession Numbers

None

Metabolite Identification

Common Name

Magnesium

Description

Magnesium salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. Physiologically, it exists as an ion in the body. It is a component of both intra- and extracellular fluids and is excreted in the urine and feces. Deficiency causes irritability of the nervous system with tetany, vasodilatation, convulsions, tremors, depression, and psychotic behavior. Magnesium ion in large amounts is an ionic laxative, and magnesium sulfate (Epsom salts) is sometimes used for this purpose. So-called "milk of magnesia" is a water suspension of one of the few insoluble magnesium compounds, magnesium hydroxide; the undissolved particles give rise to its appearance and name. Milk of magnesia is a mild base, and is commonly used as an antacid.

Structure

Download: MOL | SDF | SMILES | InChI
Display: 2D Structure | 3D Structure

Synonyms

Magnesium
Magnesium ions

Chemical Formula

Average Molecular Weight

24.305

Monoisotopic Molecular Weight

23.985041898

IUPAC Name

magnesium(2+) ion

Traditional IUPAC Name

magnesium

CAS Registry Number

7439-95-4

SMILES

[Mg++]

InChI Identifier

InChI=1S/Mg/q+2

InChI Key

JLVVSXFLKOJNIY-UHFFFAOYSA-N

Chemical Taxonomy

Kingdom

Inorganic Compounds

Super Class

Homogeneous Metal Compounds

Class

Homogeneous Alkaline Earth Metal Compounds

Sub Class

N/A

Other Descriptors

a cation(Cyc)
divalent metal cation(ChEBI)
magnesium cation(ChEBI)
monoatomic dication(ChEBI)

Substituents

Direct Parent

Homogeneous Alkaline Earth Metal Compounds

Ontology

Status

Detected and Quantified

Origin

Food

Drug

Biofunction

Enzyme co-factor
Essential minerals
Protein component

Application

Not Available

Cellular locations

Cytoplasm (predicted from logP)

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	651 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
LogP	-0.57	ChemAxon
Hydrogen Acceptor Count	0	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	0 A²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	0	ChemAxon
Polarizability	1.78	ChemAxon
Formal Charge	2	ChemAxon
Physiological Charge	2	ChemAxon

Spectra

Not Available

Biological Properties

Cellular Locations

Cytoplasm (predicted from logP)

Biofluid Locations

Blood
Cerebrospinal Fluid (CSF)
Urine

Tissue Location

Muscle
Skeletal Muscle
Lymphocyte
Erythrocyte
Kidney
Liver
Brain
Platelet
Hair

Pathways

Not Available

Normal Concentrations

Biofluid	Status	Value	Age	Sex	Condition	Comments
Blood	Detected and Quantified	717 +/- 74.3 uM	Elderly (>65 years old)	Both	Normal	Not Available
Blood	Detected and Quantified	700.0 +/- 130.0 uM	Newborn (0-30 days old)	Both	Normal	Not Available
Blood	Detected and Quantified	780.0 +/- 50.0 uM	Children (1-13 year old)	Both	Normal	Not Available
Blood	Detected and Quantified	833.0 +/- 208.0 uM	Adult (>18 years old)	Female	Normal	Not Available
Blood	Detected and Quantified	833.0 +/- 250.0 uM	Adult (>18 years old)	Male	Normal	Not Available
Cerebrospinal Fluid (CSF)	Detected and Quantified	954 +/- 207 uM	Adult (>18 years old)	Not Specified	Normal	Not Available
Cerebrospinal Fluid (CSF)	Detected and Quantified	890.0 (550.0-1230.0) uM	Adult (>18 years old)	Both	Normal	Not Available
Urine	Detected and Quantified	262 (42-1189) umol/mmol creatinine	Adult (>18 years old)	Both	Normal	by ICP MS
Urine	Detected and Quantified	355.0 +/- 98.0 umol/mmol creatinine	Adult (>18 years old)	Male	Normal	Not Available
Urine	Detected and Quantified	289.0 +/- 92.0 umol/mmol creatinine	Adult (>18 years old)	Female	Normal	Not Available

Abnormal Concentrations

Biofluid	Status	Value	Age	Sex	Condition	Comments
Blood	Detected and Quantified	1534 +/- 242 uM	Adult (>18 years old)	Both	Multiple sclerosis	Not Available
Blood	Detected and Quantified	793 +/- 134 uM	Adult (>18 years old)	Both	Parkinson's disease	Not Available
Blood	Detected and Quantified	220.00 (150.00-300.00) uM	Adult (>18 years old)	Both	Primary Hypomagnesemia	Not Available
Blood	Detected and Quantified	850.00 (700.00-1000.00) uM	Adult (>18 years old)	Both	Primary hypomagnesemia	Not Available
Blood	Detected and Quantified	763 +/- 100 uM	Adult (>18 years old)	Both	Alzheimer's disease	Not Available

Associated Disorders and Diseases

Disease References

Alzheimer's disease
Bocca B, Forte G, Petrucci F, Pino A, Marchione F, Bomboi G, Senofonte O, Giubilei F, Alimonti A: Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease. Ann Ist Super Sanita. 2005;41(2):197-203. Pubmed: 16244393
Multiple sclerosis
Forte G, Visconti A, Santucci S, Ghazaryan A, Figa-Talamanca L, Cannoni S, Bocca B, Pino A, Violante N, Alimonti A, Salvetti M, Ristori G: Quantification of chemical elements in blood of patients affected by multiple sclerosis. Ann Ist Super Sanita. 2005;41(2):213-6. Pubmed: 16244395
Parkinson's disease
Forte G, Alimonti A, Pino A, Stanzione P, Brescianini S, Brusa L, Sancesario G, Violante N, Bocca B: Metals and oxidative stress in patients with Parkinson's disease. Ann Ist Super Sanita. 2005;41(2):189-95. Pubmed: 16244392
Primary hypomagnesemia
http://www.metagene.de/program/d.prg?mp=PRIMARY%20HYPOMAGNESEMIA

Associated OMIM IDs

104300 (Alzheimer's disease)
126200 (Multiple sclerosis)
168600 (Parkinson's disease)
248250 (Primary hypomagnesemia)

External Links

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

Phenol Explorer Metabolite ID

Not Available

FoodDB ID

FDB003518

KNApSAcK ID

Not Available

Chemspider ID

865

KEGG Compound ID

C00305

BioCyc ID

13-HYDROXY-MAGNESIUM-PROTOPORP Link_out

BiGG ID

Not Available

Wikipedia Link

Magnesium

NuGOwiki Link

HMDB00547

Metagene Link

HMDB00547

METLIN ID

Not Available

PubChem Compound

888

PDB ID

ChEBI ID

18420

References

Synthesis Reference

Not Available

Material Safety Data Sheet (MSDS)

Download (PDF)

