Record Information
Version3.6
Creation Date2005-11-16 15:48:42 UTC
Update Date2013-02-09 00:10:06 UTC
HMDB IDHMDB01206
Secondary Accession NumbersNone
Metabolite Identification
Common NameAcetyl-CoA
DescriptionThe main function of coenzyme A is to carry acyl groups (such as the acetyl group) or thioesters. Acetyl-CoA is an important molecule itself. It is the precursor to HMG CoA, which is a vital component in cholesterol and ketone synthesis. (wikipedia). acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Structure
Thumb
Synonyms
  1. Ac-CoA
  2. Ac-Coenzyme A
  3. Ac-S-CoA
  4. Ac-S-Coenzyme A
  5. Acetyl coenzyme-A
  6. Acetyl-CoA
  7. Acetyl-Coenzyme A
  8. Acetyl-S-CoA
  9. Acetyl-S-Coenzyme A
  10. Acetylcoenzyme-A
  11. S-Acetate CoA
  12. S-Acetate Coenzyme A
  13. S-Acetyl coenzyme A
Chemical FormulaC23H38N7O17P3S
Average Molecular Weight809.571
Monoisotopic Molecular Weight809.125773051
IUPAC Name{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid
Traditional IUPAC Name[(2R,3S,4R,5R)-2-[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy(hydroxy)phosphoryl]oxy(hydroxy)phosphoryl}oxy)methyl]-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-3-yl]oxyphosphonic acid
CAS Registry Number72-89-9
SMILES
CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
InChI Identifier
InChI=1S/C23H38N7O17P3S/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38)/t13-,16-,17-,18+,22-/m1/s1
InChI KeyZSLZBFCDCINBPY-ZSJPKINUSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassLipids
ClassFatty Acid Esters
Sub ClassAcyl CoAs
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
  • acyl-CoA(ChEBI)
Substituents
  • 1 Phosphoribosyl Imidazole
  • Aminopyrimidine
  • Carboxamide Group
  • Carboxylic Thioester
  • Coenzyme A
  • Glycosyl Compound
  • Imidazole
  • Imidazopyrimidine
  • Monosaccharide Phosphate
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Organic Pyrophosphate
  • Oxolane
  • Pentose Monosaccharide
  • Phosphoric Acid Ester
  • Purine
  • Purine Ribonucleoside 3',5' Bisphosphate
  • Pyrimidine
  • Saccharide
  • Secondary Alcohol
  • Secondary Carboxylic Acid Amide
  • Thiocarboxylic Acid Ester
Direct ParentAcyl CoAs
Ontology
StatusExpected and Not Quantified
Origin
  • Endogenous
  • Food
Biofunction
  • Cell signaling
  • Component of Alanine and aspartate metabolism
  • Component of Aminosugars metabolism
  • Component of Arginine and proline metabolism
  • Component of Bile acid biosynthesis
  • Component of Butanoate metabolism
  • Component of Fatty acid metabolism
  • Component of Glutamate metabolism
  • Component of Glycerophospholipid metabolism
  • Component of Glycine, serine and threonine metabolism
  • Component of Glyoxylate and dicarboxylate metabolism
  • Component of Propanoate metabolism
  • Component of Pyruvate metabolism
  • Component of Tetracycline biosynthesis
  • Component of Tryptophan metabolism
  • Component of beta-Alanine metabolism
  • Fuel and energy storage
  • Fuel or energy source
  • Membrane integrity/stability
Application
  • Nutrients
  • Stabilizers
  • Surfactants and Emulsifiers
Cellular locations
  • Cytoplasm
  • Extracellular
  • Membrane
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Golgi apparatus
  • Peroxisome
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
water solubility4.3 g/LALOGPS
logP-0.58ALOGPS
logP-7ChemAxon
logS-2.3ALOGPS
pKa (strongest acidic)0.83ChemAxon
pKa (strongest basic)4.95ChemAxon
physiological charge-4ChemAxon
hydrogen acceptor count17ChemAxon
hydrogen donor count9ChemAxon
polar surface area363.63ChemAxon
rotatable bond count20ChemAxon
refractivity172.21ChemAxon
polarizability71.4ChemAxon
Spectra
SpectraNot Available
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Membrane
  • Mitochondria
  • Nucleus
  • Endoplasmic reticulum
