Hmdb loader

HMDBP01553 (Cytochrome P450 2B6) Metabolite Associations

Displaying metabolite protein links 76 - 100 of 130 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB00139217-HydroxyticlopidineThumbC14H14ClNOS279.785
279.048462472
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  2. Walsky RL, Astuccio AV, Obach RS: Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6. J Clin Pharmacol. 2006 Dec;46(12):1426-38. [PubMed:17101742 ]
HMDB001391112-HydroxynevirapineThumbC15H14N4O2282.2973
282.111675712
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
HMDB00138974-ene-Valproic acidThumbC8H14O2142.1956
142.099379692
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
HMDB00138953',4'-DihydrodiolThumbC15H14N2O4286.2827
286.095356946		Not Available
HMDB0013866N-Desmethyltamoxifen31750-48-8ThumbC25H27NO357.488
357.209264491
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
  3. Crewe HK, Notley LM, Wunsch RM, Lennard MS, Gillam EM: Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen. Drug Metab Dispos. 2002 Aug;30(8):869-74. [PubMed:12124303 ]
  4. Desta Z, Ward BA, Soukhova NV, Flockhart DA: Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75. Epub 2004 May 24. [PubMed:15159443 ]
HMDB00138583-Dechloroethylifosfamide36761-83-8ThumbC5H12ClN2O2P198.588
198.032491857
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
  2. Lokiec F: Ifosfamide: pharmacokinetic properties for central nervous system metastasis prevention. Ann Oncol. 2006 May;17 Suppl 4:iv33-6. [PubMed:16702183 ]
  3. Chen CS, Jounaidi Y, Waxman DJ: Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450. Drug Metab Dispos. 2005 Sep;33(9):1261-7. Epub 2005 May 26. [PubMed:15919850 ]
  4. Roy P, Yu LJ, Crespi CL, Waxman DJ: Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos. 1999 Jun;27(6):655-66. [PubMed:10348794 ]
HMDB00138564-Hydroxycyclophosphamide40277-05-2ThumbC7H15Cl2N2O3P277.085
276.019734282
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
  3. Preiss R, Schmidt R, Baumann F, Hanschmann H, Hauss J, Geissler F, Pahlig H, Ratzewiss B: Measurement of 4-hydroxylation of ifosfamide in human liver microsomes using the estimation of free and protein-bound acrolein and codetermination of keto- and carboxyifosfamide. J Cancer Res Clin Oncol. 2002 Jul;128(7):385-92. Epub 2002 Jun 11. [PubMed:12136253 ]
HMDB00138403-Hydroxymethylantipyrine18125-49-0ThumbC11H12N2O2204.2252
204.089877638
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB001113619(S)-HETE79551-85-2ThumbC20H32O3320.4663
320.23514489		Not Available
HMDB000676919-Hydroxytestosterone2126-37-6ThumbC19H28O3304.4238
304.203844762		Not Available
HMDB000676819-Oxoandrost-4-ene-3,17-dioneThumbC19H24O3300.3921
300.172544634		Not Available
HMDB000505015H-11,12-EETA877878-78-9ThumbC20H32O4336.4657
336.230059512		Not Available
HMDB0005038Citalopram59729-33-8ThumbC20H21FN2O324.3919
324.163791509		Not Available
HMDB0005011Clopidogrel113665-84-2ThumbC16H16ClNO2S321.822
321.059027158		Not Available
HMDB0005010Sertraline79617-96-2ThumbC17H17Cl2N306.23
305.073804963		Not Available
HMDB0004995Codeine76-57-3ThumbC18H21NO3299.3642
299.152143543		Not Available
HMDB000470212,13-EpOMEThumbC18H32O3296.4449
296.23514489		Not Available
HMDB00047019,10-Epoxyoctadecenoic acidThumbC18H32O3296.4449
296.23514489		Not Available
HMDB000469411,14,15-THETAThumbC20H34O5354.481
354.240624198		Not Available
HMDB000469311H-14,15-EETA219535-29-2ThumbC20H32O4336.4657
336.230059512		Not Available
HMDB000468411,12,15-THETAThumbC20H34O5354.481
354.240624198		Not Available
HMDB000468016(R)-HETEThumbC20H32O3320.4663
320.23514489		Not Available
HMDB000467311,12-Epoxyeicosatrienoic acid123931-40-8ThumbC20H32O3320.473
320.23514489		Not Available
HMDB000426414,15-Epoxy-5,8,11-eicosatrienoic acid81276-03-1ThumbC20H32O3320.4663
320.23514489		Not Available
HMDB000424415(S)-HPETE70981-96-3ThumbC20H32O4336.4657
336.230059512		Not Available
Displaying metabolite protein links 76 - 100 of 130 in total