General References

Rakicioglu N, Samur G, Topcu A, Topcu AA: The effect of Ramadan on maternal nutrition and composition of breast milk. Pediatr Int. 2006 Jun;48(3):278-83. Pubmed: 16732795
Fowler AJ, Moskowitz DG, Wong A, Cohen SP, Williams ML, Heyman MB: Nutritional status and gastrointestinal structure and function in children with ichthyosis and growth failure. J Pediatr Gastroenterol Nutr. 2004 Feb;38(2):164-9. Pubmed: 14734878
Siqueira WL, de Oliveira E, Mustacchi Z, Nicolau J: Electrolyte concentrations in saliva of children aged 6-10 years with Down syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jul;98(1):76-9. Pubmed: 15243474
Abbasciano V, Sartori S, Trevisani L, Girometti R, Ranzini M, Nielsen I, Mazzotta D, Vecchiatti G, Bononi A, Guglielmini C: Comparison of magnesium concentration in serum, erythrocytes and gastric tissue in two groups of patients affected by chronic gastritis, Helicobacter pylori negative and positive. Magnes Res. 2003 Dec;16(4):281-6. Pubmed: 14979638
Kielczykowska M, Pasternak K, Musik I: The influence of lithium on calcium and magnesium homeostasis in serum and tissues of rats. Ann Univ Mariae Curie Sklodowska [Med]. 2003;58(2):281-4. Pubmed: 15323205
Resnick LM, Barbagallo M, Bardicef M, Bardicef O, Sorokin Y, Evelhoch J, Dominguez LJ, Mason BA, Cotton DB: Cellular-free magnesium depletion in brain and muscle of normal and preeclamptic pregnancy: a nuclear magnetic resonance spectroscopic study. Hypertension. 2004 Sep;44(3):322-6. Epub 2004 Jul 19. Pubmed: 15262910
Korycinska A, Dabrowski W, Rzecki Z, Dragan M, Pozarowski P, Wronska J, Stazka J, Pasternak K, Rolinski J: The degree of lymphocytic mitochondrial transmembrane potential and blood magnesium concentrations during coronary artery bypass grafting. Magnes Res. 2005 Dec;18(4):253-60. Pubmed: 16548140
Wang FJ, Cao J, Ma LP, Jin ZX: [Study on cellular and serum concentration of calcium and magnesium in peripheral blood cells of cirrhosis] Zhonghua Gan Zang Bing Za Zhi. 2004 Mar;12(3):144-7. Pubmed: 15059297
Kedzierska E: [Concentrations of selected bioelements and toxic metals and their influence on health status of children and youth residing in Szczecin] Ann Acad Med Stetin. 2003;49:131-43. Pubmed: 15552844
Mendez DR, Corbett R, Macias C, Laptook A: Total and ionized plasma magnesium concentrations in children after traumatic brain injury. Pediatr Res. 2005 Mar;57(3):347-52. Epub 2004 Dec 7. Pubmed: 15585675
Bologa C, Rusu M, Ianovici N, Tetraru C, Hurjui J, Petris O, Lionte C: [Role of calcium and magnesium ions in cerebrospinal fluid in alcoholic-traumatic coma] Rev Med Chir Soc Med Nat Iasi. 2003 Oct-Dec;107(4):809-12. Pubmed: 14756024
Nielsen FH, Milne DB: A moderately high intake compared to a low intake of zinc depresses magnesium balance and alters indices of bone turnover in postmenopausal women. Eur J Clin Nutr. 2004 May;58(5):703-10. Pubmed: 15116072
Miyamoto Y, Yamamoto H, Murakami H, Kamiyama N, Fukuda M: Studies on cerebrospinal fluid ionized calcium and magnesium concentrations in convulsive children. Pediatr Int. 2004 Aug;46(4):394-7. Pubmed: 15310301
Guo H, Lee JD, Guo M, Lu Y, Tang F, Ueda T: Status of intracellular and extracellular magnesium concentration in patients with cardiac syndrome X. Acta Cardiol. 2005 Jun;60(3):259-63. Pubmed: 15999464
Wang W, Kumar P, Minhas S, Ralph D: Proposals or findings for a new approach about how to define and diagnose premature ejaculation. Eur Urol. 2005 Sep;48(3):418-23. Pubmed: 15967566
Guo H, Cheng J, Lee JD, Ueda T, Shan J, Wang J: Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004 May;29(3):299-303. Pubmed: 15167956
Bryant RE, Crouse R, Deagen JT: Zinc, iron, copper, selenium, lactoferrin, and ferritin in human pus. Am J Med Sci. 2004 Feb;327(2):73-6. Pubmed: 14770022
Gortzak-Uzan L, Mezad D, Smolin A, Friger M, Huleihel M, Hallak M: Increasing amniotic fluid magnesium concentrations with stable maternal serum levels: a prospective clinical trial. J Reprod Med. 2005 Nov;50(11):817-20. Pubmed: 16419627
Postnikova LB, Alekseeva OP, Kubysheva NI, Gorshkova TN, Ishanova OS: [Significance of biochemical parameters of saliva in the diagnosis of chronic obstructive pulmonary disease at exacerbation] Klin Lab Diagn. 2004 Oct;(10):16-8. Pubmed: 15584394
Simsek E, Karabay M, Kocabay K: Assessment of magnesium status in newly diagnosed diabetic children: measurement of erythrocyte magnesium level and magnesium tolerance testing. Turk J Pediatr. 2005 Apr-Jun;47(2):132-7. Pubmed: 16052852

Enzymes

Name:	UMP-CMP kinase
Reactions:	ATP + (d)CMP = ADP + (d)CDP [RN:R00512 R01665]
Gene Name:	CMPK1
Uniprot ID:	P30085
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cytosolic 5'-nucleotidase 1B
Reactions:	a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297]
Gene Name:	NT5C1B
Uniprot ID:	Q96P26
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cytosolic 5'-nucleotidase 1A
Reactions:	a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297]
Gene Name:	NT5C1A
Uniprot ID:	Q9BXI3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5'(3')-deoxyribonucleotidase, cytosolic type
Reactions:
Gene Name:	NT5C
Uniprot ID:	Q8TCD5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5'(3')-deoxyribonucleotidase, mitochondrial
Reactions:
Gene Name:	NT5M
Uniprot ID:	Q9NPB1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 1
Reactions:	ATP + 2 H2O = AMP + 2 phosphate [RN:R00085]
Gene Name:	ENTPD1
Uniprot ID:	P49961
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 3
Reactions:	ATP + 2 H2O = AMP + 2 phosphate [RN:R00085]
Gene Name:	ENTPD3
Uniprot ID:	O75355
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Alkaline phosphatase, placental type
Reactions:	a phosphate monoester + H2O = an alcohol + phosphate [RN:R00626]
Gene Name:	ALPP
Uniprot ID:	P05187
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Intestinal-type alkaline phosphatase
Reactions:	a phosphate monoester + H2O = an alcohol + phosphate [RN:R00626]
Gene Name:	ALPI
Uniprot ID:	P09923
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Alkaline phosphatase, tissue-nonspecific isozyme
Reactions:	a phosphate monoester + H2O = an alcohol + phosphate [RN:R00626]
Gene Name:	ALPL
Uniprot ID:	P05186
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Alkaline phosphatase, placental-like
Reactions:	a phosphate monoester + H2O = an alcohol + phosphate [RN:R00626]
Gene Name:	ALPPL2
Uniprot ID:	P10696
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase, mitochondrial
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME4
Uniprot ID:	O00746
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase A
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME1
Uniprot ID:	P15531
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase 7
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME7
Uniprot ID:	Q9Y5B8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase B
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME2
Uniprot ID:	P22392
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase 3
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME3
Uniprot ID:	Q13232
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate kinase 6
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME6
Uniprot ID:	O75414
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dimethylaniline monooxygenase [N-oxide-forming] 2
Reactions:	N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O [RN:R03344]
Gene Name:	FMO2
Uniprot ID:	Q99518
Protein Sequence:	FASTA