  • Golgi apparatus
  • Peroxisome
Biofluid LocationsNot Available
Tissue Location
  • Adipose Tissue
  • Brain
  • Muscle
  • Platelet
  • Prostate
  • Skeletal Muscle
  • Spleen
Pathways
NameSMPDB LinkKEGG Link
Amino Sugar MetabolismSMP00045map00520
Beta Oxidation of Very Long Chain Fatty AcidsSMP00052map01040
Beta-Alanine MetabolismSMP00007map00410
Butyrate MetabolismSMP00073map00650
Citric Acid CycleSMP00057map00020
Ethanol DegradationSMP00449Not Available
Fatty Acid BiosynthesisSMP00456Not Available
Fatty acid MetabolismSMP00051map00071
Glycine and Serine MetabolismSMP00004map00260
Ketone Body MetabolismSMP00071map00072
Lysine DegradationSMP00037map00310
Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty AcidsSMP00482Not Available
Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty AcidsSMP00481Not Available
Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty AcidsSMP00480Not Available
Oxidation of Branched Chain Fatty AcidsSMP00030Not Available
Phytanic Acid Peroxisomal OxidationSMP00450Not Available
Propanoate MetabolismSMP00016map00640
Pyruvate MetabolismSMP00060map00620
Steroid BiosynthesisSMP00023map00100
Transfer of Acetyl Groups into MitochondriaSMP00466Not Available
Valine, Leucine and Isoleucine DegradationSMP00032map00280
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB022491
KNApSAcK IDNot Available
Chemspider ID392413
KEGG Compound IDC00024
BioCyc IDACETYL-COA
BiGG ID33558
Wikipedia LinkAcetyl-CoA
NuGOwiki LinkHMDB01206
Metagene LinkHMDB01206
METLIN ID6082
PubChem Compound444493
PDB IDACO
ChEBI ID15351
References
Synthesis ReferenceTucek, S. The synthesis of acetyl coenzyme A and acetylcholine from citrate and acetate in the nerve endings of mammalian brain. Biochimica et Biophysica Acta, General Subjects (1966), 117(1), 278-80.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Blank ML, Smith ZL, Fitzgerald V, Snyder F: The CoA-independent transacylase in PAF biosynthesis: tissue distribution and molecular species selectivity. Biochim Biophys Acta. 1995 Feb 9;1254(3):295-301. Pubmed: 7857969
  2. Wysocki SJ, Wilkinson SP, Hahnel R, Wong CY, Panegyres PK: 3-Hydroxy-3-methylglutaric aciduria, combined with 3-methylglutaconic aciduria. Clin Chim Acta. 1976 Aug 2;70(3):399-406. Pubmed: 947633
  3. Al-Buheissi SZ, Patel HR, Meinl W, Hewer A, Bryan RL, Glatt H, Miller RA, Phillips DH: N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation. Pharmacogenet Genomics. 2006 Jun;16(6):391-9. Pubmed: 16708048
  4. Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A: The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism. 2004 Jan;53(1):66-72. Pubmed: 14681844
  5. Griffin MJ, Sul HS: Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c. IUBMB Life. 2004 Oct;56(10):595-600. Pubmed: 15814457
  6. Putman CT, Spriet LL, Hultman E, Dyck DJ, Heigenhauser GJ: Skeletal muscle pyruvate dehydrogenase activity during acetate infusion in humans. Am J Physiol. 1995 May;268(5 Pt 1):E1007-17. Pubmed: 7762627
  7. Szutowicz A, Tomaszewicz M, Jankowska A, Madziar B, Bielarczyk H: [Mechanisms of selective vulnerability of cholinergic neurons to neurotoxic stimuli] Postepy Hig Med Dosw. 1999;53(2):263-75. Pubmed: 10355292
  8. Ingebretsen OC, Bakken AM, Farstad M: The content of coenzyme A, acetyl-CoA and long-chain acyl-CoA in human blood platelets. Clin Chim Acta. 1982 Dec 23;126(3):307-13. Pubmed: 7151284
  9. Michno A, Raszeja-Specht A, Jankowska-Kulawy A, Pawelczyk T, Szutowicz A: Effect of L-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons. Clin Chem. 2005 Sep;51(9):1673-82. Epub 2005 Jul 14. Pubmed: 16020499
  10. Constantin-Teodosiu D, Peirce NS, Fox J, Greenhaff PL: Muscle pyruvate availability can limit the flux, but not activation, of the pyruvate dehydrogenase complex during submaximal exercise in humans. J Physiol. 2004 Dec 1;561(Pt 2):647-55. Epub 2004 Oct 7. Pubmed: 15579544
