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Record Information
Version3.6
Creation Date2012-09-06 15:16:52 UTC
Update Date2016-02-11 01:33:16 UTC
HMDB IDHMDB15532
Secondary Accession NumbersNone
Metabolite Identification
Common NameZinc
DescriptionA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is known by the symbol Zn.
Structure
Thumb
Synonyms
ValueSource
30ZnChEBI
CincChEBI
ZincumChEBI
ZinkChEBI
ZnChEBI
ZN(II)ChEBI
ZN2+ChEBI
Chemical FormulaZn
Average Molecular Weight65.409
Monoisotopic Molecular Weight63.929146578
IUPAC Namezinc
Traditional Namezinc
CAS Registry Number7440-66-6
SMILES
[Zn]
InChI Identifier
InChI=1S/Zn
InChI KeyInChIKey=HCHKCACWOHOZIP-UHFFFAOYSA-N
Chemical Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous transition metal compounds
Sub ClassNot Available
Direct ParentHomogeneous transition metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous transition metal
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Ontology
StatusExpected but not Quantified
Origin
  • Drug
Biofunction
  • Trace Elements
Application
  • Pharmaceutical
Cellular locationsNot Available
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point419.5 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP0.16ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Biological Properties
Cellular LocationsNot Available
Biofluid Locations
  • Blood
  • Urine
Tissue LocationNot Available
Pathways
NameSMPDB LinkKEGG Link
5-oxoprolinase deficiencySMP00500Not Available
5-OxoprolinuriaSMP00143Not Available
Acute Intermittent PorphyriaSMP00344Not Available
AlkaptonuriaSMP00169Not Available
Beta Ureidopropionase DeficiencySMP00172Not Available
Celecoxib Metabolism PathwaySMP00644Not Available
Celecoxib PathwaySMP00096Not Available
Congenital Erythropoietic Porphyria (CEP) or Gunther DiseaseSMP00345Not Available
Cystathionine Beta-Synthase DeficiencySMP00177Not Available
Dihydropyrimidinase DeficiencySMP00178Not Available
Disulfiram PathwaySMP00429Not Available
Dopa-responsive dystoniaSMP00486Not Available
Dopamine beta-hydroxylase deficiencySMP00498Not Available
Fabry diseaseSMP00525Not Available
Fc Epsilon Receptor I Signaling in Mast CellsSMP00358Not Available
Felbamate Metabolism PathwaySMP00633Not Available
Gamma-glutamyl-transpeptidase deficiencySMP00501Not Available
Gamma-Glutamyltransferase DeficiencySMP00183Not Available
Gaucher DiseaseSMP00349Not Available
Gemcitabine Metabolism PathwaySMP00603Not Available
Gemcitabine PathwaySMP00446Not Available
Globoid Cell LeukodystrophySMP00348Not Available
Glutathione MetabolismSMP00015map00480
Glutathione Synthetase DeficiencySMP00337Not Available
Glycine N-methyltransferase DeficiencySMP00222Not Available
HawkinsinuriaSMP00190Not Available
Hereditary Coproporphyria (HCP)SMP00342Not Available
Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation typeSMP00570Not Available
HypermethioninemiaSMP00341Not Available
Hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiencySMP00487Not Available
Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency (ptps)SMP00488Not Available
Hyperphenylalaninemia due to dhpr-deficiencySMP00489Not Available
HypophosphatasiaSMP00503Not Available
Insulin SignallingSMP00391Not Available
Intracellular Signalling Through Adenosine Receptor A2a and AdenosineSMP00320Not Available
Intracellular Signalling Through Adenosine Receptor A2b and AdenosineSMP00321Not Available
Krabbe diseaseSMP00526Not Available
Metachromatic Leukodystrophy (MLD)SMP00347Not Available
Methionine Adenosyltransferase DeficiencySMP00221Not Available
Methionine MetabolismSMP00033map00270
Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)SMP00340Not Available
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)SMP00202Not Available
Monoamine oxidase-a deficiency (MAO-A)SMP00533Not Available
Porphyria Variegata (PV)SMP00346Not Available
Porphyrin MetabolismSMP00024map00860
Pterine BiosynthesisSMP00005map00790
Pyrimidine MetabolismSMP00046map00240
Retinol MetabolismSMP00074map00830
Riboflavin MetabolismSMP00070map00740
S-Adenosylhomocysteine (SAH) Hydrolase DeficiencySMP00214Not Available
Segawa syndromeSMP00490Not Available
Sepiapterin reductase deficiencySMP00491Not Available
Sphingolipid MetabolismSMP00034map00500
Tyrosine MetabolismSMP00006map00350
Tyrosinemia Type ISMP00218Not Available
Tyrosinemia, transient, of the newbornSMP00494Not Available
UMP Synthase Deiciency (Orotic Aciduria)SMP00219Not Available
Vitamin A DeficiencySMP00336Not Available
Vitamin B6 MetabolismSMP00017map00750
Normal Concentrations
BiofluidStatusValueAgeSexConditionReferenceDetails
BloodExpected but not QuantifiedNot ApplicableNot AvailableNot AvailableTaking drug identified by DrugBank entry DB01593
  • Not Applicable
details
UrineExpected but not QuantifiedNot ApplicableNot AvailableNot AvailableTaking drug identified by DrugBank entry DB01593
  • Not Applicable
details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB01593
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDNot Available
KNApSAcK IDNot Available
Chemspider ID22430
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkZinc
NuGOwiki LinkHMDB15532
Metagene LinkHMDB15532
METLIN IDNot Available
PubChem Compound23994
PDB IDNot Available
ChEBI ID27363
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available