Name:	Squalene synthase
Reactions:	(1) (1a) 2 farnesyl diphosphate = diphosphate + presqualene diphosphate [RN:R00702] (2) (1b) presqualene diphosphate + NAD(P)H + H+ = squalene + diphosphate + NAD(P)+ [RN:R02872]
Gene Name:	FDFT1
Uniprot ID:	P37268
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Catechol O-methyltransferase
Reactions:	S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol [RN:R07330]
Gene Name:	COMT
Uniprot ID:	P21964
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Arylsulfatase A
Reactions:	a cerebroside 3-sulfate + H2O = a cerebroside + sulfate [RN:R04856 R06280]
Gene Name:	ARSA
Uniprot ID:	P15289
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	6-phosphogluconolactonase
Reactions:	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate [RN:R02035]
Gene Name:	PGLS
Uniprot ID:	O95336
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	GDH/6PGL endoplasmic bifunctional protein
Reactions:	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate [RN:R02035]
Gene Name:	H6PD
Uniprot ID:	O95479
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Amidophosphoribosyltransferase
Reactions:	5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O [RN:R01072]
Gene Name:	PPAT
Uniprot ID:	Q06203
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nicotinamide mononucleotide adenylyltransferase 1
Reactions:	ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+ [RN:R03005]
Gene Name:	NMNAT1
Uniprot ID:	Q9HAN9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nicotinamide mononucleotide adenylyltransferase 2
Reactions:	ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+ [RN:R03005]
Gene Name:	NMNAT2
Uniprot ID:	Q9BZQ4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	3'(2'),5'-bisphosphate nucleotidase 1
Reactions:	adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate [RN:R00188]
Gene Name:	BPNT1
Uniprot ID:	O95861
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inositol polyphosphate 1-phosphatase
Reactions:	1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate [RN:R03393]
Gene Name:	INPP1
Uniprot ID:	P49441
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ADP-dependent glucokinase
Reactions:	ADP + D-glucose = AMP + D-glucose 6-phosphate [RN:R05804]
Gene Name:	ADPGK
Uniprot ID:	Q9BRR6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	S-adenosylmethionine synthase isoform type-2
Reactions:	ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine [RN:R00177]
Gene Name:	MAT2A
Uniprot ID:	P31153
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	S-adenosylmethionine synthase isoform type-1
Reactions:	ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine [RN:R00177]
Gene Name:	MAT1A
Uniprot ID:	Q00266
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inosine triphosphate pyrophosphatase
Reactions:	a nucleoside triphosphate + H2O = a nucleotide + diphosphate [RN:R01532]
Gene Name:	ITPA
Uniprot ID:	Q9BY32
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Reactions:	dUTP + H2O = dUMP + diphosphate [RN:R02100]
Gene Name:	DUT
Uniprot ID:	P33316
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Deoxyribonuclease-1
Reactions:	Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
Gene Name:	DNASE1
Uniprot ID:	P24855
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Hypoxanthine-guanine phosphoribosyltransferase
Reactions:	IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R01132]
Gene Name:	HPRT1
Uniprot ID:	P00492
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribose-phosphate pyrophosphokinase 3
Reactions:	ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R01049]
Gene Name:	PRPS1L1
Uniprot ID:	P21108
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Long-chain-fatty-acid--CoA ligase 4
Reactions:	ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390]
Gene Name:	ACSL4
Uniprot ID:	O60488
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Reactions:	nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259]
Gene Name:	PDE8A
Uniprot ID:	O60658
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Long-chain-fatty-acid--CoA ligase 1
Reactions:	ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390]
Gene Name:	ACSL1
Uniprot ID:	P33121
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bis(5'-adenosyl)-triphosphatase
Reactions:	P1,P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP [RN:R00187]
Gene Name:	FHIT
Uniprot ID:	P49789
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Long-chain-fatty-acid--CoA ligase 6
Reactions:	ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390]
Gene Name:	ACSL6
Uniprot ID:	Q9UKU0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ADP-sugar pyrophosphatase
Reactions:	ADP-ribose + H2O = AMP + D-ribose 5-phosphate [RN:R01054]
Gene Name:	NUDT5
Uniprot ID:	Q9UKK9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribose-phosphate pyrophosphokinase 1
Reactions:	ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R01049]
Gene Name:	PRPS1
Uniprot ID:	P60891
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribose-phosphate pyrophosphokinase 2
Reactions:	ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R01049]
Gene Name:	PRPS2
Uniprot ID:	P11908
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Reactions:	nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259]
Gene Name:	PDE4D
Uniprot ID:	Q08499
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ADP-ribose pyrophosphatase, mitochondrial
Reactions:	ADP-ribose + H2O = AMP + D-ribose 5-phosphate [RN:R01054]
Gene Name:	NUDT9
Uniprot ID:	Q9BW91
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenosine kinase
Reactions:	ATP + adenosine = ADP + AMP [RN:R00185]
Gene Name:	ADK
Uniprot ID:	P55263
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Long-chain-fatty-acid--CoA ligase 5
Reactions:	ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390]
Gene Name:	ACSL5
Uniprot ID:	Q9ULC5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Long-chain-fatty-acid--CoA ligase 3
Reactions:	ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390]
Gene Name:	ACSL3
Uniprot ID:	O95573
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	cGMP-specific 3',5'-cyclic phosphodiesterase
Reactions:	guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234]
Gene Name:	PDE5A
Uniprot ID:	O76074
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 7
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY7
Uniprot ID:	P51828
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 4
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY4
Uniprot ID:	Q8NFM4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 6
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY6
Uniprot ID:	O43306
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 5
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY5
Uniprot ID:	O95622
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 8
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY8
Uniprot ID:	P40145
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 9
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY9
Uniprot ID:	O60503
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 3
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY3
Uniprot ID:	O60266
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 1
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY1
Uniprot ID:	Q08828
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Fumarylacetoacetase
Reactions:	4-fumarylacetoacetate + H2O = acetoacetate + fumarate [RN:R01364]
Gene Name:	FAH
Uniprot ID:	P16930
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	6-phosphofructokinase type C
Reactions:	ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756]
Gene Name:	PFKP
Uniprot ID:	Q01813
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA-directed RNA polymerase II subunit RPB2
Reactions:	nucleoside triphosphate + RNAn = diphosphate + RNAn+1 [RN:R00444]
Gene Name:	POLR2B
Uniprot ID:	P30876
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA-directed RNA polymerase II subunit RPB1
Reactions:	nucleoside triphosphate + RNAn = diphosphate + RNAn+1 [RN:R00444]
Gene Name:	POLR2A
Uniprot ID:	P24928
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	6-phosphofructokinase, liver type
Reactions:	ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756]
Gene Name:	PFKL
Uniprot ID:	P17858
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	6-phosphofructokinase, muscle type
Reactions:	ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756]
Gene Name:	PFKM
Uniprot ID:	P08237
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyruvate kinase isozymes M1/M2
Reactions:	ATP + pyruvate = ADP + phosphoenolpyruvate [RN:R00200]
Gene Name:	PKM2
Uniprot ID:	P14618
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphatidate cytidylyltransferase 1
Reactions:	CTP + phosphatidate = diphosphate + CDP-diacylglycerol [RN:R01799]
Gene Name:	CDS1
Uniprot ID:	Q92903
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyruvate kinase isozymes R/L
Reactions:	ATP + pyruvate = ADP + phosphoenolpyruvate [RN:R00200]
Gene Name:	PKLR
Uniprot ID:	P30613
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Reactions:	CDP-diacylglycerol + myo-inositol = CMP + phosphatidyl-1D-myo-inositol [RN:R01802]
Gene Name:	CDIPT
Uniprot ID:	O14735
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transketolase-like protein 1
Reactions:	sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate [RN:R01641]
Gene Name:	TKTL1
Uniprot ID:	P51854
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transketolase
Reactions:	sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate [RN:R01641]
Gene Name:	TKT
Uniprot ID:	P29401
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NADP-dependent malic enzyme
Reactions:	(S)-malate + NADP+ = pyruvate + CO2 + NADPH [RN:R00216]
Gene Name:	ME1
Uniprot ID:	P48163
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NADP-dependent malic enzyme, mitochondrial
Reactions:	(S)-malate + NADP+ = pyruvate + CO2 + NADPH [RN:R00216]
Gene Name:	ME3
Uniprot ID:	Q16798
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NAD-dependent malic enzyme, mitochondrial
Reactions:	(S)-malate + NAD+ = pyruvate + CO2 + NADH [RN:R00214]
Gene Name:	ME2
Uniprot ID:	P23368
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inositol monophosphatase 1
Reactions:	myo-inositol phosphate + H2O = myo-inositol + phosphate [RN:R07343]
Gene Name:	IMPA1
Uniprot ID:	P29218
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cytosol aminopeptidase
Reactions:	Release of N-terminal proline from a peptide ALL_REAC (other) R00135 COFACTOR Manganese [CPD:C00034]
Gene Name:	LAP3
Uniprot ID:	P28838
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 4
Reactions:	a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329]
Gene Name:	ENTPD4
Uniprot ID:	Q9Y227
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 6