  11. Crystal HA, Davies P: Cortical substance P-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type. J Neurochem. 1982 Jun;38(6):1781-4. Pubmed: 6176686
  12. Evans MK, Savasi I, Heigenhauser GJ, Spriet LL: Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1144-50. Pubmed: 11701427
  13. Peters SJ: Regulation of PDH activity and isoform expression: diet and exercise. Biochem Soc Trans. 2003 Dec;31(Pt 6):1274-80. Pubmed: 14641042
  14. Roe CR, Sweetman L, Roe DS, David F, Brunengraber H: Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride. J Clin Invest. 2002 Jul;110(2):259-69. Pubmed: 12122118
  15. Skibowska A, Raszeja-Specht A, Szutowicz A: Platelet function and acetyl-coenzyme A metabolism in type 1 diabetes mellitus. Clin Chem Lab Med. 2003 Sep;41(9):1136-43. Pubmed: 14598862
  16. Girard J: [Contribution of free fatty acids to impairment of insulin secretion and action. mechanism of beta-cell lipotoxicity] Med Sci (Paris). 2005 Dec;21 Spec No:19-25. Pubmed: 16598900
  17. Szutowicz A, Jankowska A, Tomaszewicz M: [Disturbances of glucose metabolism in epilepsy and other neurodegenerative diseases] Neurol Neurochir Pol. 2000;34 Suppl 8:59-66. Pubmed: 11780590
  18. Spriet LL, MacLean DA, Dyck DJ, Hultman E, Cederblad G, Graham TE: Caffeine ingestion and muscle metabolism during prolonged exercise in humans. Am J Physiol. 1992 Jun;262(6 Pt 1):E891-8. Pubmed: 1616022
  19. Constantin-Teodosiu D, Carlin JI, Cederblad G, Harris RC, Hultman E: Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise. Acta Physiol Scand. 1991 Dec;143(4):367-72. Pubmed: 1815472
  20. Boden G, Jadali F, White J, Liang Y, Mozzoli M, Chen X, Coleman E, Smith C: Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest. 1991 Sep;88(3):960-6. Pubmed: 1885781

Only showing the first 50 proteins. There are 179 proteins in total.

Enzymes

Gene Name:
HMGCL
Uniprot ID:
P35914
Reactions
3-Hydroxy-3-methylglutaryl-CoA unknown Acetyl-CoA + Acetoacetic aciddetails
Gene Name:
ACLY
Uniprot ID:
P53396
Reactions
ADP + Phosphoric acid + Acetyl-CoA + Oxalacetic acid unknown Adenosine triphosphate + Citric acid + Coenzyme Adetails
Adenosine triphosphate + Citric acid + Coenzyme A unknown ADP + Phosphoric acid + Acetyl-CoA + Oxalacetic aciddetails
Gene Name:
EP300
Uniprot ID:
Q09472
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
ACAT2
Uniprot ID:
Q9BWD1
Reactions
Acetyl-CoA unknown Coenzyme A + Acetoacetyl-CoAdetails
Acetyl-CoA + Butyryl-CoA unknown Coenzyme A + 3-Oxohexanoyl-CoAdetails
Gene Name:
CREBBP
Uniprot ID:
Q92793
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
SAT2
Uniprot ID:
Q96F10
Reactions
Acetyl-CoA + an alkane-alpha,omega-diamine unknown Coenzyme A + an N-acetyldiaminedetails
Acetyl-CoA + Putrescine unknown Coenzyme A + N-Acetylputrescinedetails
Gene Name:
MLYCD
Uniprot ID:
O95822
Reactions
Malonyl-CoA unknown Acetyl-CoA + CO(2)details
Malonyl-CoA unknown Acetyl-CoA + Carbon dioxidedetails
Gene Name:
ACACB
Uniprot ID:
O00763
Reactions
Adenosine triphosphate + Acetyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + Malonyl-CoAdetails
Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein unknown Malonyl-CoA + Holo-[carboxylase]details
Gene Name:
NAT1
Uniprot ID:
P18440
Reactions
Acetyl-CoA + an arylamine unknown Coenzyme A + an N-acetylarylaminedetails
2,4-Diamino-6-nitrotoluene + Acetyl-CoA unknown 4-Acetamido-2-amino-6-nitrotoluene + Coenzyme Adetails
Acetyl-CoA + Isoniazid unknown Coenzyme A + Acetylisoniaziddetails
Acetyl-CoA + Acetylhydrazine unknown Coenzyme A + N,N'-Diacetylhydrazinedetails
Gene Name:
NAT2
Uniprot ID:
P11245
Reactions
Acetyl-CoA + an arylamine unknown Coenzyme A + an N-acetylarylaminedetails
2,4-Diamino-6-nitrotoluene + Acetyl-CoA unknown 4-Acetamido-2-amino-6-nitrotoluene + Coenzyme Adetails