Reactions:	a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329]
Gene Name:	ENTPD6
Uniprot ID:	O75354
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 5
Reactions:	a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329]
Gene Name:	ENTPD5
Uniprot ID:	O75356
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylosuccinate synthetase isozyme 2
Reactions:	GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP [RN:R01135]
Gene Name:	ADSS
Uniprot ID:	P30520
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylosuccinate synthetase isozyme 1
Reactions:	GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP [RN:R01135]
Gene Name:	ADSSL1
Uniprot ID:	Q8N142
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoserine phosphatase
Reactions:	O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate [RN:R00582 R02853]
Gene Name:	PSPH
Uniprot ID:	P78330
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isocitrate dehydrogenase [NADP], mitochondrial
Reactions:	(1) isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+ (overall reaction) [RN:R00267] (2) (1a) isocitrate + NADP+ = oxalosuccinate + NADPH + H+ [RN:R01899] (3) (1b) oxalosuccinate = 2-oxoglutarate + CO2 [RN:R00268]
Gene Name:	IDH2
Uniprot ID:	P48735
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
Reactions:	isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH [RN:R00709]
Gene Name:	IDH3B
Uniprot ID:	O43837
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isocitrate dehydrogenase [NADP] cytoplasmic
Reactions:	(1) isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+ (overall reaction) [RN:R00267] (2) (1a) isocitrate + NADP+ = oxalosuccinate + NADPH + H+ [RN:R01899] (3) (1b) oxalosuccinate = 2-oxoglutarate + CO2 [RN:R00268]
Gene Name:	IDH1
Uniprot ID:	O75874
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
Reactions:	isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH [RN:R00709]
Gene Name:	IDH3A
Uniprot ID:	P50213
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
Reactions:	isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH [RN:R00709]
Gene Name:	IDH3G
Uniprot ID:	P51553
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Reactions:	5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate [RN:R01655]
Gene Name:	MTHFD2
Uniprot ID:	P13995
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 2
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY2
Uniprot ID:	Q08462
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein O-mannosyl-transferase 1
Reactions:	dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein [RN:R04072 R07620]
Gene Name:	POMT1
Uniprot ID:	Q9Y6A1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein O-mannosyl-transferase 2
Reactions:	dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein [RN:R04072 R07620]
Gene Name:	POMT2
Uniprot ID:	Q9UKY4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase beta
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLB
Uniprot ID:	P06746
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase eta
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLH
Uniprot ID:	Q9Y253
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase mu
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLM
Uniprot ID:	Q9NP87
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase kappa
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLK
Uniprot ID:	Q9UBT6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase subunit gamma-1
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLG
Uniprot ID:	P54098
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA polymerase iota
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	POLI
Uniprot ID:	Q9UNA4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
Reactions:	UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl- (11)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)- beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide [RN:R05631 R05962]
Gene Name:	B3GALNT1
Uniprot ID:	O75752
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyridoxal kinase
Reactions:	ATP + pyridoxal = ADP + pyridoxal 5'-phosphate [RN:R00174]
Gene Name:	PDXK
Uniprot ID:	O00764
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Riboflavin kinase
Reactions:	ATP + riboflavin = ADP + FMN [RN:R00549]
Gene Name:	RFK
Uniprot ID:	Q969G6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Guanylate cyclase soluble subunit beta-1
Reactions:	GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434]
Gene Name:	GUCY1B3
Uniprot ID:	Q02153
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Guanylate cyclase soluble subunit alpha-3
Reactions:	GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434]
Gene Name:	GUCY1A3
Uniprot ID:	Q02108
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inorganic pyrophosphatase
Reactions:	diphosphate + H2O = 2 phosphate [RN:R00004]
Gene Name:	PPA1
Uniprot ID:	Q15181
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Guanylate cyclase soluble subunit alpha-2
Reactions:	GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434]
Gene Name:	GUCY1A2
Uniprot ID:	P33402
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA nucleotidylexotransferase
Reactions:	deoxynucleoside triphosphate + DNAn = diphosphate + DNAn+1 [RN:R00379]
Gene Name:	DNTT
Uniprot ID:	P04053
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Guanylate cyclase soluble subunit beta-2
Reactions:	GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434]
Gene Name:	GUCY1B2
Uniprot ID:	O75343
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sphingosine kinase 1
Reactions:	ATP + sphinganine = ADP + sphinganine 1-phosphate [RN:R02976]
Gene Name:	SPHK1
Uniprot ID:	Q9NYA1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sphingosine kinase 2
Reactions:	ATP + sphinganine = ADP + sphinganine 1-phosphate [RN:R02976]
Gene Name:	SPHK2
Uniprot ID:	Q9NRA0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Beta-enolase
Reactions:	2-phospho-D-glycerate = phosphoenolpyruvate + H2O [RN:R00658]
Gene Name:	ENO3
Uniprot ID:	P13929
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Gamma-enolase
Reactions:	2-phospho-D-glycerate = phosphoenolpyruvate + H2O [RN:R00658]
Gene Name:	ENO2
Uniprot ID:	P09104
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Alpha-enolase
Reactions:	2-phospho-D-glycerate = phosphoenolpyruvate + H2O [RN:R00658]
Gene Name:	ENO1
Uniprot ID:	P06733
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sphingomyelin phosphodiesterase 2
Reactions:	sphingomyelin + H2O = N-acylsphingosine + choline phosphate [RN:R02541]
Gene Name:	SMPD2
Uniprot ID:	O60906
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Uridine diphosphate glucose pyrophosphatase
Reactions:	UDP-sugar + H2O = UMP + alpha-D-aldose 1-phosphate [RN:R03986]
Gene Name:	NUDT14
Uniprot ID:	O95848
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoglucomutase-1
Reactions:	alpha-D-glucose 1-phosphate = D-glucose 6-phosphate [RN:R08639]
Gene Name:	PGM1
Uniprot ID:	P36871
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inositol monophosphatase 2
Reactions:	myo-inositol phosphate + H2O = myo-inositol + phosphate [RN:R07343]
Gene Name:	IMPA2
Uniprot ID:	O14732
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Microtubule-associated serine/threonine-protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAST1
Uniprot ID:	Q9Y2H9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K1
Uniprot ID:	Q13233
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 12
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK12
Uniprot ID:	P53778
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP4K3
Uniprot ID:	Q8IVH8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K3
Uniprot ID:	Q99759
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Death-associated protein kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DAPK3
Uniprot ID:	O43293
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activin receptor type-2B
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVR2B
Uniprot ID:	Q13705
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Death-associated protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DAPK2
Uniprot ID:	Q9UIK4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Plasma membrane calcium-transporting ATPase 3
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2B3
Uniprot ID:	Q16720
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK4
Uniprot ID:	P51957
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase NLK
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NLK
Uniprot ID:	Q9UBE8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA2
Uniprot ID:	Q15349
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase haspin
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	GSG2
Uniprot ID:	Q8TF76
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK1
Uniprot ID:	Q96PY6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activin receptor type-1
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVR1
Uniprot ID:	Q04771
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 38
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK38
Uniprot ID:	Q15208
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP4K1
Uniprot ID:	Q92918
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK1
Uniprot ID:	P28482
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cell division protein kinase 8
Reactions:	ATP + [DNA-directed RNA polymerase] = ADP + phospho-[DNA-directed RNA polymerase] [RN:R04358]
Gene Name:	CDK8
Uniprot ID:	P49336
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase ICK
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	ICK
Uniprot ID:	Q9UPZ9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase SIK1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SIK1
Uniprot ID:	P57059
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit beta-3
Reactions:
Gene Name:	ATP1B3
Uniprot ID:	P54709
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Plasma membrane calcium-transporting ATPase 1
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2B1
Uniprot ID:	P20020
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 7
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK7
Uniprot ID:	Q13164
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity testis-specific protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TESK2
Uniprot ID:	Q96S53
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bone morphogenetic protein receptor type-1A
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	BMPR1A
Uniprot ID:	P36894
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Wee1-like protein kinase
Reactions:	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate [RN:R02584]
Gene Name:	WEE1
Uniprot ID:	P30291
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase PINK1, mitochondrial
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PINK1
Uniprot ID:	Q9BXM7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase receptor R3
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVRL1
Uniprot ID:	P37023
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit beta-2
Reactions:
Gene Name:	ATP1B2
Uniprot ID:	P14415
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bone morphogenetic protein receptor type-1B
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	BMPR1B
Uniprot ID:	O00238
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Plasma membrane calcium-transporting ATPase 2
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2B2
Uniprot ID:	Q01814
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA4
Uniprot ID:	O75676
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit beta-1
Reactions:
Gene Name:	ATP1B1
Uniprot ID:	P05026
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	MAP kinase-interacting serine/threonine-protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MKNK2
Uniprot ID:	Q9HBH9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	TGF-beta receptor type-2
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	TGFBR2
Uniprot ID:	P37173
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 38-like
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK38L
Uniprot ID:	Q9Y2H1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transient receptor potential cation channel subfamily M member 6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TRPM6
Uniprot ID:	Q9BX84
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Chk2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CHEK2
Uniprot ID:	O96017
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Calcium-transporting ATPase type 2C member 2
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2C2
Uniprot ID:	O75185
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta
Reactions:	ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [RN:R05795]
Gene Name:	PIK3C2B
Uniprot ID:	O00750
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2A3
Uniprot ID:	Q93084
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Death-associated protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DAPK1
Uniprot ID:	P53355
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK3
Uniprot ID:	P27361
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK6
Uniprot ID:	Q9HC98
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NUAK family SNF1-like kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NUAK1
Uniprot ID:	O60285
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	BR serine/threonine-protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	BRSK2
Uniprot ID:	Q8IWQ3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MARK1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MARK1
Uniprot ID:	Q9P0L2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK3
Uniprot ID:	P51956
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA1
Uniprot ID:	Q15418
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	TGF-beta receptor type-1
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	TGFBR1
Uniprot ID:	P36897
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Testis-specific serine/threonine-protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TSSK2
Uniprot ID:	Q96PF2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek9
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK9
Uniprot ID:	Q8TD19
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 9
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK9
Uniprot ID:	P45984
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein ATP1B4
Reactions:
Gene Name:	ATP1B4
Uniprot ID:	Q9UN42
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity tyrosine-phosphorylation-regulated kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DYRK2
Uniprot ID:	Q92630
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase WNK4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	WNK4
Uniprot ID:	Q96J92
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 13
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK13
Uniprot ID:	O15264
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Tyrosine-protein kinase ABL2
Reactions:	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate [RN:R02584]
Gene Name:	ABL2
Uniprot ID:	P42684
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 7
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K7
Uniprot ID:	O43318
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 11
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK11
Uniprot ID:	Q15759
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK2
Uniprot ID:	P51955
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Plasma membrane calcium-transporting ATPase 4
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2B4
Uniprot ID:	P23634
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activated CDC42 kinase 1
Reactions:	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate [RN:R02584]
Gene Name:	TNK2
Uniprot ID:	Q07912
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Testis-specific serine/threonine-protein kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TSSK4
Uniprot ID:	Q6SA08
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 10
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K10
Uniprot ID:	Q02779
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA6
Uniprot ID:	Q9UK32
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cell division protein kinase 15
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDK15
Uniprot ID:	Q96Q40
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2A1
Uniprot ID:	O14983
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 12
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K12
Uniprot ID:	Q12852
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit alpha-1
Reactions:	ATP + H2O + Na+in + K+out = ADP + phosphate + Na+out + K+in [RN:R00086]
Gene Name:	ATP1A1
Uniprot ID:	P05023
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP4K2
Uniprot ID:	Q12851
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Calcium-transporting ATPase type 2C member 1
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2C1
Uniprot ID:	P98194
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase PAK 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PAK3
Uniprot ID:	O75914
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Tyrosine-protein kinase ABL1
Reactions:	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate [RN:R02584]
Gene Name:	ABL1
Uniprot ID:	P00519
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ceramide kinase
Reactions:	ATP + ceramide = ADP + ceramide 1-phosphate [RN:R01495]
Gene Name:	CERK
Uniprot ID:	Q8TCT0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase LATS2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	LATS2
Uniprot ID:	Q9NRM7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activin receptor type-1B
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVR1B
Uniprot ID:	P36896
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5-formyltetrahydrofolate cyclo-ligase
Reactions:	ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate [RN:R02301]
Gene Name:	MTHFS
Uniprot ID:	P49914
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Testis-specific serine/threonine-protein kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TSSK3
Uniprot ID:	Q96PN8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	cAMP-dependent protein kinase catalytic subunit beta
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PRKACB
Uniprot ID:	P22694
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit alpha-3
Reactions:	ATP + H2O + Na+in + K+out = ADP + phosphate + Na+out + K+in [RN:R00086]
Gene Name:	ATP1A3
Uniprot ID:	P13637
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Myosin light chain kinase, smooth muscle
Reactions:	ATP + [myosin light chain] = ADP + [myosin light chain] phosphate [RN:R03150]
Gene Name:	MYLK
Uniprot ID:	Q15746
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 12
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	AURKB
Uniprot ID:	Q96GD4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Vesicle-fusing ATPase
Reactions:	ATP + H2O = ADP + phosphate [RN:R00086]
Gene Name:	NSF
Uniprot ID:	P46459
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase kinase 5
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP4K5
Uniprot ID:	Q9Y4K4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek7
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK7
Uniprot ID:	Q8TDX7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 25
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK25
Uniprot ID:	O00506
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase tousled-like 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TLK2
Uniprot ID:	Q86UE8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA3
Uniprot ID:	P51812
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K4
Uniprot ID:	Q9Y6R4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Microtubule-associated serine/threonine-protein kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAST2
Uniprot ID:	Q6P0Q8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK3
Uniprot ID:	Q13188
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bone morphogenetic protein receptor type-2
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	BMPR2
Uniprot ID:	Q13873
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ectonucleoside triphosphate diphosphohydrolase 2
Reactions:	--- []
Gene Name:	ENTPD2
Uniprot ID:	Q9Y5L3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Interleukin-1 receptor-associated kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	IRAK4
Uniprot ID:	Q9NWZ3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase tousled-like 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TLK1
Uniprot ID:	Q9UKI8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Reactions:	ATP + H2O + Ca2+cis = ADP + phosphate + Ca2+trans [RN:R00086]
Gene Name:	ATP2A2
Uniprot ID:	P16615
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	BR serine/threonine-protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	BRSK1
Uniprot ID:	Q8TDC3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	MAP kinase-interacting serine/threonine-protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MKNK1
Uniprot ID:	Q9BUB5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK4
Uniprot ID:	P31152
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK4
Uniprot ID:	Q13043
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribosomal protein S6 kinase alpha-5
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	RPS6KA5
Uniprot ID:	O75582
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek8
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK8
Uniprot ID:	Q86SG6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP4K4
Uniprot ID:	O95819