Acetyl-CoA + Isoniazid unknown Coenzyme A + Acetylisoniaziddetails
Acetyl-CoA + Acetylhydrazine unknown Coenzyme A + N,N'-Diacetylhydrazinedetails
Gene Name:
GTF3C4
Uniprot ID:
Q9UKN8
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
ACOT12
Uniprot ID:
Q8WYK0
Reactions
Acetyl-CoA + Water unknown Coenzyme A + Acetic aciddetails
Gene Name:
CHAT
Uniprot ID:
P28329
Reactions
Acetyl-CoA + Choline unknown Coenzyme A + Acetylcholine details
Gene Name:
NCOA3
Uniprot ID:
Q9Y6Q9
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
KAT2B
Uniprot ID:
Q92831
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
CRAT
Uniprot ID:
P43155
Reactions
Acetyl-CoA + L-Carnitine unknown Coenzyme A + L-Acetylcarnitinedetails
Gene Name:
SAT1
Uniprot ID:
P21673
Reactions
Acetyl-CoA + an alkane-alpha,omega-diamine unknown Coenzyme A + an N-acetyldiaminedetails
Acetyl-CoA + Putrescine unknown Coenzyme A + N-Acetylputrescinedetails
Gene Name:
AANAT
Uniprot ID:
Q16613
Reactions
Acetyl-CoA + a 2-arylethylamine unknown Coenzyme A + an N-acetyl-2-arylethylaminedetails
Acetyl-CoA + Serotonin unknown Coenzyme A + N-Acetylserotonindetails
Gene Name:
ACAA2
Uniprot ID:
P42765
Reactions
Acyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-oxoacyl-CoAdetails
Acyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxoacyl-CoAdetails
Succinyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxoadipyl-CoAdetails
Propionyl-CoA + Acetyl-CoA unknown Coenzyme A + 2-Methylacetoacetyl-CoAdetails
Acetyl-CoA + Butyryl-CoA unknown Coenzyme A + 3-Oxohexanoyl-CoAdetails
Octanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxodecanoyl-CoAdetails
Lauroyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxotetradecanoyl-CoAdetails
Tetradecanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxohexadecanoyl-CoAdetails
Decanoyl-CoA (n-C10:0CoA) + Acetyl-CoA unknown Coenzyme A + 3-Oxododecanoyl-CoAdetails
Hexanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxooctanoyl-CoAdetails
Gene Name:
CDY1
Uniprot ID:
Q9Y6F8
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
FASN
Uniprot ID:
P49327
Reactions
Acetyl-CoA + n malonyl-CoA + 2n NADPH unknown a long-chain fatty acid + (n+1) CoA + n CO(2) + 2n NADP(+)details
Acetyl-CoA + [acyl-carrier-protein] unknown Coenzyme A + acetyl-[acyl-carrier-protein]details
Acetyl-CoA + Acyl-carrier protein unknown Coenzyme A + Acetyl-[acyl-carrier protein]details
Gene Name:
KAT5
Uniprot ID:
Q92993
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
ACSS2
Uniprot ID:
Q9NR19
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Acetyl adenylate + Coenzyme A unknown Adenosine monophosphate + Acetyl-CoAdetails
Gene Name:
ACAT1
Uniprot ID:
P24752
Reactions
Acetyl-CoA unknown Coenzyme A + Acetoacetyl-CoAdetails
Acetyl-CoA + Butyryl-CoA unknown Coenzyme A + 3-Oxohexanoyl-CoAdetails
Gene Name:
NCOA1
Uniprot ID:
Q15788
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
HMGCS2
Uniprot ID:
P54868
Reactions
Acetyl-CoA + Water + Acetoacetyl-CoA unknown 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme Adetails
3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A unknown Acetyl-CoA + Water + Acetoacetyl-CoAdetails
Gene Name:
ACSS1
Uniprot ID:
Q9NUB1
Reactions
Adenosine triphosphate + Acetic acid + Coenzyme A unknown Adenosine monophosphate + Pyrophosphate + Acetyl-CoAdetails
Acetyl adenylate + Coenzyme A unknown Adenosine monophosphate + Acetyl-CoAdetails
Gene Name:
CS
Uniprot ID:
O75390
Reactions
Acetyl-CoA + Water + Oxalacetic acid unknown Citric acid + Coenzyme Adetails
Citric acid + Coenzyme A unknown Acetyl-CoA + Water + Oxalacetic aciddetails
Gene Name:
CDY2A
Uniprot ID:
Q9Y6F7
Reactions
Acetyl-CoA + [histone] unknown Coenzyme A + acetyl-[histone]details
Gene Name:
ACAA1
Uniprot ID:
P09110
Reactions
Acyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-oxoacyl-CoAdetails
Succinyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxoadipyl-CoAdetails
Propionyl-CoA + Acetyl-CoA unknown Coenzyme A + 2-Methylacetoacetyl-CoAdetails
Acetyl-CoA + Butyryl-CoA unknown Coenzyme A + 3-Oxohexanoyl-CoAdetails
Octanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxodecanoyl-CoAdetails
Lauroyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxotetradecanoyl-CoAdetails
Tetradecanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxohexadecanoyl-CoAdetails
Decanoyl-CoA (n-C10:0CoA) + Acetyl-CoA unknown Coenzyme A + 3-Oxododecanoyl-CoAdetails
Hexanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxooctanoyl-CoAdetails
OPC6-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxo-OPC8-CoAdetails
OPC4-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxo-OPC6-CoAdetails
(+)-7-Isojasmonic acid CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxo-OPC4-CoAdetails
Cervonyl coenzyme A + Acetyl-CoA unknown Coenzyme A + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexa-6,9,12,15,18,21-enoyl-CoAdetails
Docosa-4,7,10,13,16-pentaenoyl CoA + Acetyl-CoA unknown Coenzyme A + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapenta-6,9,12,15,18-enoyl-CoAdetails
Gene Name:
ACACA
Uniprot ID:
Q13085
Reactions
Adenosine triphosphate + Acetyl-CoA + Carbonic acid unknown ADP + Phosphoric acid + Malonyl-CoAdetails
Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein unknown Malonyl-CoA + Holo-[carboxylase]details
Gene Name:
HADHB
Uniprot ID:
P55084
Reactions
Acyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-oxoacyl-CoAdetails
Acyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxoacyl-CoAdetails
Succinyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxoadipyl-CoAdetails
Propionyl-CoA + Acetyl-CoA unknown Coenzyme A + 2-Methylacetoacetyl-CoAdetails
Acetyl-CoA + Butyryl-CoA unknown Coenzyme A + 3-Oxohexanoyl-CoAdetails
Octanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxodecanoyl-CoAdetails
Lauroyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxotetradecanoyl-CoAdetails
Tetradecanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxohexadecanoyl-CoAdetails
Decanoyl-CoA (n-C10:0CoA) + Acetyl-CoA unknown Coenzyme A + 3-Oxododecanoyl-CoAdetails
Hexanoyl-CoA + Acetyl-CoA unknown Coenzyme A + 3-Oxooctanoyl-CoAdetails
Gene Name:
GCAT
Uniprot ID:
O75600
Reactions
Acetyl-CoA + Glycine unknown Coenzyme A + L-2-Amino-3-oxobutanoic aciddetails
Acetyl-CoA + Glycine unknown Coenzyme A + L-2-Amino-3-oxobutanoic aciddetails
Gene Name:
ALDH6A1
Uniprot ID:
Q02252
Reactions
Malonic semialdehyde + Coenzyme A + NAD(P)(+) unknown Acetyl-CoA + CO(2) + NAD(P)Hdetails
Malonic semialdehyde + Coenzyme A + NAD unknown Acetyl-CoA + Carbon dioxide + NADH + Hydrogen Iondetails
Malonic semialdehyde + Coenzyme A + NADP unknown Acetyl-CoA + Carbon dioxide + NADPH + Hydrogen Iondetails
Gene Name:
GNPNAT1
Uniprot ID:
Q96EK6
Reactions
Acetyl-CoA + Glucosamine 6-phosphate unknown Coenzyme A + N-Acetyl-D-Glucosamine 6-Phosphatedetails
Gene Name:
HMGCS1
Uniprot ID:
Q01581
Reactions
Acetyl-CoA + Water + Acetoacetyl-CoA unknown 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme Adetails
3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A unknown Acetyl-CoA + Water + Acetoacetyl-CoAdetails
Gene Name:
DLAT
Uniprot ID:
P10515
Reactions
Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine unknown Coenzyme A + enzyme N(6)-(S-acetyldihydrolipoyl)lysinedetails
Acetyl-CoA + Enzyme N6-(dihydrolipoyl)lysine unknown Coenzyme A + [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysinedetails
Gene Name:
ACOX1
Uniprot ID:
Q15067
Gene Name:
ACOX2
Uniprot ID:
Q99424
Gene Name:
ACOX3
Uniprot ID:
O15254

Transporters

Only showing the first 50 proteins. There are 179 proteins in total.