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase LATS1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	LATS1
Uniprot ID:	O95835
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase WNK2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	WNK2
Uniprot ID:	Q9Y3S1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MARK2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MARK2
Uniprot ID:	Q7KZI7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 14
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK14
Uniprot ID:	Q16539
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activin receptor type-2A
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVR2A
Uniprot ID:	P27037
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transient receptor potential cation channel subfamily M member 7
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TRPM7
Uniprot ID:	Q96QT4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cell division protein kinase 11B
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDK11B
Uniprot ID:	P21127
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Anti-Muellerian hormone type-2 receptor
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	AMHR2
Uniprot ID:	Q16671
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Testis-specific serine/threonine-protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TSSK1B
Uniprot ID:	Q9BXA7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK6
Uniprot ID:	Q16659
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 11
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK11
Uniprot ID:	Q15831
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 10
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK10
Uniprot ID:	P53779
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit alpha-2
Reactions:	ATP + H2O + Na+in + K+out = ADP + phosphate + Na+out + K+in [RN:R00086]
Gene Name:	ATP1A2
Uniprot ID:	P50993
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase 8
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAPK8
Uniprot ID:	P45983
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isopentenyl-diphosphate Delta-isomerase 2
Reactions:	isopentenyl diphosphate = dimethylallyl diphosphate [RN:R01123]
Gene Name:	IDI2
Uniprot ID:	Q9BXS1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Isopentenyl-diphosphate Delta-isomerase 1
Reactions:	isopentenyl diphosphate = dimethylallyl diphosphate [RN:R01123]
Gene Name:	IDI1
Uniprot ID:	Q13907
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Reactions:	phosphatidylinositol 3,4,5-trisphosphate + H2O = phosphatidylinositol 4,5-bisphosphate + phosphate [RN:R04513]
Gene Name:	PTEN
Uniprot ID:	P60484
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoacetylglucosamine mutase
Reactions:	N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate [RN:R08193]
Gene Name:	PGM3
Uniprot ID:	O95394
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit zeta-1
Reactions:
Gene Name:	GRIN1
Uniprot ID:	Q05586
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit 3B
Reactions:
Gene Name:	GRIN3B
Uniprot ID:	O60391
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit epsilon-1
Reactions:
Gene Name:	GRIN2A
Uniprot ID:	Q12879
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit epsilon-3
Reactions:
Gene Name:	GRIN2C
Uniprot ID:	Q14957
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit epsilon-2
Reactions:
Gene Name:	GRIN2B
Uniprot ID:	Q13224
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit epsilon-4
Reactions:
Gene Name:	GRIN2D
Uniprot ID:	O15399
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Hyaluronan synthase 1
Reactions:	(1) UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)- [nascent hyaluronan] = UDP + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N- acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] [RN:R05327 R06068] (2) UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)- [nascent hyaluronan] = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta- D-glucuronosyl-(1->3)-[nascent hyaluronan]
Gene Name:	HAS1
Uniprot ID:	Q92839
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Hyaluronan synthase 3
Reactions:	(1) UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)- [nascent hyaluronan] = UDP + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N- acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] [RN:R05327 R06068] (2) UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)- [nascent hyaluronan] = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta- D-glucuronosyl-(1->3)-[nascent hyaluronan]
Gene Name:	HAS3
Uniprot ID:	O00219
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Elastin
Reactions:
Gene Name:	ELN
Uniprot ID:	P15502
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Epoxide hydrolase 2
Reactions:	an epoxide + H2O = a glycol [RN:R02822]
Gene Name:	EPHX2
Uniprot ID:	P34913
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein kinase C theta type
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PRKCQ
Uniprot ID:	Q04759
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Hyaluronan synthase 2
Reactions:	(1) UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)- [nascent hyaluronan] = UDP + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N- acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] [RN:R05327 R06068] (2) UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)- [nascent hyaluronan] = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta- D-glucuronosyl-(1->3)-[nascent hyaluronan]
Gene Name:	HAS2
Uniprot ID:	Q92819
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5'-AMP-activated protein kinase catalytic subunit alpha-1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PRKAA1
Uniprot ID:	Q13131
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5'-AMP-activated protein kinase catalytic subunit alpha-2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PRKAA2
Uniprot ID:	P54646
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transforming protein RhoA
Reactions:
Gene Name:	RHOA
Uniprot ID:	P61586
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cyclic AMP-responsive element-binding protein 1
Reactions:
Gene Name:	CREB1
Uniprot ID:	P16220
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inward rectifier potassium channel 2
Reactions:
Gene Name:	KCNJ2
Uniprot ID:	P63252
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pro-epidermal growth factor
Reactions:
Gene Name:	EGF
Uniprot ID:	P01133
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPP2CA
Uniprot ID:	P67775
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Poly(ADP-ribose) glycohydrolase ARH3
Reactions:	hydrolyses poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose
Gene Name:	ADPRHL2
Uniprot ID:	Q9NX46
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 1
Reactions:
Gene Name:	KCNJ1
Uniprot ID:	P48048
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribonuclease H2 subunit A
Reactions:	Endonucleolytic cleavage to 5'-phosphomonoester
Gene Name:	RNASEH2A
Uniprot ID:	O75792
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Calsenilin
Reactions:
Gene Name:	KCNIP3
Uniprot ID:	Q9Y2W7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Heparanase
Reactions:
Gene Name:	HPSE
Uniprot ID:	Q9Y251
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cholinephosphotransferase 1
Reactions:	CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine [RN:R01321]
Gene Name:	CHPT1
Uniprot ID:	Q8WUD6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Gephyrin
Reactions:
Gene Name:	GPHN
Uniprot ID:	Q9NQX3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 11
Reactions:
Gene Name:	KCNJ11
Uniprot ID:	Q14654
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoethanolamine/phosphocholine phosphatase
Reactions:	(1) O-phosphoethanolamine + H2O = ethanolamine + phosphate [RN:R06870] (2) phosphocholine + H2O = choline + phosphate [RN:R06871]
Gene Name:	PHOSPHO1
Uniprot ID:	Q8TCT1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha
Reactions:	ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [RN:R05795]
Gene Name:	PIK3C2A
Uniprot ID:	O00443
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit alpha-4
Reactions:	ATP + H2O + Na+in + K+out = ADP + phosphate + Na+out + K+in [RN:R00086]
Gene Name:	ATP1A4
Uniprot ID:	Q13733
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cytosolic 5'-nucleotidase 3
Reactions:	a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297]
Gene Name:	NT5C3
Uniprot ID:	Q9H0P0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Choline/ethanolaminephosphotransferase 1
Reactions:	CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine [RN:R01321]
Gene Name:	CEPT1
Uniprot ID:	Q9Y6K0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
Reactions:	CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate [RN:R01801]
Gene Name:	PGS1
Uniprot ID:	Q32NB8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoglucomutase-2
Reactions:	alpha-D-ribose 1-phosphate = D-ribose 5-phosphate [RN:R01057]
Gene Name:	PGM2
Uniprot ID:	Q96G03
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyridoxal phosphate phosphatase
Reactions:	pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate [RN:R00173]
Gene Name:	PDXP
Uniprot ID:	Q96GD0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Adenylate cyclase type 10
Reactions:	ATP = 3',5'-cyclic AMP + diphosphate [RN:R00089]
Gene Name:	ADCY10
Uniprot ID:	Q96PN6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM1, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM1
Uniprot ID:	Q08AH1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inorganic pyrophosphatase 2, mitochondrial
Reactions:	diphosphate + H2O = 2 phosphate [RN:R00004]
Gene Name:	PPA2
Uniprot ID:	Q9H2U2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Citrate lyase subunit beta-like protein, mitochondrial
Reactions:
Gene Name:	CLYBL
Uniprot ID:	Q8N0X4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sphingomyelin phosphodiesterase 3
Reactions:	sphingomyelin + H2O = N-acylsphingosine + choline phosphate [RN:R02541]
Gene Name:	SMPD3
Uniprot ID:	Q9NY59
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Reactions:	UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP + glycoprotein D-galactosyl-(1->3)-N-acetyl-D-galactosamine [RN:R05908]
Gene Name:	C1GALT1
Uniprot ID:	Q9NS00
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transketolase-like protein 2
Reactions:	sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate [RN:R01641]
Gene Name:	TKTL2
Uniprot ID:	Q9H0I9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Beta-1,4-galactosyltransferase 6
Reactions:
Gene Name:	B4GALT6
Uniprot ID:	Q9UBX8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2
Reactions:	5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate [RN:R01655]
Gene Name:	MTHFD2L
Uniprot ID:	Q9H903
Protein Sequence:	FASTA

Name:	Ethanolaminephosphotransferase 1
Reactions:	CDP-ethanolamine + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylethanolamine [RN:R02057]
Gene Name:	EPT1
Uniprot ID:	Q9C0D9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	N-acylneuraminate-9-phosphatase
Reactions:	N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate [RN:R02597]
Gene Name:	NANP
Uniprot ID:	Q8TBE9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acetolactate synthase-like protein
Reactions:
Gene Name:	ILVBL
Uniprot ID:	A1L0T0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glycerophosphodiester phosphodiesterase 1
Reactions:	1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate [RN:R01193]
Gene Name:	GDE1
Uniprot ID:	Q9NZC3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inositol-tetrakisphosphate 1-kinase
Reactions:	(1) ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate [RN:R03428] (2) ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate [RN:R03429]
Gene Name:	ITPK1
Uniprot ID:	Q13572
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Peroxisomal NADH pyrophosphatase NUDT12
Reactions:	NAD+ + H2O = AMP + NMN [RN:R00103]
Gene Name:	NUDT12
Uniprot ID:	Q9BQG2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	FAD synthase
Reactions:	ATP + FMN = diphosphate + FAD [RN:R00161]
Gene Name:	FLAD1
Uniprot ID:	Q8NFF5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Anthrax toxin receptor 2
Reactions:
Gene Name:	ANTXR2
Uniprot ID:	P58335
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sodium/potassium-transporting ATPase subunit gamma
Reactions:
Gene Name:	FXYD2
Uniprot ID:	P54710
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cell adhesion molecule 4
Reactions:
Gene Name:	CADM4
Uniprot ID:	Q8NFZ8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Claudin-16
Reactions:
Gene Name:	CLDN16
Uniprot ID:	Q9Y5I7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Claudin-19
Reactions:
Gene Name:	CLDN19
Uniprot ID:	Q8N6F1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Deoxyribonuclease gamma
Reactions:
Gene Name:	DNASE1L3
Uniprot ID:	Q13609
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Fumarylacetoacetate hydrolase domain-containing protein 2A
Reactions:
Gene Name:	FAHD2A
Uniprot ID:	Q96GK7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Fumarylacetoacetate hydrolase domain-containing protein 2B
Reactions:
Gene Name:	FAHD2B
Uniprot ID:	Q6P2I3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Fumarylacetoacetate hydrolase domain-containing protein 1
Reactions:
Gene Name:	FAHD1
Uniprot ID:	Q6P587
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Integrin beta-7
Reactions:
Gene Name:	ITGB7
Uniprot ID:	P26010
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Magnesium-dependent phosphatase 1
Reactions:	protein tyrosine phosphate + H2O = protein tyrosine + phosphate [RN:R02585]
Gene Name:	MDP1
Uniprot ID:	Q86V88
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitochondrial intermediate peptidase
Reactions:	Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion
Gene Name:	MIPEP
Uniprot ID:	Q99797
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Glutamate [NMDA] receptor subunit 3A
Reactions:
Gene Name:	GRIN3A
Uniprot ID:	Q8TCU5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NADPH oxidase 5
Reactions:
Gene Name:	NOX5
Uniprot ID:	Q96PH1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein phosphatase with EF-hands 1
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPEF1
Uniprot ID:	O14829
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ryanodine receptor 1
Reactions:
Gene Name:	RYR1
Uniprot ID:	P21817
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ryanodine receptor 2
Reactions:
Gene Name:	RYR2
Uniprot ID:	Q92736
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ryanodine receptor 3
Reactions:
Gene Name:	RYR3
Uniprot ID:	Q15413
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA topoisomerase I, mitochondrial
Reactions:	ATP-independent breakage of single-stranded DNA, followed by passage and rejoining INHIBITOR Camptothecin [CPD:C01897]
Gene Name:	TOP1MT
Uniprot ID:	Q969P6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Tau-tubulin kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TTBK1
Uniprot ID:	Q5TCY1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein prune homolog
Reactions:	diphosphate + H2O = 2 phosphate [RN:R00004]
Gene Name:	PRUNE
Uniprot ID:	Q86TP1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Chloride channel protein ClC-Kb
Reactions:
Gene Name:	CLCNKB
Uniprot ID:	P51801
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase OSR1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	OXSR1
Uniprot ID:	O95747
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase WNK1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	WNK1
Uniprot ID:	Q9H4A3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	U8 snoRNA-decapping enzyme
Reactions:
Gene Name:	NUDT16
Uniprot ID:	Q96DE0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
Reactions:	[pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate [RN:R03450]
Gene Name:	PDP2
Uniprot ID:	Q9P2J9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM6, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM6
Uniprot ID:	Q6P461
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Exocyst complex component 2
Reactions:
Gene Name:	EXOC2
Uniprot ID:	Q96KP1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	GTPase IMAP family member 4
Reactions:
Gene Name:	GIMAP4
Uniprot ID:	Q9NUV9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Kalirin
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	KALRN
Uniprot ID:	O60229
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Leucine-rich repeat serine/threonine-protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	LRRK1
Uniprot ID:	Q38SD2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MRCK alpha
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDC42BPA
Uniprot ID:	Q5VT25
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MRCK beta
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDC42BPB
Uniprot ID:	Q9Y5S2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MRCK gamma
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDC42BPG
Uniprot ID:	Q6DT37
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase PAK 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	PAK1
Uniprot ID:	Q13153
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Secretion-regulating guanine nucleotide exchange factor
Reactions:
Gene Name:	SERGEF
Uniprot ID:	Q9UGK8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM2A, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM2A
Uniprot ID:	Q08AH3
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM2B, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM2B
Uniprot ID:	Q68CK6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM3, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM3
Uniprot ID:	Q53FZ2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM5, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM5
Uniprot ID:	Q6NUN0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Activin receptor type-1C
Reactions:	ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Gene Name:	ACVR1C
Uniprot ID:	Q8NER5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acylglycerol kinase, mitochondrial
Reactions:	ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240]
Gene Name:	AGK
Uniprot ID:	Q53H12
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Bloom syndrome protein
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	BLM
Uniprot ID:	P54132
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Cell division protein kinase 11A
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CDK11A
Uniprot ID:	Q9UQ88
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
Reactions:	Hydrolysis of proteins to small peptides in the presence of ATP and Mg2+. alpha-Casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolysed (such as succinyl-Leu-Tyr!NHMec and Leu-Tyr-Leu!Tyr-Trp, in which cleavage of the -Tyr!Leu- and -Tyr!Trp bonds also occurs)
Gene Name:	CLPP
Uniprot ID:	Q16740
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	CCR4-NOT transcription complex subunit 6
Reactions:
Gene Name:	CNOT6
Uniprot ID:	Q9ULM6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Peripheral plasma membrane protein CASK
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	CASK
Uniprot ID:	O14936
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	mRNA-decapping enzyme 2
Reactions:
Gene Name:	DCP2
Uniprot ID:	Q8IU60
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Myotonin-protein kinase
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DMPK
Uniprot ID:	Q09013
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity tyrosine-phosphorylation-regulated kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DYRK3
Uniprot ID:	O43781
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity tyrosine-phosphorylation-regulated kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	DYRK4
Uniprot ID:	Q9NR20
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Crossover junction endonuclease EME1
Reactions:
Gene Name:	EME1
Uniprot ID:	Q96AY2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitochondrial enolase superfamily member 1
Reactions:
Gene Name:	ENOSF1
Uniprot ID:	Q7L5Y1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Enolase-phosphatase E1
Reactions:	(1) 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate (overall reaction) [RN:R07395] (2) (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate (probably spontaneous) [RN:R07393] (3) (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate [RN:R07394]
Gene Name:	ENOPH1
Uniprot ID:	Q9UHY7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	TFIIH basal transcription factor complex helicase XPD subunit
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	ERCC2
Uniprot ID:	P18074
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase/endoribonuclease IRE1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	ERN1
Uniprot ID:	O75460
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase/endoribonuclease IRE2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	ERN2
Uniprot ID:	Q76MJ5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Eyes absent homolog 1
Reactions:	protein tyrosine phosphate + H2O = protein tyrosine + phosphate [RN:R02585]
Gene Name:	EYA1
Uniprot ID:	Q99502
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Eyes absent homolog 2
Reactions:	protein tyrosine phosphate + H2O = protein tyrosine + phosphate [RN:R02585]
Gene Name:	EYA2
Uniprot ID:	O00167
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Eyes absent homolog 3
Reactions:	protein tyrosine phosphate + H2O = protein tyrosine + phosphate [RN:R02585]
Gene Name:	EYA3
Uniprot ID:	Q99504
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Eyes absent homolog 4
Reactions:	protein tyrosine phosphate + H2O = protein tyrosine + phosphate [RN:R02585]
Gene Name:	EYA4
Uniprot ID:	O95677
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Fidgetin-like protein 1
Reactions:
Gene Name:	FIGNL1
Uniprot ID:	Q6PIW4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Forkhead box protein K2
Reactions:
Gene Name:	FOXK2
Uniprot ID:	Q01167
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ras GTPase-activating protein-binding protein 1
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	G3BP1
Uniprot ID:	Q13283
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Galactose-3-O-sulfotransferase 3
Reactions:
Gene Name:	GAL3ST3
Uniprot ID:	Q96A11
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Flap endonuclease GEN homolog 1
Reactions:
Gene Name:	GEN1
Uniprot ID:	Q17RS7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	2-hydroxyacyl-CoA lyase 1
Reactions:
Gene Name:	HACL1
Uniprot ID:	Q9UJ83
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA helicase B
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	HELB
Uniprot ID:	Q8NG08
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Integrin-linked kinase-associated serine/threonine phosphatase 2C
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	ILKAP
Uniprot ID:	Q9H0C8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inositol monophosphatase 3
Reactions:	myo-inositol phosphate + H2O = myo-inositol + phosphate [RN:R07343]
Gene Name:	IMPAD1
Uniprot ID:	Q9NX62
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Interleukin-1 receptor-associated kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	IRAK1
Uniprot ID:	P51617
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Interleukin-1 receptor-associated kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	IRAK3
Uniprot ID:	Q9Y616
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 10
Reactions:
Gene Name:	KCNJ10
Uniprot ID:	P78508
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 12
Reactions:
Gene Name:	KCNJ12
Uniprot ID:	Q14500
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inward rectifier potassium channel 13
Reactions:
Gene Name:	KCNJ13
Uniprot ID:	O60928
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 14
Reactions:
Gene Name:	KCNJ14
Uniprot ID:	Q9UNX9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 15
Reactions:
Gene Name:	KCNJ15
Uniprot ID:	Q99712
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inward rectifier potassium channel 16
Reactions:
Gene Name:	KCNJ16
Uniprot ID:	Q9NPI9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	G protein-activated inward rectifier potassium channel 1
Reactions:
Gene Name:	KCNJ3
Uniprot ID:	P48549
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Inward rectifier potassium channel 4
Reactions:
Gene Name:	KCNJ4
Uniprot ID:	P48050
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	G protein-activated inward rectifier potassium channel 4
Reactions:
Gene Name:	KCNJ5
Uniprot ID:	P48544
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	G protein-activated inward rectifier potassium channel 2
Reactions:
Gene Name:	KCNJ6
Uniprot ID:	P48051
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-sensitive inward rectifier potassium channel 8
Reactions:
Gene Name:	KCNJ8
Uniprot ID:	Q15842
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	G protein-activated inward rectifier potassium channel 3
Reactions:
Gene Name:	KCNJ9
Uniprot ID:	Q92806
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 11
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K11
Uniprot ID:	Q16584
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 13
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K13
Uniprot ID:	O43283
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 15
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K15
Uniprot ID:	Q6ZN16
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K2
Uniprot ID:	Q9Y2U5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 5
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K5
Uniprot ID:	Q99683
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K6
Uniprot ID:	O95382
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 8
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K8
Uniprot ID:	P41279
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase 9
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP3K9
Uniprot ID:	P80192
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase MLK4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MLK4
Uniprot ID:	Q5TCX8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Microtubule-associated serine/threonine-protein kinase 3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAST3
Uniprot ID:	O60307
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Microtubule-associated serine/threonine-protein kinase 4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAST4
Uniprot ID:	O15021
Protein Sequence:	FASTA

Name:	Misshapen-like kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MINK1
Uniprot ID:	Q8N4C8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Mitogen-activated protein kinase kinase kinase MLT
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MLTK
Uniprot ID:	Q9NYL2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity mitogen-activated protein kinase kinase 5
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP2K5
Uniprot ID:	Q13163
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity mitogen-activated protein kinase kinase 7
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MAP2K7
Uniprot ID:	O14733
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Magnesium transporter MRS2 homolog, mitochondrial
Reactions:
Gene Name:	MRS2
Uniprot ID:	Q9HD23
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase MST4
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	MST4
Uniprot ID:	Q9P289
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Crossover junction endonuclease MUS81
Reactions:
Gene Name:	MUS81
Uniprot ID:	Q96NY9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Putative myosin light chain kinase 3
Reactions:	ATP + [myosin light chain] = ADP + [myosin light chain] phosphate [RN:R03150]
Gene Name:	MYLK3
Uniprot ID:	Q32MK0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Putative nucleoside diphosphate kinase
Reactions:	ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331]
Gene Name:	NME2P1
Uniprot ID:	O60361
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek10
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK10
Uniprot ID:	Q6ZWH5
Protein Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek11
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK11
Uniprot ID:	Q8NG66
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase Nek5
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NEK5
Uniprot ID:	Q6P3R8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase NIM1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NIM1
Uniprot ID:	Q8IY84
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sphingomyelin phosphodiesterase 4
Reactions:	sphingomyelin + H2O = N-acylsphingosine + choline phosphate [RN:R02541]
Gene Name:	SMPD4
Uniprot ID:	Q9NXE4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	5'-nucleotidase domain-containing protein 3
Reactions:
Gene Name:	NT5DC3
Uniprot ID:	Q86UY8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	NUAK family SNF1-like kinase 2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	NUAK2
Uniprot ID:	Q9H093
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Endonuclease G, mitochondrial
Reactions:
Gene Name:	ENDOG
Uniprot ID:	Q14249
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Reactions:	diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate [RN:R05777]
Gene Name:	NUDT10
Uniprot ID:	Q8NFP7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Diphosphoinositol polyphosphate phosphohydrolase 3-beta
Reactions:	diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate [RN:R05777]
Gene Name:	NUDT11
Uniprot ID:	Q96G61
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15
Reactions:
Gene Name:	NUDT15
Uniprot ID:	Q9NV35
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate-linked moiety X motif 17
Reactions:
Gene Name:	NUDT17
Uniprot ID:	P0C025
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate-linked moiety X motif 18
Reactions:
Gene Name:	NUDT18
Uniprot ID:	Q6ZVK8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate-linked moiety X motif 19, mitochondrial
Reactions:
Gene Name:	NUDT19
Uniprot ID:	A8MXV4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Diphosphoinositol polyphosphate phosphohydrolase 1
Reactions:	diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate [RN:R05777]
Gene Name:	NUDT3
Uniprot ID:	O95989
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Diphosphoinositol polyphosphate phosphohydrolase 2
Reactions:	diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate [RN:R05777]
Gene Name:	NUDT4
Uniprot ID:	Q9NZJ9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Peroxisomal coenzyme A diphosphatase NUDT7
Reactions:
Gene Name:	NUDT7
Uniprot ID:	P0C024
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial
Reactions:
Gene Name:	NUDT8
Uniprot ID:	Q8WV74
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Obscurin
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	OBSCN
Uniprot ID:	Q5VST9
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
Reactions:	[pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate [RN:R03450]
Gene Name:	PDP1
Uniprot ID:	Q9P0J1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial
Reactions:
Gene Name:	PDPR
Uniprot ID:	Q8NCN5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Phosphoglucomutase-like protein 5
Reactions:
Gene Name:	PGM5
Uniprot ID:	Q15124
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Pyridoxal phosphate phosphatase PHOSPHO2
Reactions:	pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate [RN:R00173]
Gene Name:	PHOSPHO2
Uniprot ID:	Q8TCD6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Nuclear inhibitor of protein phosphatase 1
Reactions:
Gene Name:	PPP1R8
Uniprot ID:	Q12972
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1A
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1A
Uniprot ID:	P35813
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1B
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1B
Uniprot ID:	O75688
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1D
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1D
Uniprot ID:	O15297
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1E
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1E
Uniprot ID:	Q8WY54
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1F
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1F
Uniprot ID:	P49593
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1G
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1G
Uniprot ID:	O15355
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1K, mitochondrial
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1K
Uniprot ID:	Q8N3J5
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1L
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1L
Uniprot ID:	Q5SGD2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase 1M
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPM1M
Uniprot ID:	Q96MI6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Protein phosphatase PTC7 homolog
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	PPTC7
Uniprot ID:	Q8NI37
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	L-seryl-tRNA(Sec) kinase
Reactions:	ATP + L-seryl-tRNASec = ADP + O-phospho-L-seryl-tRNASec [RN:R08223]
Gene Name:	PSTK
Uniprot ID:	Q8IV42
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase SIK3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SIK3
Uniprot ID:	Q9Y2K2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	V(D)J recombination-activating protein 1
Reactions:
Gene Name:	RAG1
Uniprot ID:	P15918
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-dependent DNA helicase Q1
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	RECQL
Uniprot ID:	P46063
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Rho-related GTP-binding protein RhoV
Reactions:
Gene Name:	RHOV
Uniprot ID:	Q96L33
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	2-5A-dependent ribonuclease
Reactions:
Gene Name:	RNASEL
Uniprot ID:	Q05823
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ribonuclease H1
Reactions:	Endonucleolytic cleavage to 5'-phosphomonoester
Gene Name:	RNASEH1
Uniprot ID:	O60930
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Solute carrier family 41 member 1
Reactions:
Gene Name:	SLC41A1
Uniprot ID:	Q8IVJ1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Solute carrier family 41 member 2
Reactions:
Gene Name:	SLC41A2
Uniprot ID:	Q96JW4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase SIK2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SIK2
Uniprot ID:	Q9H0K1
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	SNF-related serine/threonine-protein kinase
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SNRK
Uniprot ID:	Q9NRH2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase SRPK1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SRPK1
Uniprot ID:	Q96SB4
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase SRPK2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	SRPK2
Uniprot ID:	P78362
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Sulfiredoxin-1
Reactions:	peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R
Gene Name:	SRXN1
Uniprot ID:	Q9BYN0
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 32A
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK32A
Uniprot ID:	Q8WU08
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 32B
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK32B
Uniprot ID:	Q9NY57
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 32C
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK32C
Uniprot ID:	Q86UX6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase 36
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	STK36
Uniprot ID:	Q9NRP7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	ATP-dependent RNA helicase SUPV3L1, mitochondrial
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	SUPV3L1
Uniprot ID:	Q8IYB8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Transcription initiation factor TFIID subunit 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TAF1
Uniprot ID:	P21675
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase TAO2
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TAOK2
Uniprot ID:	Q9UL54
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Dual specificity testis-specific protein kinase 1
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TESK1
Uniprot ID:	Q15569
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	3'-5' exoribonuclease 1
Reactions:
Gene Name:	ERI1
Uniprot ID:	Q8IV48
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Titin
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TTN
Uniprot ID:	Q8WZ42
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase TNNI3K
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TNNI3K
Uniprot ID:	Q59H18
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Three prime repair exonuclease 1
Reactions:	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Gene Name:	TREX1
Uniprot ID:	Q9NSU2
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Three prime repair exonuclease 2
Reactions:	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Gene Name:	TREX2
Uniprot ID:	Q9BQ50
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	tRNA-nucleotidyltransferase 1, mitochondrial
Reactions:	ATP + tRNAn = diphosphate + tRNAn+1 [RN:R07284]
Gene Name:	TRNT1
Uniprot ID:	Q96Q11
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Testis-specific serine/threonine-protein kinase 6
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	TSSK6
Uniprot ID:	Q9BXA6
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Tubulin--tyrosine ligase
Reactions:	ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate [RN:R04730]
Gene Name:	TTL
Uniprot ID:	Q8NG68
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Ubiquitin-like domain-containing CTD phosphatase 1
Reactions:	a phosphoprotein + H2O = a protein + phosphate [RN:R00164]
Gene Name:	UBLCP1
Uniprot ID:	Q8WVY7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Serine/threonine-protein kinase WNK3
Reactions:	ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Gene Name:	WNK3
Uniprot ID:	Q9BYP7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Werner syndrome ATP-dependent helicase
Reactions:	ATP + H2O = ADP + phosphate
Gene Name:	WRN
Uniprot ID:	Q14191
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA repair endonuclease XPF
Reactions:
Gene Name:	ERCC4
Uniprot ID:	Q92889
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Rho-related GTP-binding protein RhoU
Reactions:
Gene Name:	RHOU
Uniprot ID:	Q7L0Q8
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	Acyl-coenzyme A synthetase ACSM4, mitochondrial
Reactions:	ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389]
Gene Name:	ACSM4
Uniprot ID:	P0C7M7
Protein Sequence:	FASTA
Gene Sequence:	FASTA

Name:	DNA-(apurinic or apyrimidinic site) lyase
Reactions:	The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Gene Name:	APEX1
Uniprot ID:	P27695
Protein Sequence:	FASTA
Gene Sequence:	FASTA